Book contents
- Neuromuscular Disease: A Case-Based Approach
- Neuromuscular Disease
- Copyright page
- Contents
- Contributors
- Foreword
- Preface to 2nd Edition
- Part I Evaluation and Treatment of Patients with a Neuromuscular Disorder
- Part II Neuromuscular Cases
- Disorders of the Anterior Horn Cell
- Peripheral Neuropathies
- Disorders of the Neuromuscular Junction
- Myopathies
- Case 36 Duchenne Muscular Dystrophy (DMD)
- Case 37 Becker Muscular Dystrophy (BMD)
- Case 38 Facioscapulohumeral Muscular Dystrophy (FSHD)
- Case 39 Myotonic Dystrophy Type 1 (DM1)
- Case 40 Myotonic Dystrophy Type 2 (DM2)
- Case 41 Limb Girdle Muscular Dystrophy (LGMD) R1, Calpain-Related
- Case 42 Limb Girdle Muscular Dystrophy (LGMD) R9, FKRP-Related
- Case 43 Bethlem Myopathy, a Collagen VI-Related Myopathy (LGMDD5); Ullrich Congenital Muscular Dystrophy
- Case 44 Oculopharyngeal Muscular Dystrophy (OPMD)
- Case 45 Emery–Dreifuss Muscular Dystrophy (EDMD)
- Case 46 Caveolinopathy, Rippling Muscle Disease
- Case 47 Distal Myopathies: Miyoshi Myopathy, Dysferlinopathy; Anoctaminopathy
- Case 48 Distal Myopathies: GNE Myopathy
- Case 49 Myofibrillar Myopathies: Desminopathy
- Case 50 Skeletal Muscle Channelopathies: Non-Dystrophic Myotonia; Myotonia Congenita (Becker)
- Case 51 Skeletal Muscle Channelopathies: Hypokalaemic Periodic Paralysis
- Case 52 Pompe Disease (Glycogen Storage Disease (GSD) Type II; α-Glucosidase Deficiency)
- Case 53 McArdle Disease (Glycogen Storage Disease (GSD) Type V); Myophosphorylase Deficiency, Rhabdomyolysis
- Case 54 Carnitine Palmitoyltransferase-II (CPT2) Deficiency
- Case 55 Mitochondrial Myopathies: Chronic Progressive External Ophthalmoplegia (CPEO)
- Case 56 Ryanodine Receptor 1 (RYR1)-Related Disorders
- Case 57 Congenital Myopathies: X-Linked Myotubular Myopathy
- Case 58 Congenital Myopathies: Nemaline Myopathy
- Case 59 Juvenile Dermatomyositis (JDM)
- Case 60 Dermatomyositis (DM)
- Case 61 Immune-Mediated Necrotizing Myopathy (IMNM)
- Case 62 Inclusion Body Myositis (IBM)
- Case 63 Endocrine Myopathy: Hypothyroid Myopathy; Hyperthyroid Myopathy
- Case 64 Drug-Induced Myopathies: Hydroxychloroquine Myopathy
- Case 65 A- or Paucisymptomatic HyperCKaemia
- Cases 66 Exertional Rhabdomyolysis
- Video legends
- Index
- References
Case 60 - Dermatomyositis (DM)
from Myopathies
Published online by Cambridge University Press: 29 November 2024
Book contents
- Neuromuscular Disease: A Case-Based Approach
- Neuromuscular Disease
- Copyright page
- Contents
- Contributors
- Foreword
- Preface to 2nd Edition
- Part I Evaluation and Treatment of Patients with a Neuromuscular Disorder
- Part II Neuromuscular Cases
- Disorders of the Anterior Horn Cell
- Peripheral Neuropathies
- Disorders of the Neuromuscular Junction
- Myopathies
- Case 36 Duchenne Muscular Dystrophy (DMD)
- Case 37 Becker Muscular Dystrophy (BMD)
- Case 38 Facioscapulohumeral Muscular Dystrophy (FSHD)
- Case 39 Myotonic Dystrophy Type 1 (DM1)
- Case 40 Myotonic Dystrophy Type 2 (DM2)
- Case 41 Limb Girdle Muscular Dystrophy (LGMD) R1, Calpain-Related
- Case 42 Limb Girdle Muscular Dystrophy (LGMD) R9, FKRP-Related
- Case 43 Bethlem Myopathy, a Collagen VI-Related Myopathy (LGMDD5); Ullrich Congenital Muscular Dystrophy
- Case 44 Oculopharyngeal Muscular Dystrophy (OPMD)
- Case 45 Emery–Dreifuss Muscular Dystrophy (EDMD)
- Case 46 Caveolinopathy, Rippling Muscle Disease
- Case 47 Distal Myopathies: Miyoshi Myopathy, Dysferlinopathy; Anoctaminopathy
- Case 48 Distal Myopathies: GNE Myopathy
- Case 49 Myofibrillar Myopathies: Desminopathy
- Case 50 Skeletal Muscle Channelopathies: Non-Dystrophic Myotonia; Myotonia Congenita (Becker)
- Case 51 Skeletal Muscle Channelopathies: Hypokalaemic Periodic Paralysis
- Case 52 Pompe Disease (Glycogen Storage Disease (GSD) Type II; α-Glucosidase Deficiency)
- Case 53 McArdle Disease (Glycogen Storage Disease (GSD) Type V); Myophosphorylase Deficiency, Rhabdomyolysis
- Case 54 Carnitine Palmitoyltransferase-II (CPT2) Deficiency
- Case 55 Mitochondrial Myopathies: Chronic Progressive External Ophthalmoplegia (CPEO)
- Case 56 Ryanodine Receptor 1 (RYR1)-Related Disorders
- Case 57 Congenital Myopathies: X-Linked Myotubular Myopathy
- Case 58 Congenital Myopathies: Nemaline Myopathy
- Case 59 Juvenile Dermatomyositis (JDM)
- Case 60 Dermatomyositis (DM)
- Case 61 Immune-Mediated Necrotizing Myopathy (IMNM)
- Case 62 Inclusion Body Myositis (IBM)
- Case 63 Endocrine Myopathy: Hypothyroid Myopathy; Hyperthyroid Myopathy
- Case 64 Drug-Induced Myopathies: Hydroxychloroquine Myopathy
- Case 65 A- or Paucisymptomatic HyperCKaemia
- Cases 66 Exertional Rhabdomyolysis
- Video legends
- Index
- References
Summary
A 38-year-old woman was referred to a dermatologist because of a rash in the face. She had been feeling low in energy for several months and in the past two months her arms and legs felt weak accompanied by myalgia. The rash had expanded to the extensor surfaces of hands and knees, upper chest, and neck. Serum CK was 4313 U/L (20 × ULN), and she was referred to the outpatient department for neuromuscular disorders with a presumed diagnosis of dermatomyositis.
Keywords
- Type
- Chapter
- Information
- Neuromuscular DiseaseA Case-Based Approach, pp. 247 - 251Publisher: Cambridge University PressPrint publication year: 2024
References
Suggested Reading
Bhai, SF, Dimachkie, MM, de Visser, M. Is it really myositis? Mimics and pitfalls. Best Pract Res Clin Rheumatol 2022;36(2):101764. doi: 10.1016/j.berh.2022.101764. Epub 2022 Jun 23. PMID: 35752578.CrossRefGoogle ScholarPubMed
Ezeofor, AJ, O’Connell, KA, Cobos, GA, et al. Distinctive cutaneous features of dermatomyositis in Black adults: a case series. JAAD Case Rep 2023;37:106–109. doi: 10.1016/j.jdcr.2023.05.019. PMID: 37396484; PMCID: PMC10314225.CrossRefGoogle ScholarPubMed
Gandiga, PC, Ghetie, D, Anderson, E, Aggrawal, R. Intravenous immunoglobulin in idiopathic inflammatory myopathies: a practical guide for clinical use. Curr Rheumatol Rep 2023;25(8):152–168. doi: 10.1007/s11926-023-01105-w. Epub 2023 Jun 1. PMID: 37261663CrossRefGoogle ScholarPubMed
Goswami, RP, Haldar, SN, Chatterjee, M, et al. Efficacy and safety of intravenous and subcutaneous immunoglobulin therapy in idiopathic inflammatory myopathy: a systematic review and meta-analysis. Autoimmun Rev 2022;21(2):102997. doi: 10.1016/j.autrev.2021.102997. Epub 2021 Nov 17. PMID: 34800685.CrossRefGoogle ScholarPubMed
La Rocca, G, Ferro, F, Baldini, C, et al. Targeting intracellular pathways in idiopathic inflammatory myopathies: a narrative review. Front Med (Lausanne) 2023;10:1158768. doi: 10.3389/fmed.2023.1158768. PMID: 36993798; PMCID: PMC10040547.CrossRefGoogle ScholarPubMed
Lundberg, IE, de Visser, M, Werth, VP. Classification of myositis. Nat Rev Rheumatol 2018;14(5):269–278. doi: 10.1038/nrrheum.2018.41. Epub 2018 Apr 12. PMID: 29651121.CrossRefGoogle ScholarPubMed
Mammen, AL, Allenbach, Y, Stenzel, W, Benveniste, O ; ENMC 239th Workshop Study Group. 239th ENMC International Workshop: classification of dermatomyositis, Amsterdam, the Netherlands, 14-16 December 2018. Neuromuscul Disord 2020;30(1):70–92. doi: 10.1016/j.nmd.2019.10.005. Epub 2019 Oct 25. PMID: 31791867.CrossRefGoogle ScholarPubMed
Oldroyd, AGS, Callen, JP, Chinoy, H, et al.; International Myositis Assessment and Clinical Studies Group Cancer Screening Expert Group; Aggarwal, R. International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative. Nat Rev Rheumatol 2023;19(12):805–817. doi: 10.1038/s41584-023-01045-w. Epub ahead of print. PMID: 37945774.CrossRefGoogle Scholar
Tanboon, J, Nishino, I. Update on dermatomyositis. Curr Opin Neurol 2022;35(5):611–621. doi: 10.1097/WCO.0000000000001091. Epub 2022 Aug 4. PMID: 35942671.CrossRefGoogle ScholarPubMed