Book contents
- Marijuana and Madness
- Marijuana and Madness
- Copyright page
- Contents
- Contributors
- Preface
- 1 How cannabis works in the brain
- 2 Other cannabinoids
- 3 The function of the endocannabinoid system
- 4 Is cannabis becoming more potent?
- 5 What are the policy implications of the evidence on cannabis and psychosis?
- 6 Cannabis, endocannabinoids and neurodevelopment
- 7 The impact of pubertal exposure to cannabis on the brain: a focus on animal studies
- 8 Cannabis and cognition: short- and long-term effects
- 9 Does cannabis cause lasting brain damage?
- 10 The association between cannabis use and depression: a review of the evidence
- 11 Cannabis, cannabinoids and bipolar disorder
- 12 Which cannabis users develop psychosis?
- 13 Cannabinoids and the cerebellum: a potential role in the development of psychosis
- 14 The neural basis for the acute effects of cannabis on learning and psychosis
- 15 Does cannabis use cause schizophrenia? The epidemiological evidence
- 16 Postmortem studies of the brain cannabinoid system in schizophrenia
- 17 The endocannabinoid system in schizophrenia
- 18 The acute effects of cannabinoids in patients with psychotic illness
- 19 Cannabis abuse and the course of schizophrenia
- 20 Understanding cannabis use in schizophrenia
- 21 Addressing cannabis use in people with psychosis
- Index
18 - The acute effects of cannabinoids in patients with psychotic illness
Published online by Cambridge University Press: 05 November 2011
Book contents
- Marijuana and Madness
- Marijuana and Madness
- Copyright page
- Contents
- Contributors
- Preface
- 1 How cannabis works in the brain
- 2 Other cannabinoids
- 3 The function of the endocannabinoid system
- 4 Is cannabis becoming more potent?
- 5 What are the policy implications of the evidence on cannabis and psychosis?
- 6 Cannabis, endocannabinoids and neurodevelopment
- 7 The impact of pubertal exposure to cannabis on the brain: a focus on animal studies
- 8 Cannabis and cognition: short- and long-term effects
- 9 Does cannabis cause lasting brain damage?
- 10 The association between cannabis use and depression: a review of the evidence
- 11 Cannabis, cannabinoids and bipolar disorder
- 12 Which cannabis users develop psychosis?
- 13 Cannabinoids and the cerebellum: a potential role in the development of psychosis
- 14 The neural basis for the acute effects of cannabis on learning and psychosis
- 15 Does cannabis use cause schizophrenia? The epidemiological evidence
- 16 Postmortem studies of the brain cannabinoid system in schizophrenia
- 17 The endocannabinoid system in schizophrenia
- 18 The acute effects of cannabinoids in patients with psychotic illness
- 19 Cannabis abuse and the course of schizophrenia
- 20 Understanding cannabis use in schizophrenia
- 21 Addressing cannabis use in people with psychosis
- Index
Summary
This chapter reviews the acute effects of cannabis and cannabinoids in people with psychotic illness. The acute effects of cannabis in schizophrenia patients are reported to include no effects, reductions in anxiety, depression and negative symptoms, increased suspiciousness and variable effects on hallucinations. Tetrahydrocannibinol (THC) transiently exacerbated a range of positive and negative psychotic symptoms, perceptual alternations, cognitive deficits and medication side effects associated with schizophrenia without producing clear beneficial effects. Cannabidiol has been shown to have anxiolytic and antipsychotic effects, leading to the suggestion that cannabidiol may offset some of the adverse effects of THC. In patients with psychotic illness, cannabidiol appears to act like an antipsychotic. Cannabis use and misuse is common in people with schizophrenia. Ongoing clinical trials are likely to provide more definitive evidence regarding the effects of cannabidiol in schizophrenia.
- Type
- Chapter
- Information
- Marijuana and Madness , pp. 198 - 209Publisher: Cambridge University PressPrint publication year: 2011