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Chapter 6 - New concepts in ovarian stimulation

Published online by Cambridge University Press:  16 May 2011

David K. Gardner
Affiliation:
University of Melbourne
Botros R. M. B. Rizk
Affiliation:
University of South Alabama
Tommaso Falcone
Affiliation:
Cleveland Clinic Foundation
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Summary

Increased understanding of the intricacies of the follicular development and selection processes has been critical to the development of many of the new developments in ovarian stimulation in clinical practice. This chapter reviews these clinically related physiological aspects of ovarian stimulation, and discusses the resulting new concepts of ovarian stimulation. Recent studies have indicated that anti-Mullerian hormone (AMH) may be a more reliable and robust predictor of ovarian response during ovarian stimulation. The long ovarian stimulation protocol combining GnRH agonist with exogenous gonadotropin administration has been the most popular treatment regime for the past 20 years. The objectives of ovarian stimulation in assisted reproductive technology (ART) are evolving. A further development which promises to further reduce the burden of ovarian stimulation is the introduction of a long-acting follicle stimulating hormone (FSH) preparation which greatly reduces the number of injections required during an in vitro fertilization (IVF) treatment cycle.
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Human Assisted Reproductive Technology
Future Trends in Laboratory and Clinical Practice
, pp. 54 - 72
Publisher: Cambridge University Press
Print publication year: 2011

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