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Chapter 26 - Deep Brain Stimulation in Parkinson’s Disease

from Section 2: - Hypokinetic Movement Disorders

Published online by Cambridge University Press:  07 January 2025

By
Andres Lozano ,
Alfonso Fasano  and
Lennart H. Stieglitz
Edited by
Erik Ch. Wolters  and
Christian R. Baumann
Erik Ch. Wolters
Affiliation:
Universität Zürich
Christian R. Baumann
Affiliation:
Universität Zürich
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Summary

Deep brain stimulation (DBS) is one of the most effective tools in the treatment of Parkinson’s disease. Being a last-resort therapy for many years, it recently advanced to a valuable option in moderate and even earlier stages. Different nuclei of the basal ganglia have been successfully targeted with various effects, risks and stimulation-induced side effects. Advances in implantation technique and accuracy, neuroimaging and implant technology helped make DBS a mostly safe and successful procedure, although the full potential of recent technical advantages such as directional stimulation, brain sensing or remote programming have yet to be fully explored.

Keywords

Vim/STN/GPi/PPN brain stimulation targetstreatment/target selectionsurgical techniquesfuture advances
Type
Chapter
Information
International Compendium of Movement Disorders , pp. 316 - 327
Publisher: Cambridge University Press
Print publication year: 2025

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