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4 - Postnatal growth in preterm infants

Published online by Cambridge University Press:  10 December 2009

Patti J. Thureen
Affiliation:
University of Colorado at Denver and Health Sciences Center
Richard J. Cooke
Affiliation:
Department of Pediatrics, University of Tennessee Newborn Center, Memphis, Tennessee
William W. Hay
Affiliation:
University of Colorado at Denver and Health Sciences Center
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Summary

Introduction

The fundamental principle in providing nutritional support is to ensure that intake meets requirements thereby ensuring that inadequate intake is not rate-limiting on outcome. However, translating principles into practice is not simple in the preterm, particularly the very-low birth weight infant (VLBWI).

It takes time to establish adequate dietary intakes in the immature infant, and infants become malnourished during initial hospital stay. Yet, recommended dietary intakes (RDI) are based on needs for maintenance and normal growth, but no allowance is made for ‘catch-up’ growth, a critical consideration in the preterm infant. Accurate and reproducible measures of outcome also are not fully agreed upon.

Any discussion on postnatal growth in preterm infants, therefore, tends to raise more questions than answers. It is recommended that once birth weight has been regained, growth parallels that of the fetus at the same gestational age. But what is acceptable early weight loss? Is fetal growth an appropriate reference for postnatal growth? How should growth be assessed? In this chapter, these issues will be discussed, as will a few studies examining postnatal growth in this high-risk population.

Early weight loss

The importance of early weight loss cannot be underestimated. This is illustrated in Figure 4.1. A 27-week gestation 1007 g infant who regains birth weight by the end of the second week and then grows at a rate which parallels that in utero will weigh ∼541 g less than the intrauterine fetus at 37-week gestation.

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Publisher: Cambridge University Press
Print publication year: 2006

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References

Carlson, S. J., Ziegler, E. E.Nutrient intakes and growth of very low birth weight infants. J. Perinatol. 1998a;18:252–8.Google Scholar
Embleton, N. E., Pang, N., Cooke, R. J.Postnatal malnutrition and growth retardation: an inevitable consequence of current recommendations in preterm infants?Pediatrics 2001;107:270–3.CrossRefGoogle ScholarPubMed
American Academy of Pediatric Committee on Nutrition. Nutritional needs of preterm infants. In Kleinman, R. E., ed. Pediatric Nutrition Handbook. Elk Groove Village, IL: American Academy of Pediatrics; 1998:55–88.Google Scholar
Klein, C. J.Nutrient requirements for preterm infant formulas. J. Nutr. 2002:132:1395S–577S.CrossRefGoogle ScholarPubMed
Kashyap, S., Heird, W. C. Protein requirements of low birth weight, very low birth weight, and small for gestational age infants. In Raiha, N., ed. Protein Metabolism during Infancy. New York, NY: Raven Press; 1994:133–51.Google Scholar
Brace, R. A. Fluid distribution in the fetus and neonate. In Poland, R. A., Fox, W. W., eds. Fetal and Neonatal Physiology. Philadelphia, PA: WB Saunders; 1998:1703–13.Google Scholar
Cooke, R. J., Ford, A., Werkman, S., Conner, C., Watson, D.Postnatal growth in infants born between 700 and 1500 g. J. Pediatr. Gastroenterol. Nutr. 1993;16:130–5.CrossRefGoogle Scholar
Bauer, K., Bovermann, G., Roithmaier, A.et al.Body composition, nutrition, and fluid balance during the first two weeks of life in preterm neonates weighing less than 1500 grams. J. Pediatr. 1991;118:615–20.CrossRefGoogle ScholarPubMed
Putet, G. Energy. In Tsang, R. C., Lucas, A., Uauy, R., Zlotkin, S., eds. Nutritional Needs of Preterm Infants: Scientific Basis and Practical Guidelines. Baltimore, MD: Williams & Wilkins; 1993:15–28.Google Scholar
Anderson, T. L., Muttart, C. R., Bieber, M. A., Nicholson, J. F., Heird, W. C.A controlled trial of glucose versus glucose and amino acids in premature infants. J. Pediatr. 1979;94:947–51.CrossRefGoogle ScholarPubMed
Cooke, R. J., Werkman, S., Watson, D.Urine output measurement in premature infants. Pediatrics 1989;83:116–18.Google ScholarPubMed
Ehrenkranz, R. A., Younes, N., Lemons, J. A., et al.Longitudinal growth of hospitalized very low birth weight infants. Pediatrics 1999;104:280–9.CrossRefGoogle ScholarPubMed
Wilson, D. C., Cairns, P., Halliday, H. L.et al.Randomised controlled trial of an aggressive nutritional regimen in sick very low birthweight infants. Arch. Dis. Child. Fetal Neonatal Ed. 1997;77:F4–11.CrossRefGoogle ScholarPubMed
Sparks, J. W.Human intrauterine growth and nutrient accretion. Semin Perinatol. 1984;8:74–93.Google ScholarPubMed
Sparks, J. W., Ross, J. C., Cetin, I. Intrauterine growth and nutrition. In Polin, R. A., Fox, W. W., eds. Fetal and Neonatology Physiology. 2nd edn. Philadelphia, PA: WB Saunders Co; 1998:267–89.Google Scholar
Gallivan, S., Robson, S. C., Chang, T. C., Vaughan, J., Spencer, J. A.An investigation of fetal growth using serial ultrasound data. Ultrasound Obstet. Gynecol. 1993;3:109–14.CrossRefGoogle ScholarPubMed
Chang, T. C., Robson, S. C., Spencer, J. A., Gallivan, S.Ultrasonic fetal weight estimation: analysis of inter- and intra-observer variability. J. Clin. Ultrasound 1993;21:515–19.CrossRefGoogle ScholarPubMed
Robson, S. C., Gallivan, S., Walkinshaw, S. A., Vaughan, J., Rodeck, C. H.Ultrasonic estimation of fetal weight: use of targeted formulas in small for gestational age fetuses. Obstet. Gynecol. 1993;82:359–64.Google ScholarPubMed
Lubchenco, L. O.Intrauterine growth as estimated from liveborn birth-weight data at 24 to 42 weeks of gestation. Pediatrics 1963;32:793–800.Google ScholarPubMed
Usher, R., McLean, F.Intrauterine growth of live-born Caucasian infants at sea level: standards obtained from measurements in 7 dimensions of infants born between 25 and 44 weeks of gestation. J. Pediatr. 1969;74:901–10.CrossRefGoogle ScholarPubMed
Gruenwald, P.Growth of the human fetus. I. Normal growth and its variation. Am. J. Obstet. Gynecol. 1966;94:1112–19.CrossRefGoogle ScholarPubMed
Thompson, J. M., Clark, P. M., Robinson, E.et al.Risk factors for small-for-gestational-age babies: The Auckland Birthweight Collaborative Study. J. Paediatr. Child Health 2001;37:369–75.CrossRefGoogle ScholarPubMed
Arbuckle, T. E., Wilkins, R., Sherman, G. J.Birth weight percentiles by gestational age in Canada. Obstet. Gynecol. 1993;81:39–48.Google Scholar
Battaglia, F. C., Frazier, T. M., Hellegers, A. E.Birth weight, gestational age, and pregnancy out-come, with special reference to high birth weight-low gestational age infant. Pediatrics 1966;37:417–22.Google ScholarPubMed
Berg, A. T., Bracken, M. B.Measuring gestational age: an uncertain proposition. Br. J. Obstet. Gynaecol. 1992;99:280–2.CrossRefGoogle Scholar
Naeye, R. L., Dixon, J. B.Distortions in fetal growth standards. Pediatr. Res. 1978;12:987–91.CrossRefGoogle ScholarPubMed
Briend, A. Normal fetal growth regulation: nutritional aspects. In Gracey, M. G., Falkner, F., eds. Nutritional Needs and Assessment of Normal Growth. New York, NY: Raven Press; 1985:1–21.Google Scholar
Fedrick, J., Adelstein, P.Factors associated with low birth weight of infants delivered at term. Br. J. Obstet. Gynaecol. 1978;85:1–7.CrossRefGoogle ScholarPubMed
Larsen, T., Greisen, G., Petersen, S.Prediction of birth weight by ultrasound-estimated fetal weight: a comparison between single and repeated estimates. Eur. J. Obstet. Gynecol. Reprod. Biol. 1995;60:37–40.CrossRefGoogle ScholarPubMed
Larsen, T., Petersen, S., Greisen, G., Larsen, J. F.Normal fetal growth evaluated by longitudinal ultrasound examinations. Early Hum. Dev. 1990;24:37–45.CrossRefGoogle ScholarPubMed
Greisen, G.Estimation of fetal weight by ultrasound. Horm. Res. 1992;38:208–10.CrossRefGoogle ScholarPubMed
Thomson, A. M., Billewicz, W. Z., Hytten, F. E.The assessment of fetal growth. J. Obstet. Gynaecol. Br. Commonw. 1968;75:903–16.CrossRefGoogle ScholarPubMed
Babson, S. G., Behrman, R. E., Lessel, R.Fetal growth. Liveborn birth weights for gestational age of white middle class infants. Pediatrics 1970;45:937–44.Google ScholarPubMed
Brenner, W. E., Edelman, D. A., Hendricks, C. H.A standard of fetal growth for the United States of America. Am. J. Obstet. Gynecol. 1976;126:555–64.CrossRefGoogle ScholarPubMed
Alexander, G. R., Himes, J. H., Kaufman, R. B., Mor, J., Kogan, M.A United States national reference for fetal growth. Obstet. Gynecol. 1996;87:163–8.CrossRefGoogle ScholarPubMed
Babson, S. G., Bramhall, J. L.Diet and growth in the premature infant. The effect of different dietary intakes of ash-electrolyte and protein on weight gain and linear growth. J. Pediatr. 1969;74:890–900.CrossRefGoogle ScholarPubMed
Davies, D. P. Physical growth from fetus to early childhood. In Dobbing, J., ed. Scientific Foundation of Paediatrics. London: William Heinemann; 1981:303–30.Google Scholar
Lucas, A. Enteral nutrition. In Tsang, R., Lucas, A., Uauy, R., Zlotkin, S., eds. Nutritional Needs of the Preterm Infant: Scientific Basis and Practical Guidelines. Pawling, NY: Caduceus Medical Publishers, Inc. for Williams & Wilkins; 1993:209–23.Google Scholar
Fomon, S. Size and growth. In Fomon, S., ed. Nutrition of Normal Infants. 2nd edn. St Louis, MO: Mosby; 1993:36–84.Google Scholar
Hermanussen, M.Knemometry, a new tool for the investigation of growth. A review. Eur. J. Pediatr. 1988;147:350–5.CrossRefGoogle ScholarPubMed
Davies, H. A., Pickering, M., Wales, J. K.A portable knemometer: a technique for assessment of short-term growth. Ann. Hum. Biol. 1996;23:149–57.CrossRefGoogle ScholarPubMed
Gibson, A. T., Pearse, R. G., Wales, J. K.Knemometry and the assessment of growth in premature babies. Arch. Dis. Child. 1993;69:498–504.CrossRefGoogle ScholarPubMed
Wales, J. K., Milner, R. D.Knemometry in assessment of linear growth. Arch. Dis. Child. 1987;62:166–71.CrossRefGoogle ScholarPubMed
Griffin, I. J., Pang, N. M., Perring, J., Cooke, R. J.Knee-heel length measurement in healthy preterm infants. Arch. Dis. Child. Fetal Neonatal Edn 1999;81:F50–5.CrossRefGoogle ScholarPubMed
Katrine, K. F. Anthropometric assessment. In Groh-Wargo, S., Thompson, M., Cox, J., eds. Nutritional Care for High-Risk Newborns. 3rd edn. Chicago, IL: Precept Press; 2000:11–22.Google Scholar
Brunton, J. A., Bayley, H. S., Atkinson, S. A.Validation and application of dual-energy x-ray absorptiometry to measure bone mass and body composition in small infants. Am. J. Clin. Nutr. 1993;58:839–45.CrossRefGoogle ScholarPubMed
Roubenoff, R., Kehayias, J. J., Dawson-Hughes, B., Heymsfield, S. B.Use of dual-energy x-ray absorptiometry in body-composition studies: Not yet a ‘gold standard’. Am. J. Clin. Nutr. 1993;58:589–91.CrossRefGoogle Scholar
Tothill, P., Roubenoff, R., Kehayias, J. J., Dawson Hughes, B., Heymsfield, S. B.Limitations of dual-energy x-ray absorptiometry (1). Am. J. Clin. Nutr. 1995;61:398–400.CrossRefGoogle Scholar
Picaud, J. C., Rigo, J., Nyamugabo, K., Milet, J., Senterre, J.Evaluation of dual-energy X-ray absorptiometry for body-composition assessment in piglets and term human neonates. Am. J. Clin. Nutr. 1996;63:157–63.CrossRefGoogle ScholarPubMed
Brunton, J. A., Weiler, H. A., Atkinson, S. A.Improvement in the accuracy of dual energy x-ray absorptiometry for whole body and regional analysis of body composition: validation using piglets and methodologic considerations in infants. Pediatr. Res. 1997;41:590–6.CrossRefGoogle ScholarPubMed
Cooke, R. J., Rawlings, D. J., McCormick, K.et al.Body composition of preterm infants during infancy. Arch. Dis. Child. Fetal Neonatal Edn. 1999;80:F188–91.Google ScholarPubMed
Fomon, S., Haschke, F., Ziegler, E., Nelson, S.Body composition of reference children from birth to age 10 years. Am. J. Clin. Nutr. 1982;35:1169–75.CrossRefGoogle ScholarPubMed
Hannan, W. J., Cowen, S. J., Wrate, R. M., Barton, J.Improved prediction of bone mineral content and density. Arch. Dis. Child. 1995;72:147–9.CrossRefGoogle ScholarPubMed
Braillon, P. M., Salle, B. L., Brunet, J.et al.Dual energy x-ray absorptiometry measurement of bone mineral content in newborns: validation of the technique. Pediatr. Res. 1992;32:77–80.CrossRefGoogle ScholarPubMed
Pieltain, C., Curtis, M., Gerard, P., Rigo, J.Weight gain composition in preterm infants with dual energy X-ray absorptiometry. Pediatr. Res. 2001;49:120–4.CrossRefGoogle ScholarPubMed
Cooke, R. J., McCormick, K., Griffin, I. J.et al.Feeding preterm infants after hospital discharge: effect of diet on body composition. Pediatr Res. 1999;46:461–4.CrossRefGoogle ScholarPubMed
Ernst, J. A., Bull, M. J., Rickard, K. A., Brady, M. S., Lemons, J. A.Growth outcome and feeding practices of the very low birth weight infant (less than 1500 grams) within the first year of life. J. Pediatr. 1990;117:S156–6.CrossRefGoogle ScholarPubMed
Casey, P. H., Kraemer, H. C., Bernbaum, J.et al.Growth patterns of low birth weight preterm infants: a longitudinal analysis of a large, varied sample. J. Pediatr. 1990;117:298–307.CrossRefGoogle ScholarPubMed
Fitzhardinge, P. M., Inwood, S.Long-term growth in small-for-date children. Acta Paediatr. Scand. Suppl. 1989;349:27–34.CrossRefGoogle ScholarPubMed
Fenton, T. R., McMillan, D. D., Sauve, R. S.Nutrition and growth analysis of very low birth weight infants. Pediatrics 1990;86:378–83.Google ScholarPubMed
Kitchen, W. H., Doyle, L. W., Ford, G. W., Callanan, C.Very low birth weight and growth to age 8 years. I: Weight and height. Am. J. Dis. Child. 1992;146:40–5.CrossRefGoogle ScholarPubMed
Kitchen, W. H., Doyle, L. W., Ford, G. W.et al.Very low birth weight and growth to age 8 years. II: Head dimensions and intelligence. Am. J. Dis. Child. 1992;146:46–50.CrossRefGoogle ScholarPubMed
Ross, G., Lipper, E. G., Auld, P. A.Growth achievement of very low birth weight premature children at school age. J. Pediatr. 1990;117:307–9.CrossRefGoogle ScholarPubMed
McCormick, M. C., Shapiro, S., Starfield, B. H.Rehospitalization in the first year of life for high-risk survivors. Pediatrics 1980;66:991–9.Google ScholarPubMed
Hack, M., Caron, B., Rivers, A., Fanaroff, A. A.The very low birth weight infant: the broader spectrum of morbidity during infancy and early childhood. J. Dev. Behav. Pediatr. 1983;4:243–9.CrossRefGoogle ScholarPubMed
Navas, L., Wang, E., Carvalho, V., Robinson, J.Improved outcome of respiratory syncytial virus infection in a high-risk hospitalized population of Canadian children. Pediatric Investigators Collaborative Network on Infections in Canada. J. Pediatr. 1992;121:348–54.CrossRefGoogle Scholar
Thomas, M., Bedford-Russel, A., Sharland, M.Hospitalisation of RSV infection in ex-preterm infants – implications for RSV immune globulin. Arch. Dis. Child. 2000;83:122–7.CrossRefGoogle ScholarPubMed
Wang, E., Law, B., Stephens, D.Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalised with respiratory syncytial viral lower respiratory tract infection. J. Pediatr. 1995;126:212–19.CrossRefGoogle Scholar
Lucas, A., Bishop, N. J., King, F. J., Cole, T. J.Randomised trial of nutrition for preterm infants after discharge. Arch. Dis. Child. 1992;67:324–7.CrossRefGoogle ScholarPubMed
Bishop, N. J., King, F. J., Lucas, A.Increased bone mineral content of preterm infants fed with a nutrient enriched formula after discharge from hospital. Arch. Dis. Child. 1993;68:573–8.CrossRefGoogle ScholarPubMed
Chan, G. M., Borschel, M. W., Jacobs, J. R.Effects of human milk or formula feeding on the growth, behavior, and protein status of preterm infants discharged from the newborn intensive care unit. Am. J. Clin. Nutr. 1994;60:710–16.CrossRefGoogle ScholarPubMed
Cooke, R. J., Griffin, I. J., McCormick, K., et al.Feeding preterm infants after hospital discharge: Effect of dietary manipulation on nutrient intake and growth. Pediatr. Res. 1998;43:355–60.CrossRefGoogle Scholar
Carver, J. D., Wu, P. Y., Hall, R. T., et al.Growth of preterm infants fed nutrient-enriched or term formula after hospital discharge. Pediatrics 2001;107:683–9.CrossRefGoogle ScholarPubMed

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  • Postnatal growth in preterm infants
    • By Richard J. Cooke, Department of Pediatrics, University of Tennessee Newborn Center, Memphis, Tennessee
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.005
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  • Postnatal growth in preterm infants
    • By Richard J. Cooke, Department of Pediatrics, University of Tennessee Newborn Center, Memphis, Tennessee
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.005
Available formats
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To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Postnatal growth in preterm infants
    • By Richard J. Cooke, Department of Pediatrics, University of Tennessee Newborn Center, Memphis, Tennessee
  • Patti J. Thureen, University of Colorado at Denver and Health Sciences Center
  • Edited by William W. Hay, University of Colorado at Denver and Health Sciences Center
  • Book: Neonatal Nutrition and Metabolism
  • Online publication: 10 December 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544712.005
Available formats
×