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7.4 - Intensive Care Unit-Acquired Weakness and Physical Rehabilitation

from Section 7 - Comfort and Recovery

Published online by Cambridge University Press:  27 July 2023

Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
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Summary

Key Learning Points

  1. 1. Around 40 per cent of patients develop clinically detectable muscle weakness known as intensive care unit-acquired weakness (ICU-AW) that can lead to long-term functional deficit.

  2. 2. Accurate diagnosis of ICU-AW can be achieved through nerve conduction studies, electromyography, muscle biopsy and ultrasound of muscle cross-sectional area; however, more commonly, a clinical diagnosis is made using the Medical Research Council (MRC) Sum Score of muscle strength.

  3. 3. Prevention and timely management of sepsis is the optimal way to mitigate the risk of ICU-AW.

  4. 4. Minimising sedation, optimising pain relief, encouraging spontaneous breathing, early mobility and family engagement are the foundations of best quality care.

  5. 5. Rehabilitation should start early after admission to the intensive care unit and continue to at least 3 months after hospital discharge.

Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
, pp. 663 - 665
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Further Reading

National Institute for Health and Care Excellence. 2017. Rehabilitation after critical illness in adults. Quality standard [QS158]. www.nice.org.uk/guidance/qs158Google Scholar
Puthucheary, ZA, Rawal, J, McPhail, M, et al. Acute skeletal muscle wasting in critical illness. JAMA 2013;310:1591–600.CrossRefGoogle ScholarPubMed
Schaller, S, Anstey, M, Blobner, M, et al. Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial. Lancet 2016;388:1377–88.CrossRefGoogle ScholarPubMed
Society of Critical Care Medicine. 2018. ICU Liberation Bundle (A–F). www.sccm.org/ICULiberation/ABCDEF-BundlesGoogle Scholar
Wright, SE, Thomas, K, Watson, G, et al. Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial. Thorax 2017;73:213–21.Google ScholarPubMed

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