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Chapter 10 - Olfactory Dysfunction in Parkinson’s Disease and Related Disorders

Published online by Cambridge University Press:  05 March 2022

By
Richard L. Doty  and
Christopher H. Hawkes
Edited by
Néstor Gálvez-Jiménez ,
Amos D. Korczyn  and
Ramón Lugo-Sanchez
Néstor Gálvez-Jiménez
Affiliation:
Florida International University
Amos D. Korczyn
Affiliation:
Tel-Aviv University
Ramón Lugo-Sanchez
Affiliation:
Cleveland Clinic
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Summary

Smell dysfunction is among the earliest and most salient non-motor signs of Parkinson’s disease (PD), occurring in an estimated 90% of so-called sporadic cases years before the onset of the classic motor symptoms. Until olfaction is tested formally, the vast majority of PD patients are unaware of their loss, which is usually less than total. The smell problem is rarely identified by neurologists, reflecting, in part, their failure to enquire about smell function let alone testing the olfactory nerve formally. The Quality Standards Committee of the American Academy of Neurology has designated olfactory dysfunction as one of the key diagnostic criteria for PD [1] and the Movement Disorder Society has recommended olfactory testing in the diagnosis of PD [2] and in the identification of prodromal PD [3].

Type
Chapter
Information
Non-motor Parkinson's Disease , pp. 99 - 114
Publisher: Cambridge University Press
Print publication year: 2022

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