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Published online by Cambridge University Press:  21 November 2024

James Dolbow
Affiliation:
University Hospitals Cleveland Medical Center
Neel Fotedar
Affiliation:
University Hospitals Cleveland Medical Center
Joshua Edmondson
Affiliation:
University Hospital Cleveland Medical Centter
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Summary

Autoimmune encephalitis (AI) is a relatively newly defined group of noninfectious, immune-mediated inflammatory conditions of the brain parenchyma. First described in the 1960s, AI was originally found to be a paraneoplastic limbic encephalitis due to small cell lung cancer. A decade later research proved that this condition is caused by antibodies directed against either intracellular onconeuronal antigens, for example, anti-Hu or against the neuronal surface antigens, for example, anti-N-methyl-D-aspartate receptor (NMDAR). Most of the classic paraneoplastic autoimmune encephalitides belong to the former category.

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The Neurology Riddle Book
150 Common and Rare Neurological Diseases in Riddle Form
, pp. 137 - 140
Publisher: Cambridge University Press
Print publication year: 2024

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  • 44
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.046
Available formats
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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • 44
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.046
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • 44
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.046
Available formats
×