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1.02 - Use of Plasma Levels in Antipsychotic and Mood Stabilizer Treatment

from Part I - Treatment Strategies

Published online by Cambridge University Press:  19 October 2021

Edited by
Michael Cummings  and
Stephen Stahl
Michael Cummings
Affiliation:
University of California, Los Angeles
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Antipsychotic medications represent the pharmacological foundation for the treatment of psychosis and psychomotor agitation. While antipsychotics may be prescribed based on accepted dose ranges, as well as patient response and tolerability, measuring plasma concentrations of antipsychotic medications now represents the standard of care [1].

Type
Chapter
Information
Management of Complex Treatment-resistant Psychotic Disorders , pp. 12 - 15
Publisher: Cambridge University Press
Print publication year: 2021

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References

Schoretsanitis, G., Kane, J. M., Correll, C. U., et al. (2020). Blood levels to optimize antipsychotic treatment in clinical practice: a joint consensus statement of the American Society of Clinical Psychopharmacology and the Therapeutic Drug Monitoring Task Force of the Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie. J Clin Psychiatry, 81(3), 19CS13169.CrossRefGoogle ScholarPubMed
Meyer, J. M. (2014). A rational approach to employing high plasma levels of antipsychotics for violence associated with schizophrenia: case vignettes. CNS Spectr, 19, 432–438.CrossRefGoogle ScholarPubMed
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Castro, V. M., Roberson, A. M., McCoy, T. H., et al. (2016). Stratifying risk for renal insufficiency among lithium-treated patients: an electronic health record study. Neuropsychopharmacol, 41, 1138–1143.CrossRefGoogle ScholarPubMed
Meyer, J. M. (2018). Gilman: The Pharmacological Basis of Therapeutics. Pharmacotherapy of Psychosis and Mania. New York: McGraw-Hill.Google Scholar
Letmaier, M., Painold, A., Holl, A. K., et al. (2012). Hyponatraemia during psychopharmacological treatment: results of a drug surveillance programme. Int J Neuropsychopharmacol, 15, 739–748.CrossRefGoogle ScholarPubMed
Kim, Y-S., Kim, D. W., Jung, K-H., et al. (2014). Frequency of and risk factors for oxcarbazepine-induced severe and symptomatic hyponatremia. Seizure, 23, 208–212.CrossRefGoogle ScholarPubMed

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