Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-27T10:02:41.715Z Has data issue: false hasContentIssue false

Chapter 38 - Lifestyle Modifications for Erectile Dysfunction

from Section 5 - Medical and Surgical Management of Issues of Male Health

Published online by Cambridge University Press:  06 December 2023

By
Jeffrey S. Edman ,
Jade Warner  and
Amy M. Pearlman
Edited by
Douglas T. Carrell ,
Alexander W. Pastuszak  and
James M. Hotaling
Douglas T. Carrell
Affiliation:
Utah Center for Reproductive Medicine
Alexander W. Pastuszak
Affiliation:
University of Utah
James M. Hotaling
Affiliation:
Utah Center for Reproductive Medicine
Get access

Summary

Sexual health and, specifically, erectile function play an important role in the lives of many men. Lifestyle modification, considered first-line therapy for many disease processes, is often overlooked and underdiscussed, particularly with the advent of pharmacologic and surgical interventions to restore erectile function. Even though these medical and surgical interventions are highly successful, discussion of lifestyle modification for prevention of erectile dysfunction, as solo therapy, or as adjunct to other therapies, still plays a role in the armamentarium of the healthcare provider. The aim of our chapter is to review the literature assessing impact of lifestyle modification on erectile function.

Keywords

lifestyle modificationerectile dysfunctionnitric oxidereactive oxygen speciescytokinesinflammation
Type
Chapter
Information
Men's Reproductive and Sexual Health Throughout the Lifespan
An Integrated Approach to Fertility, Sexual Function, and Vitality
 , pp. 303 - 307
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Selvin, E, Burnett, AL, Platz, EA. Prevalence and risk factors for erectile dysfunction in the US. Am J Med. 2007;120(2):151–157.Google Scholar
Laumann, EO, Paik, A, Rosen, RC. Sexual dysfunction in the United States. JAMA. 1999;281(6):537–544.Google Scholar
Derby, CA, et al. Modifiable risk factors and erectile dysfunction: can lifestyle changes modify risk? Urology. 2000;56(2):302–306.Google Scholar
Wentzell, E, Salmerón, J. You’ll “get Viagraed”: Mexican men’s preference for alternative erectile dysfunction treatment. Soc Sci Med. 2009;68(10):1759–1765.Google Scholar
Arnold, DG, Oakley, JL. Self-regulation in the pharmaceutical industry: the exposure of children and adolescents to erectile dysfunction commercials. J Health Polit Policy Law. 2019;44(5):765–787.Google Scholar
Rajfer, J, et al. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. N Engl J Med. 1992;326(2):90–94.Google Scholar
Meldrum, DR, et al. The link between erectile and cardiovascular health: the canary in the coal mine. Am J Cardiol. 2011;108(4):599–606.CrossRefGoogle ScholarPubMed
Flammer, AJ, et al. Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension. J Hypertens. 2007;25(4):785–791.Google Scholar
Zuo, Z, et al. Effect of periodontitis on erectile function and its possible mechanism. J Sex Med. 2011;8(9):2598–2605.Google Scholar
Giugliano, F, et al. Erectile dysfunction associates with endothelial dysfunction and raised proinflammatory cytokine levels in obese men. J Endocrin Invest. 2004;27(7):665–669.CrossRefGoogle ScholarPubMed
Yudkin, JS, et al. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction. Arterioscler Thromb Vasc Biol. 1999;19(4):972–978.CrossRefGoogle ScholarPubMed
Koskimäki, J, et al. Regular intercourse protects against erectile dysfunction: Tampere Aging Male Urologic Study. Am J Med. 2008;121(7):592–596.Google Scholar
Gerbild, H, et al. Physical activity to improve erectile function: a systematic review of intervention studies. Sex Med. 2018;6(2):75–89.Google Scholar
Rosen, RC, et al. The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49(6):822–830.CrossRefGoogle ScholarPubMed
He, F, et al. Redox mechanism of reactive oxygen species in exercise. Front Physiol. 2016;7:486.Google Scholar
Dorey, G, et al. Pelvic floor exercises for erectile dysfunction. BJU Int. 2005;96(4):595–597.Google Scholar
Dorey, G, et al. Pelvic floor exercises for treating post-micturition dribble in men with erectile dysfunction: a randomized controlled trial. Urol Nurs. 2004;24(6):490–497, 512.Google Scholar
Marseglia, L, et al. Oxidative stress in obesity: a critical component in human diseases. Int J Mol Sci. 2014;16(1):378–400.Google Scholar
Russo, GI, et al. Insulin resistance is an independent predictor of severe lower urinary tract symptoms and of erectile dysfunction: results from a cross‐sectional study. J Sex Med. 2014;11(8):2074–2082.Google Scholar
Esposito, K, et al. Effect of lifestyle changes on erectile dysfunction in obese men. JAMA. 2004;291(24):2978–2984.Google Scholar
Esposito, K, et al. Effect of a single high-fat meal on endothelial function in patients with the metabolic syndrome: role of tumor necrosis factor-α. Nutr Metab Cardiovasc Dis. 2007;17(4):274–279.CrossRefGoogle ScholarPubMed
Malavige, LS, Levy, JC. Erectile dysfunction in diabetes mellitus. J Sex Med. 2009;6(5):1232–1247.Google Scholar
Tostes, RC, et al. Cigarette smoking and erectile dysfunction: focus on NO bioavailability and ROS generation. J Sex Med. 2008;5(6):1284–1295.Google Scholar
Kovac, JR, et al. Effects of cigarette smoking on erectile dysfunction. Andrologia. 2015;47(10):1087–1092.Google Scholar
Abou-Agag, LH, et al. Evidence of cardiovascular protection by moderate alcohol: role of nitric oxide. Free Radic Biol Med. 2005;39(4):540–548.Google Scholar
Ignarro, LJ, et al. Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide. Nitric Oxide. 2006;15(2):93–102.Google Scholar
Peluffo, G, et al. Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers. Am J Physiol Heart Circ Physiol. 2009;296(6):H1781–H1792.Google Scholar
Atkeson, A, et al. Endothelial function in obstructive sleep apnea. Prog Cardiovasc Dis. 2009;51(5):351–362.Google Scholar
Pascual, M, et al. Erectile dysfunction in obstructive sleep apnea patients: a randomized trial on the effects of continuous positive airway pressure (CPAP). PLoS ONE. 2018;13(8):e0201930.Google Scholar
İrer, B, et al. Evaluation of sexual dysfunction, lower urinary tract symptoms and quality of life in men with obstructive sleep apnea syndrome and the efficacy of continuous positive airway pressure therapy. Urology. 2018;121:86–92.Google Scholar
Hoekema, A, et al. Sexual function and obstructive sleep apnea–hypopnea: a randomized clinical trial evaluating the effects of oral-appliance and continuous positive airway pressure therapy. J Sex Med. 2007;4(4):1153–1162.Google Scholar
Litwin, MS, Nied, RJ, Dhanani, N. Health-related quality of life in men with erectile dysfunction. J Gen Intern Med. 1998;13(3):159–166.Google Scholar
Aghighi, A, Grigoryan, VH, Delavar, A. Psychological determinants of erectile dysfunction among middle-aged men. Int J Impot Res. 2015;27(2):63–68.Google Scholar
Lee, JC, et al. The prevalence and influence of significant psychiatric abnormalities in men undergoing comprehensive management of organic erectile dysfunction. Int J Impot Res. 2000;12(1):47–51.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×