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Chapter 25 - Laser Interstitial Thermal Therapy (LITT) for Insular Epilepsy

from Section 5 - Surgical Management of Insular Epilepsy

Published online by Cambridge University Press:  09 June 2022

By
Azeem A. Rehman ,
Mark R. Lee  and
Dave F. Clarke
Edited by
Dang Nguyen ,
Jean Isnard  and
Philippe Kahane
Dang Nguyen
Affiliation:
Université de Montréal
Jean Isnard
Affiliation:
Claude Bernard University Lyon
Philippe Kahane
Affiliation:
Grenoble-Alpes University Hospital
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Summary

Compared to surgery, LITT provides minimal disruption of the brain matter, less post-operative pain and shorter length of stay. LITT has enabled a more minimalist approach to deep-seated targets such as the insula. Increasing utilization of stereoelectroencephalography has allowed for better identification of seizure onset involving the insular cortex and subsequent ablation, including many patients with prior surgeries involving the frontal, parietal, and temporal lobes. The insula serves as an ideal target for LITT, given the deep location and surrounding anatomic structures. There are limited studies on the efficacy of LITT in adults with lesional or non-lesional insular epilepsy. Retrospective LITT studies as well as comparisons with open surgical resection in the pediatric population have, however, shown good comparative efficacy while also demonstrating minimal, often transient, post-operative complications.

Keywords

surgerylaser interstitial thermal therapylaser ablationLITT
Type
Chapter
Information
Insular Epilepsies , pp. 287 - 298
Publisher: Cambridge University Press
Print publication year: 2022

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References

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