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3.3.4 - Portal Hypertension

from Section 3.3 - Acute Liver Failure

Published online by Cambridge University Press:  27 July 2023

By
Michael Spiro  and
Jeremy Fabes
Edited by
Ned Gilbert-Kawai ,
Debashish Dutta  and
Carl Waldmann
Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
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Summary

Key Learning Points

  1. 1. Common causes include cirrhosis, venous obstruction and (worldwide) schistosomiasis.

  2. 2. High portal venous pressures may cause ascites and bleeding from variceal sites.

  3. 3. Management is of the underlying cause and complications of portal pressures.

  4. 4. Portal gastropathy is common but rarely causes acute haemorrhage.

  5. 5. Transjugular portosystemic shunting can decompress the portal system.

Keywords

transjugular portosystemic shuntinggastrointestinal bleedinggastropathy
Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
 , pp. 168 - 170
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Further Reading

Buob, S, Johnston, AN, Webster, CR. Portal hypertension: pathophysiology, diagnosis, and treatment. J Vet Intern Med 2011;25:169–86.CrossRefGoogle ScholarPubMed
Iwakiri, Y. Pathophysiology of portal hypertension. Clin Liver Dis 2014;18:281–91.CrossRefGoogle ScholarPubMed
Leung, JC, Loong, TC, Pang, J, Wei, JL, Wong, VW. Invasive and non-invasive assessment of portal hypertension. Hepatol Int 2018;12(Suppl 1):44–55.CrossRefGoogle ScholarPubMed
Strunk, H, Marinova, M. Transjugular intrahepatic portosystemic shunt (TIPS): pathophysiologic basics, actual indications and results with review of the literature. Rofo 2018;190:701–11.Google ScholarPubMed

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