Published online by Cambridge University Press: 16 May 2024
Over the past few decades, the role of inflammation in the pathophysiology of depressive disorder and bipolar disorder has been the focus of considerable attention. In this chapter, we provide an update on the association between inflammatory processes and mood disorders, in light of available evidence. The pathophysiological and clinical implications of this association are critically discussed, as well as the interaction between inflammation, metabolic abnormalities, and medical comorbidities, which have important prognostic consequences for patients with mood disorders.
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