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Chapter 35 - Sleep and Men’s Health

from Section 5 - Medical and Surgical Management of Issues of Male Health

Published online by Cambridge University Press:  06 December 2023

By
Vanessa Peña ,
Taylor P. Kohn  and
Larry I. Lipshultz
Edited by
Douglas T. Carrell ,
Alexander W. Pastuszak  and
James M. Hotaling
Douglas T. Carrell
Affiliation:
Utah Center for Reproductive Medicine
Alexander W. Pastuszak
Affiliation:
University of Utah
James M. Hotaling
Affiliation:
Utah Center for Reproductive Medicine
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Summary

More than one-third of American adults fail to achieve the 7–9 hours of sleep recommended by the American Academy of Sleep Medicine and the Sleep Research Society needed for optimal health and well-being. In addition to primary sleep disorders, such as sleep apnea, insomnia, and restless legs syndrome, many modern societal factors are also thought to contribute to chronic sleep deficiency, such as technology and work-related factors. Interruptions in the natural sleep–wake cycle can be associated with shift work and numerous chronic health conditions. A few studies have investigated the impact of nonstandard shift work on male reproductive health, and a compelling association between sleep and male urogenital health has been demonstrated. This chapter will review the literature on the effect of sleep and shift work on ED, LUTS, hypogonadism, male infertility, and how improved sleep quality can possibly improve common men’s health conditions.

Keywords

men’s healthsleeperectile dysfunctionlower urinary tract symptoms
Type
Chapter
Information
Men's Reproductive and Sexual Health Throughout the Lifespan
An Integrated Approach to Fertility, Sexual Function, and Vitality
 , pp. 279 - 288
Publisher: Cambridge University Press
Print publication year: 2023

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References

Krueger, JM, Frank, MG, Wisor, JP, Roy, S. Sleep function: toward elucidating an enigma. Sleep Med Rev. 2016;28:46–54. doi:10.1016/j.smrv.2015.08.005.Google Scholar
Centers for Disease Control and Prevention. Short sleep duration among US adults. www.cdc.gov/sleep/data_statistics.html. Updated 2017. Accessed June 26, 2020.Google Scholar
Watson, NF, Badr, MS, Belenky, G, et al. Joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: methodology and discussion. J Clin Sleep Med. 2015;11(8):931–952. doi:10.5664/jcsm.4950.Google Scholar
Luyster, FS, Strollo, PJ, Zee, PC, Walsh, JK. Sleep: a health imperative. Sleep. 2012;35(6):727–734. doi:10.5665/sleep.1846.Google Scholar
McMenamin, TM. A time to work: recent trends in shift work and flexible schedules. Mon Labor Rev. 2007;130(12):3–15. www.scopus.com/inward/record.uri?eid=2-s2.0-39749201717&partnerID=40&md5=394413e24b44176f8bcdb03b6e58a218. Accessed June 27, 2020.Google Scholar
Åkerstedt, T, Wright, KP. Sleep loss and fatigue in shift work and shift work disorder. Sleep Med Clin. 2009;4(2):257–271. doi: 10.1016/j.jsmc.2009.03.001.Google Scholar
Sateia, MJ. International classification of sleep disorders – third edition. Chest. 2014;146(5):1387–1394. doi:10.1378/chest.14-0970.Google Scholar
Drake, CL, Roehrs, T, Richardson, G, Walsh, JK, Roth, T. Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. Sleep. 2004;27(8):1453–1462. doi:10.1093/sleep/27.8.1453.Google Scholar
Vanttola, P, Puttonen, S, Karhula, K, Oksanen, T, Härmä, M. Prevalence of shift work disorder among hospital personnel: a cross-sectional study using objective working hour data. J Sleep Res. 2019;29(3):e12906. doi:10.1111/jsr.12906.Google Scholar
Fekedulegn, D, Burchfiel, CM, Hartley, TA, et al. Shiftwork and sickness absence among police officers: the BCOPS study. Chronobiol Int. 2013;30(7):930–941. doi:10.3109/07420528.2013.790043.Google Scholar
Nätti, J, Oinas, T, Härmä, M, Anttila, T, Kandolin, I. Combined effects of shiftwork and individual working time control on long-term sickness absence: a prospective study of Finnish employees. J Occup Environ Med. 2014;56(7):732–738. doi:10.1097/JOM.0000000000000176.Google Scholar
Lockley, SW, Barger, LK, Ayas, NT, Rothschild, JM, Czeisler, CA, Landrigan, CP. Effects of health care provider work hours and sleep deprivation on safety and performance. Jt Comm J Qual Patient Saf. 2007;33(Suppl. 11):7–18. doi:10.1016/S1553-7250(07)33109-7.Google Scholar
Keller, SM. Effects of extended work shifts and shift work on patient safety, productivity, and employee health. AAOHN J. 2009;57(12):497–504. doi:10.3928/08910162-20091116-01.Google Scholar
Garbarino, S, De Carli, F, Nobili, L, et al. Sleepiness and sleep disorders in shift workers: a study on a group of Italian police officers. Sleep. 2002;25(6):648–653. www.scopus.com/inward/record.uri?eid=2-s2.0-0037105031&partnerID=40&md5=ab041b7db1a8e5f30a104d7b96fe1b49. Accessed June 27, 2020.Google Scholar
Gan, Y, Yang, C, Tong, X, et al. Shift work and diabetes mellitus: a meta-analysis of observational studies. Occup Environ Med. 2015;72(1):72–78. doi:10.1136/oemed-2014-102150.Google Scholar
Ika, K, Suzuki, E, Mitsuhashi, T, Takao, S, Doi, H. Shift work and diabetes mellitus among male workers in Japan: does the intensity of shift work matter? Acta Med Okayama. 2013;67(1):25–33. doi:10.18926/AMO/49254.Google Scholar
Hansen, AB, Stayner, L, Hansen, J, Andersen, ZJ. Night shift work and incidence of diabetes in the Danish nurse cohort. Occup Environ Med. 2016;73(4):262–268. doi:10.1136/oemed-2015-103342.Google Scholar
Alefishat, E, Abu Farha, R. Is shift work associated with lipid disturbances and increased insulin resistance? Metab Syndr Relat Disord. 2015;13(9):400–405. doi:10.1089/met.2015.0052.CrossRefGoogle ScholarPubMed
Kawachi, I, Colditz, GA, Stampfer, MJ, et al. Prospective study of shift work and risk of coronary heart disease in women. Circulation. 1995;92(11):3178–3182. doi:10.1161/01.CIR.92.11.3178.Google Scholar
Vetter, C, Devore, EE, Wegrzyn, LR, et al. Association between rotating night shift work and risk of coronary heart disease among women. JAMA. 2016;315(16):1726–1734. doi:10.1001/jama.2016.4454.CrossRefGoogle ScholarPubMed
Ceïde, ME, Pandey, A, Ravenell, J, Donat, M, Ogedegbe, G, Girardin, JL. Associations of short sleep and shift work status with hypertension among black and white Americans. Int J Hypertens. 2015;2015:697275. doi:10.1155/2015/697275.Google Scholar
Ohlander, J, Keskin, M, Stork, J, Radon, K. Shift work and hypertension: prevalence and analysis of disease pathways in a German car manufacturing company. Am J Ind Med. 2015;58(5):549–560. doi:10.1002/ajim.22437.Google Scholar
Guo, Y, Liu, Y, Huang, X, et al. The effects of shift work on sleeping quality, hypertension and diabetes in retired workers. PLoS ONE. 2013;8(8):e71107. doi:10.1371/journal.pone.0071107.Google Scholar
Lee, HY, Kim, MS, Kim, O, Lee, I, Kim, H. Association between shift work and severity of depressive symptoms among female nurses: the Korea nurses’ health study. J Nurs Manag. 2016;24(2):192–200. doi:10.1111/jonm.12298.Google Scholar
Park, JN, Han, MA, Park, J, Ryu, SY. Prevalence of depressive symptoms and related factors in Korean employees: The third Korean working conditions survey (2011). Int J Environ Res Public Health. 2016;13(4):424. doi:10.3390/ijerph13040424.CrossRefGoogle ScholarPubMed
Deng, N, Kohn, TP, Lipshultz, LI, Pastuszak, AW. The relationship between shift work and men’s health. Sex Med Rev. 2018;6(3):446–456. doi:S2050-0521(17)30150-6.Google Scholar
Kohn, TP, Kohn, JR, Haney, NM, Pastuszak, AW, Lipshultz, LI. The effect of sleep on men’s health. Transl Androl Urol. 2020;9:S178–S185. doi:10.21037/tau.2019.11.07.Google Scholar
Feldman, HA, Irwin, G, Hatzichristou, DG, Krane, RJ, McKinlay, JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts male aging study. J Urol. 1994;151(1):54–61. doi:10.1016/S0022-5347(17)34871-1.Google Scholar
Saigal, CS, Wessells, H, Pace, J, Schonlau, M, Wilt, TJ. Predictors and prevalence of erectile dysfunction in a racially diverse population. Arch Intern Med. 2006;166(2):207–212. doi:10.1001/archinte.166.2.207.Google Scholar
American Academy of Sleep Medicine Taskforce. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. Sleep. 1999;22(5):667–689. doi:10.1093/sleep/22.5.667.Google Scholar
Margel, D, Cohen, M, Livne, PM, Pillar, G. Severe, but not mild, obstructive sleep apnea syndrome is associated with erectile dysfunction. Urology. 2004;63(3):545–549. doi:10.1016/j.urology.2003.10.016.CrossRefGoogle Scholar
Heruti, R, Shochat, T, Tekes-Manova, D, Ashkenazi, I, Justo, D. Association between erectile dysfunction and sleep disorders measured by self-assessment questionnaires in adult men. J Sex Med. 2005;2(4):543–550. doi:10.1111/j.1743-6109.2005.00072.x.CrossRefGoogle ScholarPubMed
Budweiser, S, Enderlein, S, Jörres, RA, et al. Sleep apnea is an independent correlate of erectile and sexual dysfunction. J Sex Med. 2009;6(11):3147–3157. doi:10.1111/j.1743-6109.2009.01372.x.Google Scholar
Teloken, PE, Smith, EB, Lodowsky, C, Freedom, T, Mulhall, JP. Defining association between sleep apnea syndrome and erectile dysfunction. Urology. 2006;67(5):1033–1037. doi:10.1016/j.urology.2005.11.040.CrossRefGoogle ScholarPubMed
Zheng, W, Chen, X, Huang, J, et al. Blood oxygen accumulation distribution area index is associated with erectile dysfunction in patients with sleep apnea: results from a cross-sectional study. Sex Med. 2020;8(1):36–44. doi:10.1016/j.esxm.2019.11.001.CrossRefGoogle ScholarPubMed
İrer, B, Çelikhisar, A, Çelikhisar, H, Bozkurt, O, Demir, Ö. Evaluation of sexual dysfunction, lower urinary tract symptoms and quality of life in men with obstructive sleep apnea syndrome and the efficacy of continuous positive airway pressure therapy. Urology. 2018;121:86–92. doi:10.1016/j.urology.2018.08.001.Google Scholar
Andersen, ML, Santos-Silva, R, Bittencourt, LRA, Tufik, S. Prevalence of erectile dysfunction complaints associated with sleep disturbances in Sao Paulo, Brazil: a population-based survey. Sleep Med. 2010;11(10):1019–1024. doi:10.1016/j.sleep.2009.08.016.Google Scholar
Kellesarian, SV, Malignaggi, VR, Feng, C, Javed, F. Association between obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis. Int J Impot Res. 2018;30(3):129–140. doi:10.1038/s41443-018-0017-7.CrossRefGoogle ScholarPubMed
Bozorgmehri, S, Fink, HA, Parimi, N, et al. Association of sleep disordered breathing with erectile dysfunction in community dwelling older men. J Urol. 2017;197(3):776–782. doi:10.1016/j.juro.2016.09.089.Google Scholar
Seehuus, M, Pigeon, W. The sleep and sex survey: relationships between sexual function and sleep. J Psychosom Res. 2018;112:59–65. doi:10.1016/j.jpsychores.2018.07.005.Google Scholar
Le, HH, Salas, RME, Gamaldo, A, et al. The utility and feasibility of assessing sleep disruption in a men’s health clinic using a mobile health platform device: a pilot study. Int J Clin Pract. 2018;72(1):e12999. doi:10.1111/ijcp.12999.Google Scholar
Soterio-Pires, JH, Hirotsu, C, Kim, LJ, Bittencourt, L, Tufik, S, Andersen, ML. The interaction between erectile dysfunction complaints and depression in men: a cross-sectional study about sleep, hormones and quality of life. Int J Impot Res. 2017;29(2):70–75. doi:10.1038/ijir.2016.49.Google Scholar
Gao, X, Schwarzschild, MA, O’Reilly, EJ, Wang, H, Ascherio, A. Restless legs syndrome and erectile dysfunction. Sleep. 2010;33(1):75–79. doi:10.1093/sleep/33.1.75.Google Scholar
Li, Y, Batool-Anwar, S, Kim, S, Rimm, EB, Ascherio, A, Gao, X. Prospective study of restless legs syndrome and risk of erectile dysfunction. Am J Epidemiol. 2013;177(10):1097–1105. doi:10.1093/aje/kws364.CrossRefGoogle ScholarPubMed
Pascual, M, Batlle, Jd, Barbé, F, et al. Erectile dysfunction in obstructive sleep apnea patients: a randomized trial on the effects of continuous positive airway pressure (CPAP). PLoS ONE. 2018;13(8):e0201930. doi:10.1371/journal.pone.0201930.Google Scholar
Jara, SM, Hopp, ML, Weaver, EM. Association of continuous positive airway pressure treatment with sexual quality of life in patients with sleep apnea: follow-up study of a randomized clinical trial. JAMA Otolaryngol Head Neck Surg. 2018;144(7):587–593. doi:10.1001/jamaoto.2018.0485.Google Scholar
Melehan, KL, Hoyos, CM, Hamilton, GS, et al. Randomized trial of CPAP and vardenafil on erectile and arterial function in men with obstructive sleep apnea and erectile dysfunction. J Clin Endocrinol Metab. 2018;103(4):1601–1611. doi:10.1210/jc.2017-02389.Google Scholar
Pastore, AL, Palleschi, G, Ripoli, A, et al. Severe obstructive sleep apnoea syndrome and erectile dysfunction: a prospective randomised study to compare sildenafil vs. nasal continuous positive airway pressure. Int J Clin Pract. 2014;68(8):995–1000. doi:10.1111/ijcp.12463.CrossRefGoogle ScholarPubMed
Li, Z, Fang, Z, Xing, N, Zhu, S, Fan, Y. The effect of CPAP and PDE5i on erectile function in men with obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis. Sleep Med Rev. 2019;48:101217. doi:S1087-0792(19)30185-6.Google Scholar
Pastuszak, AW, Moon, YM, Scovell, J, et al. Poor sleep quality predicts hypogonadal symptoms and sexual dysfunction in male nonstandard shift workers. Urology. 2017;102:121–125. doi:10.1016/j.urology.2016.11.033.CrossRefGoogle ScholarPubMed
Rodriguez, KM, Kohn, TP, Kohn, JR, et al. Pd27–06 shift work sleep disorder and night shift work significantly impair erectile function. J Urol. 2018;199(4):e559. doi:10.1016/j.juro.2018.02.1357.Google Scholar
Taylor, BC, Wilt, TJ, Fink, HA, et al. Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: the MrOS study. Urology. 2006;68(4):804–809. doi.10.1016/j.urology.2006.04.019.Google Scholar
Lepor, H. Pathophysiology of lower urinary tract symptoms in the aging male population. Rev Urol. 2005;7(Suppl. 7):S3–S11. www.ncbi.nlm.nih.gov/pubmed/16986059.Google Scholar
Bates, J, Kohn, T, Rodriguez, K, et al. Pd65–08: poor sleep quality is associated with clinically significant lower urinary tract symptoms. J Urol. 2019;201:e1189–e1190. doi:10.1097/01.JU.0000557582.48673.b0.Google Scholar
Martin, SA, Appleton, SL, Adams, RJ, et al. Nocturia, other lower urinary tract symptoms and sleep dysfunction in a community-dwelling cohort of men. Urology. 2016;97:219–226. doi.org/10.1016/j.urology.2016.06.022.CrossRefGoogle Scholar
Arslan, B, Gezmis, CT, Çetin, B, et al. Is obstructive sleep apnea syndrome related to nocturia? Low Urin Tract Symptoms. 2019;11(3):139–142. doi:10.1111/luts.12250.Google Scholar
Miyauchi, Y, Okazoe, H, Tamaki, M, et al. Obstructive sleep apnea syndrome as a potential cause of nocturia in younger adults. Urology. 2020;143:42–47. doi:10.1016/j.urology.2020.04.116.CrossRefGoogle ScholarPubMed
Everaert, K, Anderson, P, Wood, R, Andersson, FL, Holm-Larsen, T. Nocturia is more bothersome than daytime LUTS: results from an observational, real-life practice database including 8659 European and American LUTS patients. Int J Clin Pract. 2018;72(6):e13091. doi:10.1111/ijcp.13091.Google Scholar
Doo, SW, Lee, HJ, Ahn, J, et al. Strong impact of nocturia on sleep quality in patients with lower urinary tract symptoms. World J Mens Health. 2012;30(2):123–130. doi:10.5534/wjmh.2012.30.2.123.Google Scholar
Obayashi, K, Saeki, K, Kurumatani, N. Quantitative association between nocturnal voiding frequency and objective sleep quality in the general elderly population: the HEIJO-KYO cohort. Sleep Medicine. 2015;16(5):577–582. doi:10.1016/j.sleep.2015.01.021.Google Scholar
Fantus, RJ, Packiam, VT, Wang, CH, Erickson, BA, Helfand, BT. The relationship between sleep disorders and lower urinary tract symptoms: results from the NHANES. J Urol. 2018;200(1):161–166. doi:10.1016/j.juro.2018.01.083.Google Scholar
Miyauchi, Y, Okazoe, H, Okujyo, M, et al. Effect of the continuous positive airway pressure on the nocturnal urine volume or night-time frequency in patients with obstructive sleep apnea syndrome. Urology. 2015;85(2):333–336. doi:10.1016/j.urology.2014.11.002.CrossRefGoogle ScholarPubMed
Fernández-Pello, S, Gil, R, Escaf, S, et al. Síntomas de tramo urinario inferior y síndrome de apnea obstructiva del sueño: evolución urodinámica antes y después de un año de tratamiento con presión continua positiva de la vía aérea. Actas Urológicas Españolas. 2019;43(7):371–377. doi:10.1016/j.acuro.2019.03.004.Google Scholar
Park, HK, Paick, SH, Kim, HG, et al. Nocturia improvement with surgical correction of sleep apnea. Int Neurourol J. 2016;20(4):329–334. doi:10.5213/inj.1632624.312.Google Scholar
Shimizu, N, Nozawa, M, Sugimoto, K, et al. Therapeutic efficacy and anti-inflammatory effect of ramelteon in patients with insomnia associated with lower urinary tract symptoms. Res Rep Urol. 2013;5:113–119. doi:10.2147/RRU.S44502.Google ScholarPubMed
Takao, T, Tsujimura, A, Kiuchi, H, Takezawa, K, Nonomura, N, Miyagawa, Y. Improvement of nocturia and sleep disturbance by silodosin in male patients with lower urinary tract symptoms. Int J Urol. 2015;22(2):236–238. doi:10.1111/iju.12638.Google Scholar
Sakuma, T, Sato, K, Nagane, Y, et al. Effects of α1-blockers for lower urinary tract symptoms and sleep disorders in patients with benign prostatic hyperplasia. Lower Urin Tract Symptoms. 2010;2(2):119–122. doi:10.1111/j.1757-5672.2010.00073.x.CrossRefGoogle ScholarPubMed
Kim, JW. Effect of shift work on nocturia. Urology. 2016;87:153–160. doi:10.1016/j.urology.2015.07.047.Google Scholar
Sigalos, JT, Kohn, TP, Cartagenova, L, et al. Shift workers with shift work disorder have worse lower urinary tract symptoms. Urology. 2019;128:66–70. doi:10.1016/j.urology.2019.02.025.Google Scholar
Scovell, JM, Pastuszak, AW, Slawin, J, Badal, J, Link, RE, Lipshultz, LI. Impaired sleep quality is associated with more significant lower urinary tract symptoms in male shift workers. Urology. 2017;99:197–202. doi:10.1016/j.urology.2016.05.076.Google Scholar
Branche, BL, Howard, LE, Moreira, DM, et al. Sleep problems are associated with development and progression of lower urinary tract symptoms: results from REDUCE. J Urol. 2018;199(2):536–542. doi:10.1016/j.juro.2017.08.108.Google Scholar
Araujo, AB, Yaggi, HK, Yang, M, McVary, KT, Fang, SC, Bliwise, DL. Sleep related problems and urological symptoms: testing the hypothesis of bidirectionality in a longitudinal, population based study. J Urol. 2014;191(1):100–106. doi:S0022-5347(13)04886-6.Google Scholar
Fukunaga, A, Kawaguchi, T, Funada, S, et al. Sleep disturbance worsens lower urinary tract symptoms: the Nagahama study. J Urol. 2019;202(2):354. doi:10.1097/JU.0000000000000212.Google Scholar
Mulhall, JP, Trost, LW, Brannigan, RE, et al. Evaluation and management of testosterone deficiency: AUA guideline. J Urol. 2018;200(2):423–432. doi:S0022-5347(18)42817-0.Google Scholar
Evans, JI, MacLean, AW, Ismail, AA, Love, D. Concentrations of plasma testosterone in normal men during sleep. Nature. 1971;229(5282):261–262. doi:10.1038/229261a0.Google Scholar
Åkerstedt, T, Palmblad, J, de la Torre, B, Marana, R, Gillberg, M. Adrenocortical and gonadal steroids during sleep deprivation. Sleep. 1980;3(1):23–30. doi:10.1093/sleep/3.1.23.Google Scholar
Cortés-Gallegos, V, Castañeda, G, Alonso, R, et al. Sleep deprivation reduces circulating androgens in healthy men. Arch Androl. 1983;10(1):33–37. doi:10.3109/01485018308990167.Google Scholar
González-Santos, MR, Gajá-Rodríguez, OV, Alonso-Uriarte, R, Sojo-Aranda, I, Cortés-Gallegos, V. Sleep deprivation and adaptive hormonal responses of healthy men. Arch Androl. 1989;22(3):203–207. doi:10.3109/01485018908986773.Google Scholar
Leproult, R, Van Cauter, E. Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA. 2011;305(21):2173–2174. doi:10.1001/jama.2011.710.Google Scholar
Smith, I, Salazar, I, RoyChoudhury, A, St-Onge, MP. Sleep restriction and testosterone concentrations in young healthy males: randomized controlled studies of acute and chronic short sleep. Sleep Health. 2019;5(6):580–586. doi:S2352-7218(19)30139-1.Google Scholar
Jauch-Chara, K, Schmid, SM, Hallschmid, M, Oltmanns, KM, Schultes, B. Pituitary-gonadal and pituitary-thyroid axis hormone concentrations before and during a hypoglycemic clamp after sleep deprivation in healthy men. PLoS ONE. 2013;8(1):e54209. doi:10.1371/journal.pone.0054209.CrossRefGoogle ScholarPubMed
Arnal, PJ, Drogou, C, Sauvet, F, et al. Effect of sleep extension on the subsequent testosterone, cortisol and prolactin responses to total sleep deprivation and recovery. J Neuroendocrinol. 2016;28(2). doi:10.1111/jne.12346.Google Scholar
Luboshitzky, R, Zabari, Z, Shen-Orr, Z, Herer, P, Lavie, P. Disruption of the nocturnal testosterone rhythm by sleep fragmentation in normal men. J Clin Endocrinol Metab. 2001;86(3):1134–1139. doi:10.1210/jcem.86.3.7296.Google Scholar
Reynolds, AC, Dorrian, J, Liu, PY, et al. Impact of five nights of sleep restriction on glucose metabolism, leptin and testosterone in young adult men. PLoS ONE. 2012;7(7):e41218. doi:10.1371/journal.pone.0041218.Google Scholar
Schmid, SM, Hallschmid, M, Jauch-Chara, K, Lehnert, H, Schultes, B. Sleep timing may modulate the effect of sleep loss on testosterone. Clin Endocrinol (Oxf). 2012;77(5):749–754. doi:10.1111/j.1365-2265.2012.04419.x.Google Scholar
Patel, P, Shiff, B, Kohn, TP, Ramasamy, R. Impaired sleep is associated with low testosterone in US adult males: results from the National Health and Nutrition Examination Survey. World J Urol. 2019;37(7):1449–1453. doi:10.1007/s00345-018-2485-2.CrossRefGoogle ScholarPubMed
Penev, PD. Association between sleep and morning testosterone levels in older men. Sleep. 2007;30(4):427–432. doi:10.1093/sleep/30.4.427.CrossRefGoogle ScholarPubMed
Du, C, Yang, Y, Chen, J, Feng, L, Lin, W. Association between sleep quality and semen parameters and reproductive hormones: a cross-sectional study in Zhejiang, China. Nat Sci Sleep. 2020;12:11–18. doi:10.2147/NSS.S235136.Google Scholar
Mohammadi, H, Rezaei, M, Sharafkhaneh, A, Khazaie, H, Ghadami, MR. Serum testosterone/cortisol ratio in people with obstructive sleep apnea. J Clin Lab Anal. 2020;34(1):e23011. doi:10.1002/jcla.23011.Google Scholar
Mohammadi, H, Rezaei, M, Faghihi, F, Khazaie, H. Hypothalamic–pituitary–gonadal activity in paradoxical and psychophysiological insomnia. J Med Signals Sens. 2019;9(1):59–67. doi:10.4103/jmss.JMSS_31_18.Google Scholar
Auyeung, TW, Kwok, T, Leung, J, et al. Sleep duration and disturbances were associated with testosterone level, muscle mass, and muscle strength: a cross-sectional study in 1274 older men. J Am Med Dir Assoc. 2015;16(7):630.e1–630.e6. doi:S1525-8610(15)00294-7.Google Scholar
Brigette, MC, Andrew, DV, Martin, S, et al. Obstructive sleep apnea is not an independent determinant of testosterone in men. Eur J Endocrinol. 2020;183(1):31–39. doi:10.1530/EJE-19-0978.Google Scholar
Wittert, G. The relationship between sleep disorders and testosterone in men. Asian J Androl. 2014;16(2):262–265. doi:10.4103/1008-682X.122586.Google Scholar
Touitou, Y, Motohashi, Y, Reinberg, A, et al. Effect of shift work on the night-time secretory patterns of melatonin, prolactin, cortisol and testosterone. Eur J Appl Physiol Occup Physiol. 1990;60(4):288–292. doi:10.1007/BF00379398.Google Scholar
Axelsson, J, Åkerstedt, T, Kecklund, G, Lindqvist, A, Attefors, R. Hormonal changes in satisfied and dissatisfied shift workers across a shift cycle. J Appl Physiol. 2003;95(5):2099–2105. doi:10.1152/japplphysiol.00231.2003.Google Scholar
Smith, AM, Morris, P, Rowell, KO, Clarke, S, Jones, TH, Channer, KS. Junior doctors and the full shift rota – psychological and hormonal changes: a comparative cross-sectional study. Clin Med. 2006;6(2):174–177. doi:10.7861/clinmedicine.6-2-174.Google Scholar
Jensen, MA, Hansen, ÅM, Kristiansen, J, Nabe-Nielsen, K, Garde, AH. Changes in the diurnal rhythms of cortisol, melatonin, and testosterone after 2, 4, and 7 consecutive night shifts in male police officers. Chronobiol Int. 2016;33(9):1280–1292. doi:10.1080/07420528.2016.1212869.Google Scholar
Charlier, CM, Barr, ML, Colby, SE, Greene, GW, Olfert, MD. Correlations of self-reported androgen deficiency in ageing males (ADAM) with stress and sleep among young adult males. Healthcare (Basel, Switzerland). 2018;6(4):121. doi:10.3390/healthcare6040121.Google Scholar
Balasubramanian, A, Kohn, TP, Santiago, JE, et al. Increased risk of hypogonadal symptoms in shift workers with shift work sleep disorder. Urology. 2020;138:52–59. doi:10.1016/j.urology.2019.10.040.Google Scholar
Morley, JE, Charlton, E, Patrick, P, et al. Validation of a screening questionnaire for androgen deficiency in aging males. Metabolism. 2000;49(9):1239–1242. doi:S0026-0495(00)25964-7.CrossRefGoogle ScholarPubMed
Jarow, JP, Sharlip, ID, Belker, AM, et al. Best practice policies for male infertility. J Urol. 2002;167(5):2138–2144. doi:S0022-5347(05)65109-9.Google Scholar
Wise, LA, Rothman, KJ, Wesselink, AK, et al. Male sleep duration and fecundability in a North American preconception cohort study. Fertil Steril. 2018;109(3):453–459. doi:10.1016/j.fertnstert.2017.11.037.Google Scholar
Kohn, TP, Pastuszak, A. Shift work is associated with altered semen parameters in infertile men. Fertil Steril. 2017;108(3):E323–E324. doi:10.1016/j.fertnstert.2017.07.956.Google Scholar
Jensen, TK, Andersson, A, Skakkebæk, NE, et al. Association of sleep disturbances with reduced semen quality: a cross-sectional study among 953 healthy young Danish men. Am J Epidemiol. 2013;177(10):1027–1037. doi:10.1093/aje/kws420.Google Scholar
Chen, Q, Yang, H, Zhou, N, et al. Inverse U-shaped association between sleep duration and semen quality: longitudinal observational study (MARHCS) in Chongqing, China. Sleep. 2016;39(1):79–86. doi:10.5665/sleep.5322.Google Scholar
Wang, X, Chen, Q, Zou, P, et al. Sleep duration is associated with sperm chromatin integrity among young men in Chongqing, China. J Sleep Res. 2018;27(4):e12615. doi:10.1111/jsr.12615.Google Scholar
Hvidt, JEM, Knudsen, UB, Zachariae, R, Ingerslev, HJ, Philipsen, MT, Frederiksen, Y. Associations of bedtime, sleep duration, and sleep quality with semen quality in males seeking fertility treatment: a preliminary study. Basic Clin Androl. 2020;30:5–7. doi:10.1186/s12610-020-00103-7.Google Scholar
Liu, MM, Liu, L, Chen, L, et al. Sleep deprivation and late bedtime impair sperm health through increasing antisperm antibody production: a prospective study of 981 healthy men. Med Sci Monit. 2017;23:1842–1848. doi:10.12659/msm.900101.Google Scholar
Green, A, Barak, S, Shine, L, Kahane, A, Dagan, Y. Exposure by males to light emitted from media devices at night is linked with decline of sperm quality and correlated with sleep quality measures. Chronobiol Int. 2020;37(3):414–424. doi:10.1080/07420528.2020.1727918.CrossRefGoogle ScholarPubMed
Chen, H, Sun, B, Chen, Y, et al. Sleep duration and quality in relation to semen quality in healthy men screened as potential sperm donors. Environ Int. 2020;135:105368. doi:10.1016/j.envint.2019.105368.CrossRefGoogle ScholarPubMed
Bisanti, L, Olsen, J, Basso, O, Thonneau, P, Karmaus, W. The European Study Group on Infertility, and Subfecundity. Shift work and subfecundity: a European multicenter study. J Occup Environ Med. 1996;38(4):352–358. doi:10.1097/00043764-199604000-00012.Google Scholar
Tuntiseranee, P, Olsen, J, Geater, A, Kor-anantakul, O. Are long working hours and shiftwork risk factors for subfecundity? A study among couples from Southern Thailand. Occup Environ Med. 1998;55(2):99–105. doi:10.1136/oem.55.2.99.Google Scholar
El-Helaly, M, Awadalla, N, Mansour, M, El-Biomy, Y. Workplace exposures and male infertility: a case-control study. Int J Occup Med Environ Health. 2010;23(4):331–338. doi:10.2478/v10001-010-0039-y.Google Scholar
Eisenberg, ML, Chen, Z, Ye, A, Buck Louis, GM. Relationship between physical occupational exposures and health on semen quality: data from the Longitudinal Investigation of Fertility and the Environment (LIFE) study. Fertil Steril. 2015;103(5):1271–1277. doi:10.1016/j.fertnstert.2015.02.010.Google Scholar
Palnitkar, G, Phillips, CL, Hoyos, CM, Marren, AJ, Bowman, MC, Yee, BJ. Linking sleep disturbance to idiopathic male infertility. Sleep Med Rev. 2018;42:149–159. doi:10.1016/j.smrv.2018.07.006.Google Scholar
Rossi, SP, Windschuettl, S, Matzkin, ME, et al. Melatonin in testes of infertile men: evidence for anti‐proliferative and anti‐oxidant effects on local macrophage and mast cell populations. Andrology. 2014;2(3):436–449. doi:10.1111/j.2047-2927.2014.00207.x.Google Scholar
Bejarano, I, Monllor, F, Marchena, AM, et al. Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa. J Pineal Res. 2014;57(3):333–339. doi:10.1111/jpi.12172.Google Scholar
Colten, HR, Altevogt, BM, Institute of Medicine (US) Committee on Sleep Medicine and Research. Extent and health consequences of chronic sleep loss and sleep disorders. In: Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. National Academies Press; 2006. www.ncbi.nlm.nih.gov/books/NBK19961/. Accessed July 2, 2020.Google Scholar
Walia, AS, Lomeli, LJM, Jiang, P, Benca, R, Yafi, FA. Patients presenting to a men’s health clinic are at higher risk for depression, insomnia, and sleep apnea. Int J Impotence Res. 2019;31(1):39–45. doi:10.1038/s41443-018-0057-z.Google Scholar
Kalejaiye, O, Raheem, AA, Moubasher, A, et al. Sleep disorders in patients with erectile dysfunction. BJU Int. 2017;120(6):855–860. doi:10.1111/bju.13961.Google Scholar
Pataka, A, Daskalopoulou, E, Kalamaras, G, Fekete Passa, K, Argyropoulou, P. Evaluation of five different questionnaires for assessing sleep apnea syndrome in a sleep clinic. Sleep Med. 2014;15(7):776–781. doi:S1389-9457(14)00147-6.Google Scholar
Chung, F, Abdullah, HR, Liao, P. STOP-Bang questionnaire: a practical approach to screen for obstructive sleep apnea. Chest. 2016;149(3):631–638. doi:10.1378/chest.15-0903.Google Scholar
Kim, SD, Cho, KS. Obstructive sleep apnea and testosterone deficiency. W J Mens Health. 2019;37(1):12–18. doi:10.5534/wjmh.180017.Google Scholar
Buysse, DJ, Reynolds, CF, Monk, TH, Berman, SR, Kupfer, DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213. doi:10.1016/0165-1781(89)90047-4.Google Scholar
Irish, LA, Kline, CE, Gunn, HE, Buysse, DJ, Hall, MH. The role of sleep hygiene in promoting public health: a review of empirical evidence. Sleep Med Rev. 2015;22:23–36. doi:10.1016/j.smrv.2014.10.001.Google Scholar
Bates, J, Kohn, T, Rodriguez, K, et al. PD65–08 poor sleep quality is associated with clinically significant lower urinary tract symptoms. J Urol. 2019;201:1189–1190. doi:10.21037/tau.2019.11.07.Google Scholar
Kohn, TP, Rodriguez, KM, Sigalos, JT, et al. PD27–08 poor sleep quality is associated with clinically significant erectile dysfunction. J Urol. 2018;199:e560. doi:10.1016/j.juro.2018.02.1359.Google Scholar

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