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Chapter 10 - Drugs for Airway Management

from Section 1 - Airway Management: Background and Techniques

Published online by Cambridge University Press:  03 October 2020

Tim Cook
Affiliation:
Royal United Hospital, Bath, UK
Michael Seltz Kristensen
Affiliation:
Rigshospitalet, Copenhagen University Hospital, Denmark
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Summary

Correct choice and use of drugs is fundamental to airway management success and safety. This is true for both elective and emergency anaesthesia and at the start and end of anaesthesia. This chapter describes the key elements of drug selection for safe, effective airway management in both the awake and anaesthetised patient. Drugs can importantly facilitate airway management and influence conditions for tracheal intubation or inserting a supraglottic airway. Depression of reflexes and muscle tone can be provided by several hypnotics, but propofol is usually most effective. Neuromuscular blocking agents are not needed for many forms of airway management but can optimise conditions when necessary. The anaesthetist must be familiar with dosing and timing and with quantitative monitoring during reversal. Local anaesthesia may be the only safe choice in managing the difficult airway and sedation can enhance patient tolerance but maintaining adequate spontaneous ventilation is sometimes a challenge.

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Publisher: Cambridge University Press
Print publication year: 2020

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References

Further Reading

Bouvet, L, Stoian, A, Rimmelé, T, et al. (2009). Optimal remifentanil dosage for providing excellent intubating conditions when co-administered with a single standard dose of propofol. Anaesthesia, 64, 719726.CrossRefGoogle ScholarPubMed
Mencke, T, Echternach, M, Kleinschmidt, S, et al. (2003). Laryngeal morbidity and quality of tracheal intubation: a randomized controlled trial. Anesthesiology, 98, 10491056.CrossRefGoogle ScholarPubMed
Wang, H, Gao, X, Wei, W, et al. (2017). The optimum sevoflurane concentration for supraglottic airway device Blockbuster™ insertion with spontaneous breathing in obese patients: a prospective observational study. BMC Anesthesiology, 17, 156Google Scholar

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