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Case 40 - Corticobasal: The Syndrome versus the Pathology

from Part 8 - Attributing Findings to a Known or Suspected Disorder

Published online by Cambridge University Press:  03 November 2020

Keith Josephs ,
Federico Rodriguez-Porcel ,
Rhonna Shatz ,
Daniel Weintraub  and
Alberto Espay
Keith Josephs
Affiliation:
Mayo Clinic Alzheimer’s Disease Research Center
Federico Rodriguez-Porcel
Affiliation:
Medical University of South Carolina
Rhonna Shatz
Affiliation:
University of Cincinnati
Daniel Weintraub
Affiliation:
University of Pennsylvania
Alberto Espay
Affiliation:
University of Cincinnati
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Summary

This 68-year-old right-handed woman experienced a 6-year history of memory impairment. Her family first noticed she had difficulty recalling significant dates and recipes. She became more repetitive and forgetful, particularly for recent events and conversations. Impaired orientation and ability to follow directions prevented her from driving. In the two years prior to her evaluation, she became withdrawn and irritable, and exhibited left hemibody stiffness, leg dragging, and decreased arm swing. When asked about her ability to use tools, she noticed she no longer could use her left hand, attributing this to being right-handed.

Type
Chapter
Information
Common Pitfalls in Cognitive and Behavioral Neurology
A Case-Based Approach
 , pp. 126 - 128
Publisher: Cambridge University Press
Print publication year: 2020

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References

Armstrong, M. J. et al. 2013. Criteria for the diagnosis of corticobasal degeneration. Neurology 80(5) 496–503.Google Scholar
Borroni, B. et al. 2011. CSF Alzheimer’s disease–like pattern in corticobasal syndrome: evidence for a distinct disorder. J Neurol Neurosurg Psychiatry 82(8) 834–838.Google Scholar
Boyd, C. D. et al. 2014. Visuoperception test predicts pathologic diagnosis of Alzheimer disease in corticobasal syndrome. Neurology 83(6) 510–519.Google Scholar
Chahine, L. M. et al. 2014. Corticobasal syndrome: five new things. Neurol Clin Pract 4(4) 304–312.Google Scholar
Hassan, A. and Josephs, K. A. 2016. Alien hand syndrome. Curr Neurol Neurosci Rep 16(8) 73.CrossRefGoogle ScholarPubMed
Hassan, A., Whitwell, J. L. and Josephs, K. A. 2011. The corticobasal syndrome-Alzheimer’s disease conundrum. Expert Rev Neurother 11(11) 1569–1578.CrossRefGoogle ScholarPubMed
Lee, S. E. et al. 2011. Clinicopathological correlations in corticobasal degeneration. Ann Neurol 70(2) 327–340.Google Scholar
Pardini, M. et al. 2019. FDG-PET patterns associated with underlying pathology in corticobasal syndrome. Neurology 92(10) e1121.Google Scholar
Rodriguez-Porcel, F. et al. 2016. Fulminant corticobasal degeneration: agrypnia excitata in corticobasal syndrome. Neurology 86(12) 1164–1166.Google Scholar
Shelley, B. P. et al. 2009. Is the pathology of corticobasal syndrome predictable in life? Mov Disord 24(11) 1593–1599.Google Scholar
Whitwell, J. L. et al. 2010. Imaging correlates of pathology in corticobasal syndrome. Neurology 75(21) 1879–1887.CrossRefGoogle ScholarPubMed

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