Book contents
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Chapter 28 Molecular and Cellular Integrity of Cultured Follicles
- Chapter 29 In Vitro Growth of Human Oocytes
- Chapter 30 Contributions of Ovarian Stromal Cells to Follicle Culture
- Chapter 31 In Vitro Maturation of Germinal Vesicle Oocytes
- Chapter 32 Survival of Primordial Follicles
- Section 9 New Research and Technologies
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Chapter 29 - In Vitro Growth of Human Oocytes
from Section 8 - In Vitro Follicle Culture
Published online by Cambridge University Press: 27 March 2021
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Chapter 28 Molecular and Cellular Integrity of Cultured Follicles
- Chapter 29 In Vitro Growth of Human Oocytes
- Chapter 30 Contributions of Ovarian Stromal Cells to Follicle Culture
- Chapter 31 In Vitro Maturation of Germinal Vesicle Oocytes
- Chapter 32 Survival of Primordial Follicles
- Section 9 New Research and Technologies
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Summary
Patients with cancer who desire to preserve their future reproductive potential but require immediate gonadotoxic treatments (chemo and/or radiotherapy) are left with few options for fertility preservation. These options include (a) cryopreservation of ovarian tissues as cortical strips; (b) dual cryopreservation of both ovarian cortical tissue and cryopreservation, after in vitro maturation, of immature oocytes extracted from the small antral follicles visible within the ovarian cortex at the time of the harvest; and (c) cryopreservation of one whole ovary [1–9]. At the time of this writing, each of these options is still considered experimental by the American Society of Reproductive Medicine (thus requiring institutional review board approval and patient’s informed consent), although it is expected that soon ovarian tissue cryopreservation will no longer be considered experimental.
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- Information
- Fertility PreservationPrinciples and Practice, pp. 332 - 340Publisher: Cambridge University PressPrint publication year: 2021