Published online by Cambridge University Press: 05 March 2021
The majority of salivary gland lesions are benign. However, the lack of uniform reporting among institutions and the morphologic overlap, diversity, and heterogeneity of salivary gland neoplasms (due to cellularity, patterns, subtypes, and metaplastic changes) sometimes result in inconclusive, nonreproducible, descriptive diagnosis, thereby limiting the value of fine needle aspiration biopsy (FNAB). The Milan system for reporting salivary gland cytopathology (MSRSGC), a six-tiered evidence and risk based international consensus diagnostic classification, was first established in Milan, Italy, during the 2015 annual meeting of the European Cytology Congress. It aimed to standardize the nomenclature, to include ancillary techniques, to provide a risk of malignancy (ROM) for each category, and to guide clinical management in correlation with contrast enhanced CT or MRI findings.
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