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Chapter 5 - Drug-Induced Gastrointestinal Disease

Published online by Cambridge University Press:  06 June 2020

By
Aoife McCarthy  and
Kieran Sheahan
Edited by
Roger M. Feakins
Roger M. Feakins
Affiliation:
Royal Free London NHS Foundation Trust, London, UK
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Summary

The assessment of gastrointestinal (GI) specimens from immunosuppressed patients can be challenging, particularly because of the increased likelihood of multiple diseases and of rarer diseases. This chapter documents and presents the wide range of luminal GI pathologies that can develop in the three main groups of immunosuppressed patients, i.e. HIV/AIDS patients, individuals with primary immunodeficiencies, and patients receiving iatrogenic immunosuppression. These GI pathologies include infections, neoplasms, drug-related injuries, and diseases that are more specific to certain groups of immunosuppressed patients such as graft-versus-host disease in bone marrow transplant recipients.

Keywords

gastrointestinal tractimmunosuppressionHIVtransplantationimmunodeficiencyinfectionneoplasia
Type
Chapter
Information
Non-Neoplastic Pathology of the Gastrointestinal Tract
A Practical Guide to Biopsy Diagnosis
 , pp. 65 - 83
Publisher: Cambridge University Press
Print publication year: 2020

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