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9 - Striatal implementation of action sequences and more: grooming chains, inhibitory gating, and the relative reward effect

Published online by Cambridge University Press:  04 August 2010

By
Howard Casey Cromwell
Edited by
Allan V. Kalueff ,
Justin L. La Porte  and
Carisa L. Bergner
Allan V. Kalueff
Affiliation:
National Institute of Mental Health, Washington DC
Justin L. La Porte
Affiliation:
National Institute of Mental Health, Washington DC
Carisa L. Bergner
Affiliation:
National Institute of Mental Health, Washington DC
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Summary

Summary

The striatum is a subcortical structure thought to be important for higher motor functions and reward processing. It is part of a larger system called the basal ganglia (BG) and composed of multiple subregions thought to be functionally heterogeneous. This review provides information and evidence for the role of the striatum in implementing the fixed action pattern of the grooming chain in the rat. The support for the involvement of the dorsolateral striatal subregion involved in the production of this movement sequence is described, and the general functional significance of implementation by striatal circuitry is discussed. Implementation is meant to refer to the ability of local processing within striatal circuits to enable motor action plans to be completed without distraction from competing sensory or motor demands. The idea that the striatum is involved in more than motor functions is developed and evidence for detailed processing of reward outcomes is presented. We introduce the possibility that the general nature of striatal function of “implementing” chains of information crosses different functional boundaries between movement and reward information. For movement plans, the implementation includes enabling motor sequences for appropriate output and for reward plans, the implementation includes enabling reward incentive hierarchies for appropriate outcome choices. These types of functions could rely upon cross-talk among striatal subregions and reveal a possible shared integrative function for the different “loops” of the BG circuitry.

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Neurobiology of Grooming Behavior , pp. 156 - 183
Publisher: Cambridge University Press
Print publication year: 2010

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