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3 - Predictive Modeling for Biomarker Discovery

from Part I - Framework for Multivariate Biomarker Discovery

Published online by Cambridge University Press:  30 May 2024

Darius M. Dziuda
Affiliation:
Central Connecticut State University
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Summary

Chapter 3 provides an overview of all elements of the predictive modeling process, from the selection of training and test data sets, parallel multivariate feature selection experiments and deciding on an optimal multivariate biomarker, to building, tuning, validating, and testing predictive models implementing the optimal biomarker. Discussed are also such topics as bias-variance tradeoff, segmentation models, and committees of predictive models.

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Multivariate Biomarker Discovery
Data Science Methods for Efficient Analysis of High-Dimensional Biomedical Data
, pp. 25 - 43
Publisher: Cambridge University Press
Print publication year: 2024

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