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Chapter 3 - Chromosome Abnormalities and the Infertile Male

Published online by Cambridge University Press:  24 May 2020

By
Csilla Krausz  and
Viktória Rosta
Edited by
R. John Aitken ,
David Mortimer  and
Gabor Kovacs
R. John Aitken
Affiliation:
University of Newcastle, New South Wales
David Mortimer
Affiliation:
Oozoa Biomedical Inc, Vancouver
Gabor Kovacs
Affiliation:
Epworth Healthcare Melbourne
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Summary

Male infertility is a highly heterogeneous, multifactorial, complex pathology of the reproductive system, affecting approximately 7% of the general male population. Genetic factors are estimated to contribute to nearly 20–25% of severe male infertility cases and inversely correlate with sperm production [1]. In fact, their frequency is 0.4% of the general population, while patients with a spermatozoa count of less than 5 million/ml already show a 10-fold higher incidence (4%) [2].

Type
Chapter
Information
Male and Sperm Factors that Maximize IVF Success , pp. 28 - 40
Publisher: Cambridge University Press
Print publication year: 2020

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