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Chapter 34 - Uterus Transplantation

Clinical Practice

from Section 9 - New Research and Technologies

Published online by Cambridge University Press:  27 March 2021

By
Mats Brännström ,
Jana EJ Pittman  and
Pernilla Dahm-Kähler
Edited by
Jacques Donnez  and
S. Samuel Kim
Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Summary

Uterus transplantation (UTx) has now repeatedly shown that women with absolute uterine factor infertility (AUFI) can achieve both genetic and gestational motherhood [1–3]. Along with enabling the woman to experience pregnancy, UTx eliminates the issues around surrogacy, where legalities greatly vary between countries. In comparison to most other types of transplants, UTx can utilize both deceased donor (DD) and live donor (LD) grafts. It is also currently the only transient transplant to remain in situ for a short period of the lifetime of the recipient, thus greatly reducing the risk of the well-described long-term immunosuppressive side effects, such as nephrotoxicity.

Type
Chapter
Information
Fertility Preservation
Principles and Practice
 , pp. 394 - 403
Publisher: Cambridge University Press
Print publication year: 2021

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References

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