Skip to main content Accessibility help
×
Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-22T20:30:18.206Z Has data issue: false hasContentIssue false

Chapter 2 - The Classification of Mood Disorders and the Unipolar/Bipolar Dichotomy

Published online by Cambridge University Press:  16 May 2024

Allan Young
Affiliation:
Institute of Psychiatry, King's College London
Marsal Sanches
Affiliation:
Baylor College of Medicine, Texas
Jair C. Soares
Affiliation:
McGovern Medical School, The University of Texas
Mario Juruena
Affiliation:
King's College London
Get access

Summary

The concept of abnormal mood has been a matter of a millennia-long debate in philosophy and medicine, while the diagnosis and classification of mood disorders remains a complex and controversial issue even in modern psychiatry. A centrepiece of this debate is the conceptualisation of mood and, by extension, mood disorders as a multi-dimensional spectrum with transdiagnostic symptoms (i.e., a continuous diagnostic classification) or as discrete nosological entities (i.e., a categorical diagnostic classification). Theoretical models and arguments based on empirical evidence have been proposed for both the distinct categorisation of abnormal mood states and the affective continuum perspective, which may also encompass psychosis and psychotic disorders. Although the conceptualisation of mood as a spectrum ranging from unipolar depression to unipolar mania may be the most suitable, this approach requires further evidence before it can replace the categorical classifications firmly employed in clinical practice for more than a century.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Gitlin, M, Malhi, GS. The existential crisis of bipolar II disorder. Int J Bipolar Disord [Internet]. 2020;8(1):5. Available from: https://doi.org/10.1186/s40345-019-0175-7CrossRefGoogle ScholarPubMed
Joober, R, Tabbane, K. From the neo-Kraepelinian framework to the new mechanical philosophy of psychiatry: regaining common sense. J Psychiatry Neurosci [Internet]. 2019 Jan 1;44(1):37. Available from: https://pubmed.ncbi.nlm.nih.gov/30565447CrossRefGoogle Scholar
Kendler, KS. The transformation of American psychiatric nosology at the dawn of the twentieth century. Mol Psychiatry [Internet]. 2016;21(2):152–8. Available from: https://doi.org/10.1038/mp.2015.188CrossRefGoogle ScholarPubMed
Shorter, E. The history of nosology and the rise of the Diagnostic and Statistical Manual of Mental Disorders. Dialogues Clin Neurosci [Internet]. 2015 Mar;17(1):5967. Available from: https://pubmed.ncbi.nlm.nih.gov/25987864CrossRefGoogle ScholarPubMed
Nettle, D, Bateson, M. The evolutionary origins of mood and its disorders. Curr Biol [Internet]. 2012;22(17):R712–21. Available from: www.sciencedirect.com/science/article/pii/S0960982212006653CrossRefGoogle ScholarPubMed
Baldessarini, RJ. A plea for integrity of the bipolar disorder concept. Bipolar Disord. 2000;2(1):37.CrossRefGoogle ScholarPubMed
Angst, J. Bipolar disorders in DSM-5: strengths, problems and perspectives. Int J Bipolar Disord [Internet]. 2013;1(1):12. Available from: https://doi.org/10.1186/2194-7511-1-12CrossRefGoogle ScholarPubMed
Pelletier, L, O’Donnell, S, Dykxhoorn, J, McRae, L, Patten, SB. Under-diagnosis of mood disorders in Canada. Epidemiol Psychiatr Sci [Internet]. 2017;26(4):414–23. Available from: www.cambridge.org/core/article/underdiagnosis-of-mood-disorders-in-canada/68581D51E09F9955DABEE8E0450DC0E2CrossRefGoogle ScholarPubMed
Smith, DJ, Ghaemi, N. Is underdiagnosis the main pitfall when diagnosing bipolar disorder? Yes. BMJ [Internet]. 2010 Feb 22;340:c854. Available from: www.bmj.com/content/340/bmj.c854.abstractCrossRefGoogle ScholarPubMed
Zimmerman, M. Is underdiagnosis the main pitfall in diagnosing bipolar disorder? BMJ [Internet]. 2010 Feb 22;340:c855. Available from: www.bmj.com/content/340/bmj.c855.abstractCrossRefGoogle ScholarPubMed
de Leon, J. Paradoxes of US psychopharmacology practice in 2013: undertreatment of severe mental illness and overtreatment of minor psychiatric problems. J Clin Psychopharmacol. 2014;34(5):545–8.CrossRefGoogle ScholarPubMed
Glick, ID. Undiagnosed bipolar disorder: new syndromes and new treatments. Prim Care Companion J Clin Psychiatry [Internet]. 2004;6 (1):2733. Available from: https://pubmed.ncbi.nlm.nih.gov/15486598CrossRefGoogle ScholarPubMed
Singh, T, Rajput, M. Misdiagnosis of bipolar disorder. Psychiatry (Edgmont) [Internet]. 2006 Oct;3(10):5763. Available from: https://pubmed.ncbi.nlm.nih.gov/20877548Google ScholarPubMed
Benazzi, F. Borderline personality–bipolar spectrum relationship. Prog Neuropsychopharmacol Biol Psychiatry [Internet]. 2006;30(1):6874. Available from: www.sciencedirect.com/science/article/pii/S0278584605002058CrossRefGoogle ScholarPubMed
Kuhn, TS. The Structure of Scientific Revolutions. Vol. 111. Chicago: University of Chicago Press, 1970.Google Scholar
Berrios, GE. The History of Mental Symptoms: Descriptive Psychopathology since the Nineteenth Century. Cambridge: Cambridge University Press, 1996.CrossRefGoogle Scholar
Berrios, GE. Melancholia and depression during the 19th century: a conceptual history. Br J Psychiatry [Internet]. 2018/01/02. 1988;153(3):298304. Available from: www.cambridge.org/core/article/melancholia-and-depression-during-the-19th-century-a-conceptual-history/5257E8A5BA6C993A023F32462378CC92CrossRefGoogle ScholarPubMed
Kendler, KS. An historical framework for psychiatric nosology. Psychol Med [Internet]. 2009 Dec;39(12):1935–41. Available from: https://pubmed.ncbi.nlm.nih.gov/19368761CrossRefGoogle ScholarPubMed
Kendler, KS, Parnas, J, eds. Philosophical Issues in Psychiatry. Vol. II: Nosology. Oxford: Oxford University Press, 2013. Available from: https://oxfordmedicine.com/view/10.1093/med/9780199642205.001.0001/med-9780199642205-chapter-015001Google Scholar
Kendell, RE. The Classification of Depressive Illnesses. Vol. 18. Oxford: Oxford University Press, 1968.Google Scholar
Kendler, KS. The transformation of American psychiatric nosology at the dawn of the twentieth century. Mol Psychiatry [Internet]. 2016;21(2):152–8. Available from: https://doi.org/10.1038/mp.2015.188CrossRefGoogle ScholarPubMed
Shorter, E. History of psychiatry. Curr Opin Psychiatry. 2008;21(6):593.CrossRefGoogle ScholarPubMed
Angst, J, Marneros, A. Bipolarity from ancient to modern times: conception, birth and rebirth. J Affect Disord [Internet]. 2001;67(1):319. Available from: www.sciencedirect.com/science/article/pii/S0165032701004293CrossRefGoogle ScholarPubMed
Charney, AW, Mullins, N, Park, YJ, Xu, J. On the diagnostic and neurobiological origins of bipolar disorder. Transl Psychiatry [Internet]. 2020;10(1):118. Available from: https://doi.org/10.1038/s41398-020-0796-8CrossRefGoogle ScholarPubMed
Pies, R. The historical roots of the “bipolar spectrum”: Did Aristotle anticipate Kraepelin’s broad concept of manic-depression? J Affect Disord [Internet]. 2007;100(1):711. Available from: www.sciencedirect.com/science/article/pii/S0165032706004940CrossRefGoogle ScholarPubMed
Chamsi-Pasha, MAR, Chamsi-Pasha, H. Avicenna’s contribution to cardiology. Avicenna J Med [Internet]. 2014 Jan;4(1):912. Available from: https://pubmed.ncbi.nlm.nih.gov/24678465Google ScholarPubMed
Omrani, A, Holtzman, NS, Akiskal, HS, Ghaemi, SN. Ibn Imran’s 10th century treatise on melancholy. J Affect Disord. 2012;141(2–3):116–19.CrossRefGoogle ScholarPubMed
Amar, Z, Lev, E, Serri, Y. On Ibn Juljul and the meaning and importance of the list of medicinal substances not mentioned by Dioscorides. J R Asiat Soc. 2014;24(4):529–55.Google Scholar
Leonti, M, Casu, L. Ethnopharmacology of love. Front Pharmacol [Internet]. 2018;9. Available from: www.frontiersin.org/article/10.3389/fphar.2018.00567CrossRefGoogle ScholarPubMed
Goldney, RD. The utility of the DSM nosology of mood disorders. Can J Psychiatry. 2006;51(14):874–8.CrossRefGoogle ScholarPubMed
Goldstein, JE. Console and Classify: The French Psychiatric Profession in the Nineteenth Century. Chicago: University of Chicago Press, 2001.Google Scholar
Decker, HS. How Kraepelinian was Kraepelin? How Kraepelinian are the neo-Kraepelinians? – from Emil Kraepelin to DSM-III. Hist Psychiatry [Internet]. 2007 Sep 1;18(3):337–60. Available from: https://doi.org/10.1177/0957154X07078976CrossRefGoogle Scholar
Geddes, JR, Andreasen, NC, Goodwin, GM, et al. New Oxford Textbook of Psychiatry. Oxford: Oxford University Press, 2020. Available from: https://oxfordmedicine.com/view/10.1093/med/9780198713005.001.0001/med-9780198713005-chapter-7CrossRefGoogle Scholar
Stanghellini, G, Fuchs, T. One Century of Karl Jaspers’ General Psychopathology. Oxford: Oxford University Press, 2013.Google Scholar
de Leon, J. DSM-5 and the research domain criteria: 100 years after Jaspers’ General Psychopathology. Am J Psychiatry [Internet]. 2014 May 1;171(5):492–4. Available from: https://doi.org/10.1176/appi.ajp.2013.13091218CrossRefGoogle ScholarPubMed
Kendler, KS, Engstrom, EJ. Kahlbaum, Hecker, and Kraepelin and the transition from psychiatric symptom complexes to empirical disease forms. Am J Psychiatry. 2017;174(2):102–9.CrossRefGoogle ScholarPubMed
Kraam, A. On the Origin of the Clinical Standpoint in Psychiatry: by Dr Ewald Hecker in Görlitz. Hist Psychiatry [Internet]. 2004 Sep 1;15(3):345–60. Available from: https://doi.org/10.1177/0957154X04044598CrossRefGoogle Scholar
Schioldann, J, Berrios, G. “The meaning of the symptom in psychiatry. An overview”, by Hans W. Gruhle (1913). Hist Psychiatry. 2015 Jun 1;26:214–32.CrossRefGoogle Scholar
Kendler, KS. The development of Kraepelin’s concept of dementia praecox: a close reading of relevant texts. JAMA Psychiatry [Internet]. 2020 Nov 1;77(11):1181–7. Available from: https://doi.org/10.1001/jamapsychiatry.2020.1266CrossRefGoogle ScholarPubMed
Kendler, KS. The genealogy of the clinical syndrome of mania: signs and symptoms described in psychiatric texts from 1880 to 1900. Psychol Med [Internet]. 2017/10/11. 2018;48(10):1573–91. Available from: www.cambridge.org/core/article/genealogy-of-the-clinical-syndrome-of-mania-signs-and-symptoms-described-in-psychiatric-texts-from-1880-to-1900/91DA305CB1DB842D9F97C9A74C27B8D2CrossRefGoogle ScholarPubMed
Klerman, GL, Barrett, JE. The affective disorders: clinical and epidemiological aspects. In Gershon, S, Shopsin, B, editors. Lithium: Its Role in Psychiatric Research and Treatment [Internet]. Boston, MA: Springer US, 1973; 201–36. Available from: https://doi.org/10.1007/978-1-4684-2022-7_12Google Scholar
Jablensky, A, Hugler, H, von Cranach, M, Kalinov, K. Kraepelin revisited: a reassessment and statistical analysis of dementia praecox and manic-depressive insanity in 1908. Psychol Med [Internet]. 2009/07/09. 1993;23(4):843–58. Available from: www.cambridge.org/core/article/kraepelin-revisited-a-reassessment-and-statistical-analysis-of-dementia-praecox-and-manicdepressive-insanity-in-1908/2AEB1AA7AB6E80EC2BE7B9C382DD8891CrossRefGoogle Scholar
Roth, SM. Unitary or binary nature of classification of depressive illness and its implications for the scope of manic depressive disorder. J Affect Disord [Internet]. 2001;64(1):118. Available from: www.sciencedirect.com/science/article/pii/S0165032700002378CrossRefGoogle ScholarPubMed
Roth, M. Problems in the classification of affective disorders. Acta Psychiatr Scand [Internet]. 1981 Apr 1;63(s290):4251. Available from: https://doi.org/10.1111/j.1600-0447.1981.tb00706.xCrossRefGoogle Scholar
Wallace, ER IV, Gach, J. History of Psychiatry and Medical Psychology: With an Epilogue on Psychiatry and the Mind-Body Relation. New York: Springer, 2008.CrossRefGoogle Scholar
Crow, TJ. The continuum of psychosis and its implication for the structure of the gene. Br J Psychiatry [Internet]. 2018/01/29. 1986;149(4):419–29. Available from: www.cambridge.org/core/article/continuum-of-psychosis-and-its-implication-for-the-structure-of-the-gene/4ECDA141D36A08E246CAA84208C367F0CrossRefGoogle ScholarPubMed
Akiskal, HS. The bipolar spectrum – the shaping of a new paradigm in psychiatry. Curr Psychiatry Rep. 2002;4(1):13.CrossRefGoogle ScholarPubMed
AKISKAL, HS. The prevalent clinical spectrum of bipolar disorders: beyond DSM-IV. J Clin Psychopharmacol [Internet]. 1996;16(2). Available from: https://journals.lww.com/psychopharmacology/Fulltext/1996/04001/The_Prevalent_Clinical_Spectrum_of_Bipolar.2.aspxCrossRefGoogle ScholarPubMed
Perugi, G, Akiskal, HS. The soft bipolar spectrum redefined: focus on the cyclothymic, anxious-sensitive, impulse-dyscontrol, and binge-eating connection in bipolar II and related conditions. Psychiatr Clin North Am [Internet]. 2002;25(4):713–37. Available from: www.sciencedirect.com/science/article/pii/S0193953X02000230CrossRefGoogle ScholarPubMed
Perugi, G, Akiskal, HS, Lattanzi, L, et al. The high prevalence of “Soft” bipolar (II) features in atypical depression. Comp Psychiatry [Internet]. 1998;39(2):6371. Available from: www.sciencedirect.com/science/article/pii/S0010440X98900803CrossRefGoogle ScholarPubMed
Angst, J. Will mania survive DSM-5 and ICD-11? Int J Bipolar Disord [Internet]. 2015;3(1):24. Available from: https://doi.org/10.1186/s40345-015-0041-1CrossRefGoogle ScholarPubMed
Ghaemi, SN. Bipolar spectrum: a review of the concept and a vision for the future. Psychiatry Investig [Internet]. 2013/09/16. 2013 Sep;10(3):218–24. Available from: https://pubmed.ncbi.nlm.nih.gov/24302943CrossRefGoogle Scholar
Ghaemi, SN, Hippocratic psychopharmacology: a non-DSM approach to practice. In Clinical Psychopharmacology Principles and Practice. Oxford: Oxford University Press, 2019. Available from: https://oxfordmedicine.com/view/10.1093/med/9780199995486.001.0001/med-9780199995486-chapter-16Google Scholar
Ghaemi, SN, Selker, HP. Maintenance efficacy designs in psychiatry: randomized discontinuation trials–enriched but not better. J Clin Transl Sci. 2017;1(3):198204.CrossRefGoogle Scholar
Goodwin, FK, Ghaemi, SN. Prospects for a scientific psychiatry. Acta Neuropsychiatr [Internet]. 1997;9(2):4951. Available from: www.cambridge.org/core/article/prospects-for-a-scientific-psychiatry/630867EDFFC8E69C053ACB565E58B2CBCrossRefGoogle ScholarPubMed
Goodwin, FK, Whitham, EA, Ghaemi, SN. Maintenance treatment study designs in bipolar disorder. CNS Drugs. 2011;25(10):819–27.Google ScholarPubMed
Benazzi, F. Mixed depression: a clinical marker of bipolar-II disorder. Prog Neurosychopharmacol BiolPsychiatry. 2005;29(2):267–74.Google ScholarPubMed
Benazzi, F. Mood patterns and classification in bipolar disorder. Curr Opin Psychiatry. 2006;19(1):18.CrossRefGoogle ScholarPubMed
Sperberg-McQueen, CM. Classification and its structures. In Shreibman, S, Siemens, R, Unsworth, J, editors. A Companion to Digital Humanities. Oxford: Blackwell, 2004: chap. 14.Google Scholar
Kendler, KS. Psychiatric nosology, epistemic iteration, and pluralism. In Kendler, KS, Parnas, J, editors. Philosophical Issues in Psychiatry. Vol. IV: Classification of Psychiatric Illness. Oxford: Oxford University Press, 2017; 246.Google Scholar
Helmer, O, Rescher, N. On the epistemology of the inexact sciences. Manage Sci [Internet]. 1959;6(1):2552. Available from: www.jstor.org/stable/2627474CrossRefGoogle Scholar
Blackwell, B. Corporate corruption in the psychopharmaceutical industry (revised). International Network for the History of Neuropsychopharmacology. March; 2017.Google Scholar
Ban, TA. Academic psychiatry and the pharmaceutical industry. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30(3):429–41.CrossRefGoogle ScholarPubMed
Ban, TA. Development of the language of psychiatry. In Ban, TA, et al., editors. International Network for the History of Neuropsychopharmacology. INHN 2013 (INHN Historical Record). 2020: chap. 17.Google Scholar
Farrell, DM. Recent work on the emotions. Analyse Kritik. 1988;10(1):71102.CrossRefGoogle Scholar
Marks, J. A theory of emotion. Philos Stud. 1982;42(2):227–42.CrossRefGoogle Scholar
Bedford, E. Emotions. Proceed Aristotelian Soc. 1956;57:281304.CrossRefGoogle Scholar
Marks, J. A theory of emotion. Philos Stud. 1982;42(2):227–42.CrossRefGoogle Scholar
Buonomano, D. Your Brain Is a Time Machine: The Neuroscience and Physics of Time. New York: WW Norton, 2017.Google Scholar
Aggarwal, R, Ringold, S, Khanna, D, et al. Distinctions between diagnostic and classification criteria? Arthritis Care Res (Hoboken) [Internet]. 2015 Jul;67(7):891–7. Available from: https://pubmed.ncbi.nlm.nih.gov/25776731CrossRefGoogle ScholarPubMed
Belmonte-Serrano, MA. The myth of the distinction between classification and diagnostic criteria. Reumatol Clin. 2015;11(3):188–9.Google ScholarPubMed
Henry, C, Etain, B. New ways to classify bipolar disorders: going from categorical groups to symptom clusters or dimensions. Curr Psychiatry Rep [Internet]. 2010 Dec;12(6):505–11. Available from: https://pubmed.ncbi.nlm.nih.gov/20878275CrossRefGoogle ScholarPubMed
Baran, L. Dynamical systems and a brief introduction to ergodic theory. Self-published paper. 2014;Google Scholar
Uffink, J. Compendium of the foundations of classical statistical physics. In Butterfield, J, Earman, J, editors. Philosophy of Physics. North Holland, 2006; 9231074.Google Scholar
Elliott, KC. Epistemic and methodological iteration in scientific research. Stud Hist Philos Sci Pt A [Internet]. 2012;43(2):376–82. Available from: www.sciencedirect.com/science/article/pii/S0039368112000039Google Scholar
Möller, HJ. Methodological issues in psychiatry: psychiatry as an empirical science. World J Biol Psychiatry [Internet]. 2001 Jan 1;2(1):3847. Available from: https://doi.org/10.3109/15622970109039983CrossRefGoogle ScholarPubMed
Cassano, GB, Dell’Osso, L, Frank, E, et al. The bipolar spectrum: a clinical reality in search of diagnostic criteria and an assessment methodology. J Affect Disord [Internet]. 1999;54(3):319–28. Available from: www.sciencedirect.com/science/article/pii/S016503279800158XCrossRefGoogle Scholar
Gillman, K. Stepped trials: magnifying methodological muddles – the supernatant effect. PsychoTropical Res. 2019.Google Scholar
Silberzahn, R, Uhlmann, EL, Martin, DP, et al. Many analysts, one data set: making transparent how variations in analytic choices affect results. Adv Methods Pract Psychol Sci [Internet]. 2018 Aug 23;1(3):337–56. Available from: https://doi.org/10.1177/2515245917747646Google Scholar
Uhlmann, EL, Ebersole, CR, Chartier, CR, et al. Scientific Utopia III: crowdsourcing science. Perspect Psychol Sci [Internet]. 2019 Jul 1;14(5):711–33. Available from: https://doi.org/10.1177/1745691619850561CrossRefGoogle ScholarPubMed
Peters, S. Dynamics of spatially extended phenomena – visual analytical approach to movements of lightning clusters. Ph.D. thesis, University of South Australia. 2014.Google Scholar
De Leon, J. Is psychiatry scientific? A letter to a 21st century psychiatry resident. Psychiatry Investig [Internet]. 2013/09/16. 2013 Sep;10(3):205–17. Available from: https://pubmed.ncbi.nlm.nih.gov/24302942CrossRefGoogle ScholarPubMed
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Washington, DC: American Psychiatric Association, 2013.Google Scholar
Wille, L, McMahon, FJ. Coherence through incongruence – can genetic markers inform nosology after all? JAMA Psychiatry [Internet]. 2018 Jan 1;75(1):78. Available from: https://doi.org/10.1001/jamapsychiatry.2017.3484CrossRefGoogle Scholar
Angst, J, Azorin, JM, Bowden, CL, et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry. 2011;68(8):791–9.CrossRefGoogle Scholar
Möller, HJ, Jäger, M, Riedel, M, et al. The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: comparison of psychopathological and psychosocial course and outcome and prediction of chronicity. Eur Arch Psychiatry Clin Neurosci [Internet]. 2010;260(5):367–84. Available from: https://doi.org/10.1007/s00406-010-0117-yCrossRefGoogle ScholarPubMed
Mullins, N, Forstner, AJ, O’Connell, KS, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nat Genet [Internet]. 2021;53(6):817–29. Available from: https://doi.org/10.1038/s41588-021-00857-4CrossRefGoogle ScholarPubMed
Witt, SH, Streit, F, Jungkunz, M, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry [Internet]. 2017 Jun 20;7(6):e1155–e1155. Available from: https://pubmed.ncbi.nlm.nih.gov/28632202CrossRefGoogle ScholarPubMed
Léger, M, Wolff, V, Kabuth, B, Albuisson, E, Ligier, F. The mood disorder spectrum vs. schizophrenia decision tree: EDIPHAS research into the childhood and adolescence of 205 patients. BMC Psychiatry [Internet]. 2022 Mar 18;22(1):194. Available from: https://pubmed.ncbi.nlm.nih.gov/35300648CrossRefGoogle ScholarPubMed
Amare, AT, Vaez, A, Hsu, YH, et al. Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. Mol Psychiatry [Internet]. 2020;25(7):1420–9. Available from: https://doi.org/10.1038/s41380-018-0336-6CrossRefGoogle ScholarPubMed
Schulze, TG, Akula, N, Breuer, R, et al. Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder. World J Biol Psychiatry [Internet]. 2012/03/09. 2014 Apr;15(3):200–8. Available from: https://pubmed.ncbi.nlm.nih.gov/22404658CrossRefGoogle ScholarPubMed
Alarcón, RD. Culture, cultural factors and psychiatric diagnosis: review and projections. World Psychiatry [Internet]. 2009 Oct;8(3):131–9. Available from: https://pubmed.ncbi.nlm.nih.gov/19812742CrossRefGoogle ScholarPubMed
Dudek, D, Siwek, M, Zielińska, D, Jaeschke, R, Rybakowski, J. Diagnostic conversions from major depressive disorder into bipolar disorder in an outpatient setting: results of a retrospective chart review. J Affect Disord. 2013;144(1–2):112–5.CrossRefGoogle Scholar
Wendt, FR, Pathak, GA, Tylee, DS, Goswami, A, Polimanti, R. Heterogeneity and polygenicity in psychiatric disorders: a genome-wide perspective. Chronic Stress (Thousand Oaks) [Internet]. 2020 Jan 1;4:2470547020924844. Available from: https://doi.org/10.1177/2470547020924844Google ScholarPubMed
Malhi, GS, Geddes, JR. Carving bipolarity using a lithium sword. Br J Psychiatry [Internet]. 2014;205(5):337–9. Available from: www.cambridge.org/core/article/carving-bipolarity-using-a-lithium-sword/A81A879C5C80B070F3C7641F00EB7EB9CrossRefGoogle ScholarPubMed
Kontos, N, Freudenreich, O, Querques, J. Out-patient institutionalisation. Br J Psychiatry [Internet]. 2014;205(5):339–339. Available from: www.cambridge.org/core/article/outpatient-institutionalisation/F74D3B70CB9771635CB6272426E57942CrossRefGoogle Scholar
Taylor, MA, Abrams, R. Reassessing the bipolar-unipolar dichotomy. J Affect Disord [Internet]. 1980;2(3):195217. Available from: www.sciencedirect.com/science/article/pii/0165032780900051CrossRefGoogle ScholarPubMed
Parker, G, Hall, W, Boyce, P, et al. Depression sub-typing: unitary, binary or arbitrary? Aust N Z J Psychiatry [Internet]. 1991 Mar 1;25(1):6376. Available from: https://doi.org/10.3109/00048679109077720CrossRefGoogle ScholarPubMed
Ghaemi, SN, Ko, JY, Goodwin, FK. “Cade’s disease” and beyond: misdiagnosis, antidepressant use, and a proposed definition for bipolar spectrum disorder. Can J Psychiatry. 2002;47(2):125–34.CrossRefGoogle Scholar
Angst, J. The bipolar spectrum. Br J Psychiatry [Internet]. 2007;190(3):189–91. Available from: www.cambridge.org/core/article/bipolar-spectrum/418765D7EB2BDB1EB16B1EFA407BF724CrossRefGoogle ScholarPubMed
Akiskal, HS, Maser, JD, Zeller, PJ, et al. Switching from “unipolar” to bipolar II: an 11-year prospective study of clinical and temperamental predictors in 559 patients. Arch Gen Psychiatry. 1995;52(2):114–23.CrossRefGoogle Scholar
Akiskal, HS, Walker, P, Puzantian, VR, et al. Bipolar outcome in the course of depressive illness: phenomenologic, familial, and pharmacologic predictors. J Affect Disord. 1983;5(2):115–28.CrossRefGoogle ScholarPubMed
Ghaemi, SN, Stoll, AL, Pope, HG. Lack of insight in bipolar disorder. The acute manic episode. J Nerv Ment Dis. 1995;183(7):464–7.CrossRefGoogle ScholarPubMed
Klerman, GL. The spectrum of mania. Comp Psychiatry. 1981;22(1):1120.CrossRefGoogle ScholarPubMed
Akiskal, HS, Djenderedjian, AH, Rosenthal, RH, Khani, MK. Cyclothymic disorder: validating criteria for inclusion in the bipolar affective group. Am J Psychiatry. 1977;134(11):1227–33.Google ScholarPubMed
Akiskal, HS, Pinto, O. The evolving bipolar spectrum: prototypes I, II, III, and IV. Psychiatr Clin North Am. 1999;22(3):517–34.CrossRefGoogle ScholarPubMed
Smith, DJ, Forty, L, Russell, E, et al. Sub-threshold manic symptoms in recurrent major depressive disorder are a marker for poor outcome. Acta Psychiatr Scand [Internet]. 2009 Apr 1;119(4):325–9. Available from: https://doi.org/10.1111/j.1600-0447.2008.01324.xCrossRefGoogle ScholarPubMed
Liu, X, Jiang, K. Should major depressive disorder with mixed features be classified as a bipolar disorder? Shanghai Arch Psychiatry [Internet]. 2014 Oct;26(5):294–6. Available from: https://pubmed.ncbi.nlm.nih.gov/25477723Google ScholarPubMed
Savitz, J, Drevets, WC. Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide. NeurosciBiobehav Rev [Internet]. 2009;33(5):699771. Available from: www.sciencedirect.com/science/article/pii/S0149763409000062Google ScholarPubMed
Nassir Ghaemi, S. Why antidepressants are not antidepressants: STEP-BD, STAR*D, and the return of neurotic depression. Bipolar Disord [Internet]. 2008 Dec 1;10(8):957–68. Available from: https://doi.org/10.1111/j.1399-5618.2008.00639.xCrossRefGoogle Scholar
Akiskal, HS, Grinspoon, L. Psychiatry Update: The American Psychiatric Association Annual Review. Vol 2. Washington, DC, 1983; 271.Google Scholar
Ghaemi, SN, Dalley, S. The bipolar spectrum: conceptions and misconceptions. Aust N Z J Psychiatry [Internet]. 2014 Mar 7;48(4):314–24. Available from: https://doi.org/10.1177/0004867413504830CrossRefGoogle ScholarPubMed
Akiskal, HS, Pinto, O. The evolving bipolar spectrum: prototypes I, II, III, and IV. Psychiatr Clin North Am. 1999;22(3):517–34.CrossRefGoogle ScholarPubMed
Akiskal, HS, Akiskal, KK, Lancrenon, S, et al. Validating the bipolar spectrum in the French National EPIDEP Study: overview of the phenomenology and relative prevalence of its clinical prototypes. J Affect Disord. 2006;96(3):197205.CrossRefGoogle ScholarPubMed
Angst, J. The etiology and nosology of endogenous depressive psychoses. Foreign Psychiatry. 1973;2:1108.Google Scholar
Angst, J. The emerging epidemiology of hypomania and bipolar II disorder. J Affect Disord. 1998;50(2–3):143–51.CrossRefGoogle ScholarPubMed
Benazzi, F. Depressive mixed states: unipolar and bipolar II. Eur Arch Psychiatry Clin Neurosci. 2000;250(5):249–53.CrossRefGoogle ScholarPubMed
Angst, J, Azorin, JM, Bowden, CL, et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry. 2011;68(8):791–9.CrossRefGoogle Scholar
Benazzi, F. Depressive mixed state: testing different definitions. Psychiatry ClinNeurosci. 2001;55(6):647–52.Google ScholarPubMed
Benazzi, F. Depressive mixed state frequency: age/gender effects. Psychiatry Clin Neurosci. 2002;56(5):537–43.CrossRefGoogle ScholarPubMed
Benazzi, F. Mixed depression: a clinical marker of bipolar-II disorder. Prog Neuropsychopharmacol BiolPsychiatry. 2005;29(2):267–74.Google ScholarPubMed
Benazzi, F, Akiskal, HS. Delineating bipolar II mixed states in the Ravenna–San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes. J Affect Disord. 2001;67(1–3):115–22.CrossRefGoogle Scholar
Benazzi, F. Mixed depression and the dimensional view of mood disorders. Psychopathology. 2007;40(6):431–9.CrossRefGoogle ScholarPubMed
Akiskal, HS. The dark side of bipolarity: detecting bipolar depression in its pleomorphic expressions. J Affect Disord [Internet]. 2005;84(2):107–15. Available from: www.sciencedirect.com/science/article/pii/S0165032704001843CrossRefGoogle ScholarPubMed
Koukopoulos, A, Faedda, G, Proietti, R, et al. Mixed depressive syndrome. L’encephale. 1992;18:1921.Google ScholarPubMed
Ghaemi, SN. On Depression: Drugs, Diagnosis, and Despair in the Modern World. JHU Press, 2013.CrossRefGoogle Scholar
Benazzi, F. Mood patterns and classification in bipolar disorder. CurrOpin Psychiatry [Internet]. 2006;19(1). Available from: https://journals.lww.com/co-psychiatry/Fulltext/2006/01000/Mood_patterns_and_classification_in_bipolar.2.aspxGoogle ScholarPubMed
Akiskal, HS, Bourgeois, ML, Angst, J, et al. Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders. J Affect Disord [Internet]. 2000;59:S530. Available from: www.sciencedirect.com/science/article/pii/S0165032700002032CrossRefGoogle ScholarPubMed
Gama Marques, J, Ouakinin, S. Schizophrenia–schizoaffective–bipolar spectra: an epistemological perspective. CNS Spectrums [Internet]. 2021;26(3):197201. Available from: www.cambridge.org/core/article/schizophreniaschizoaffectivebipolar-spectra-an-epistemological-perspective/BCD44BC80E44989D8F7AAD8F71582E9FCrossRefGoogle ScholarPubMed
Koukopoulos, A, Sani, G, Koukopoulos, AE, et al. Endogenous and exogenous cyclicity and temperament in bipolar disorder: review, new data and hypotheses. J Affect Disord [Internet]. 2006;96(3):165–75. Available from: www.sciencedirect.com/science/article/pii/S0165032706003661CrossRefGoogle ScholarPubMed
Haslam, N. Categorical versus dimensional models of mental disorder: the taxometric evidence. Aust N Z J Psychiatry [Internet]. 2003 Dec 1;37(6):696704. Available from: https://doi.org/10.1080/j.1440-1614.2003.01258.xCrossRefGoogle ScholarPubMed
Grisanzio, KA, Goldstein-Piekarski, AN, Wang, MY, et al. Transdiagnostic symptom clusters and associations with brain, behavior, and daily function in mood, anxiety, and trauma disorders. JAMA Psychiatry [Internet]. 2018 Feb 1;75(2):201–9. Available from: https://pubmed.ncbi.nlm.nih.gov/29197929CrossRefGoogle ScholarPubMed
Akiskal, HS. The dark side of bipolarity: detecting bipolar depression in its pleomorphic expressions. J Affect Disord [Internet]. 2005;84(2):107–15. Available from: www.sciencedirect.com/science/article/pii/S0165032704001843CrossRefGoogle ScholarPubMed
Cassano, GB, Rucci, P, Frank, E, et al. The mood spectrum in unipolar and bipolar disorder: arguments for a unitary approach. Am J Psychiatry [Internet]. 2004;161(7):1264–9. Available from: https://doi.org/10.1176/appi.ajp.161.7.1264CrossRefGoogle ScholarPubMed
Perugi, G, Passino, MCS, Toni, C, Maremmani, I, Angst, J. Is unipolar mania a distinct subtype? Comp Psychiatry [Internet]. 2007;48(3):213–7. Available from: www.sciencedirect.com/science/article/pii/S0010440X07000120CrossRefGoogle Scholar
Angst, J, Grobler, C. Unipolar mania: a necessary diagnostic concept. Eur Arch Psychiatry Clin Neurosci [Internet]. 2015;265(4):273–80. Available from: https://doi.org/10.1007/s00406-015-0577-1CrossRefGoogle Scholar
Merikangas, KR, Cui, L, Heaton, L, et al. Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Mol Psychiatry. 2014;19(2):214–9.Google ScholarPubMed
Baek, JH, Eisner, LR, Nierenberg, AA. Epidemiology and course of unipolar mania: results from the national epidemiologic survey on alcohol and related conditions (NESARC). Depress Anxiety. 2014;31(9):746–55.CrossRefGoogle ScholarPubMed
Angst, J, Rössler, W, Ajdacic‐Gross, V, et al. Differences between unipolar mania and bipolar‐I disorder: evidence from nine epidemiological studies. Bipolar Disord. 2019;21(5):437–48.CrossRefGoogle ScholarPubMed
Luty, J. Bordering on the bipolar: a review of criteria for ICD-11 and DSM-5 persistent mood disorders. BJPsych Advances [Internet]. 2020;26(1):50–7. Available from: www.cambridge.org/core/article/bordering-on-the-bipolar-a-review-of-criteria-for-icd11-and-dsm5-persistent-mood-disorders/D73A8F4F22A635353B17DFF36AB9301BCrossRefGoogle Scholar
Davidson, JRT, Miller, RD, Turnbull, CD, Sullivan, JL. Atypical depression. Arch Gen Psychiatry [Internet]. 1982 May 1;39(5):527–34. Available from: https://doi.org/10.1001/archpsyc.1982.04290050015005CrossRefGoogle ScholarPubMed
Thase, ME. Atypical depression: useful concept, but it’s time to revise the DSM-IV criteria. Neuropsychophar macology [Internet]. 2009;34(13):2633–41. Available from: https://doi.org/10.1038/npp.2009.100Google ScholarPubMed
Sargant, W. The treatment of anxiety states and atypical depression by the MAOI drugs. J Neuropsychiatry. 1962;3(1):96103.Google Scholar
Liebowitz, MR, Quitkin, FM, Stewart, JW, et al. Antidepressant specificity in atypical depression. Arch Gen Psychiatry. 1988;45(2):129–37.CrossRefGoogle ScholarPubMed
Quitkin, FM, Stewart, JW, McGrath, PJ, et al. Phenelzine versus imipramine in the treatment of probable atypical depression: defining syndrome boundaries of selective MAOI responders. Am J Psychiatry. 1988;145(3):306–11.Google ScholarPubMed
Parker, G, Roy, K, Mitchell, P, Wilhelm, K, Malhi, G, Hadzi-Pavlovic, D. Atypical depression: a reappraisal. Am J Psychiatry [Internet]. 2002 Sep 1;159(9):1470–9. Available from: https://doi.org/10.1176/appi.ajp.159.9.1470CrossRefGoogle ScholarPubMed
Sani, G, Vöhringer, PA, Barroilhet, SA, Koukopoulos, AE, Ghaemi, SN. The Koukopoulos Mixed Depression Rating Scale (KMDRS): an International Mood Network (IMN) validation study of a new mixed mood rating scale. J Affect Disord. 2018;232:916.CrossRefGoogle ScholarPubMed
Sato, T, Bottlender, R, Sievers, M, Möller, HJ. Evidence of depressive mixed states. Am J Psychiatry. 2005;162(1):193-a.CrossRefGoogle ScholarPubMed
Koukopoulos, A, Albert, MJ, Sani, G, Koukopoulos, AE, Girardi, P. Mixed depressive states: nosologic and therapeutic issues. Int Rev Psychiatry. 2005;17(1):2137.CrossRefGoogle ScholarPubMed
Benazzi, F, Akiskal, H. Irritable-hostile depression: further validation as a bipolar depressive mixed state. J Affect Disord. 2005;84(2–3):197207.CrossRefGoogle ScholarPubMed
Akiskal, HS, Benazzi, F. Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II? J Affect Disord. 2005;84(2–3):209–17.CrossRefGoogle ScholarPubMed
Benazzi, F. The continuum/spectrum concept of mood disorders: is mixed depression the basic link? Eur Arch Psychiatry Clin Neurosci. 2006;256(8):512–15.CrossRefGoogle ScholarPubMed
Akiskal, HS, Benazzi, F, Perugi, G, Rihmer, Z. Agitated “unipolar” depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J Affect Disord. 2005;85(3):245–58.CrossRefGoogle ScholarPubMed
Akiskal, HS, Benazzi, F. The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum. J Affect Disord. 2006;92(1):4554.CrossRefGoogle Scholar
Angst, J, Gamma, A. Diagnosis and course of affective psychoses: was Kraepelin right? Eur Arch Psychiatry Clin Neurosci [Internet]. 2008;258(2):107. Available from: https://doi.org/10.1007/s00406-008-2013-2CrossRefGoogle ScholarPubMed
Saggese, JM, Lieberman, DZ, Goodwin, FK. The role of recurrence and cyclicity in differentiating mood disorder diagnoses. Primary Psychiatry. 2006;13(11):43–8.Google Scholar
Akiskal, HS, Djenderedjian, AM, Rosenthal, RH, Khani, MK. Cyclothymic disorder: validating criteria for inclusion in the bipolar affective group. Am J Psychiatry. 1977;134(11):1227–33.Google ScholarPubMed
Akiskal, HS, Akiskal, K. Reassessing the prevalence of bipolar disorders: clinical significance and artistic creativity. Psychiatry Psychobiol. 1988;3(S1):29s36s.CrossRefGoogle Scholar
Ghaemi, SN, Ko, JY, Goodwin, FK. The bipolar spectrum and the antidepressant view of the world. J Psychiatr Pract. 2001;7(5):287–97.Google ScholarPubMed
Healy, D. Mania: A Short History of Bipolar Disorder. JHU Press, 2008.CrossRefGoogle Scholar
Akiskal, HS, Akiskal, KK. TEMPS: Temperament Evaluation of Memphis, Pisa, Paris and San Diego. J Affect Disord. 2005;85(1–2):12.CrossRefGoogle ScholarPubMed
Rihmer, Z, Akiskal, KK, Rihmer, A, Akiskal, HS. Current research on affective temperaments. Curr Opin Psychiatry [Internet]. 2010;23(1). Available from: https://journals.lww.com/co-psychiatry/Fulltext/2010/01000/Current_research_on_affective_temperaments.4.aspxCrossRefGoogle ScholarPubMed
Kwapil, TR, DeGeorge, D, Walsh, MA, et al. Affective temperaments: Unique constructs or dimensions of normal personality by another name? J Affect Disord [Internet]. 2013;151(3):882–90. Available from: www.sciencedirect.com/science/article/pii/S0165032713005995CrossRefGoogle ScholarPubMed
Akiskal, HS, Placidi, GF, Maremmani, I, et al. TEMPS-I: delineating the most discriminant traits of the cyclothymic, depressive, hyperthymic and irritable temperaments in a nonpatient population. J Affect Disord. 1998;51(1):719.CrossRefGoogle Scholar
Akiskal, HS, Akiskal, KK, Lancrenon, S, et al. Validating the bipolar spectrum in the French National EPIDEP Study: overview of the phenomenology and relative prevalence of its clinical prototypes. J Affect Disord. 2006;96(3):197205.CrossRefGoogle ScholarPubMed
Scandinavica, AP, Akiskal, HS. Demystifying borderline personality: critique of the concept and unorthodox reflections on its natural kinship with the bipolar spectrum. Acta Psychiatr Scand. 2004;110:401–7.Google Scholar
Akiskal, HS, Akiskal, KK, Haykal, RF, Manning, JS, Connor, PD. TEMPS-A: progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire. J Affect Disord. 2005;85(1–2):316.CrossRefGoogle ScholarPubMed
Paris, J. Borderline or bipolar? Distinguishing borderline personality disorder from bipolar spectrum disorders. Harv Rev Psychiatry. 2004;12(3):140–5.CrossRefGoogle ScholarPubMed
Zimmerman, M. Diagnosing personality disorders: a review of issues and research methods. Arch Gen Psychiatry. 1994;51(3):225–45.CrossRefGoogle ScholarPubMed
Skodol, AE, Shea, MT, Yen, S, White, CN, Gunderson, JG. Personality disorders and mood disorders: perspectives on diagnosis and classification from studies of longitudinal course and familial associations. J Pers Disord [Internet]. 2010 Feb 1;24(1):83108. Available from: https://doi.org/10.1521/pedi.2010.24.1.83CrossRefGoogle ScholarPubMed
Kuiper, S, Curran, G, Malhi, GS. Why is soft bipolar disorder so hard to define? Aus N Z J Psychiatry [Internet]. 2012 Oct 26;46(11):1019–25. Available from: https://doi.org/10.1177/0004867412464063CrossRefGoogle ScholarPubMed
Angst, J, Ajdacic-Gross, V, Rössler, W. Bipolar disorders in ICD-11: current status and strengths. Int J Bipolar Disord [Internet]. 2020 Jan 20;8(1):3. Available from: https://pubmed.ncbi.nlm.nih.gov/31956923CrossRefGoogle ScholarPubMed
Tandon, R. Bipolar and depressive disorders in Diagnostic and Statistical Manual of Mental Disorders-5: clinical implications of revisions from Diagnostic and Statistical Manual of Mental Disorders-IV. Indian J Psychol Med [Internet]. 2015;37(1):14. Available from: https://pubmed.ncbi.nlm.nih.gov/25722503CrossRefGoogle ScholarPubMed
Malhi, GS, Irwin, L, Outhred, T. Counting the days from bipolar II to bipolar true! Acta Psychiatr Scand. 2019;139(3):211–13.CrossRefGoogle ScholarPubMed
di Cerbo, A. convergences and divergences in the ICD-11 vs. DSM-5 classification of mood disorders. Turk Psikiyatri Dergisi. 2021;32(4):293.Google Scholar
Westen, D, Malone, JC, DeFife, JA. An empirically derived approach to the classification and diagnosis of mood disorders. World Psychiatry [Internet]. 2012 Oct;11(3):172–80. Available from: https://pubmed.ncbi.nlm.nih.gov/23024677CrossRefGoogle Scholar
Malhi, GS, Bell, E, Boyce, P, Mulder, R, Porter, RJ. Unifying the diagnosis of mood disorders. Aust N Z J Psychiatry [Internet]. 2020 Jun 1;54(6):561–5. Available from: https://doi.org/10.1177/0004867420926241CrossRefGoogle ScholarPubMed
Insel, TR. Disruptive insights in psychiatry: transforming a clinical discipline. J Clin Invest [Internet]. 2009/04/01. 2009 Apr;119(4):700–5. Available from: https://pubmed.ncbi.nlm.nih.gov/19339761CrossRefGoogle ScholarPubMed
Insel, T, Cuthbert, B, Garvey, MK, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010;167:748–51.CrossRefGoogle Scholar
Cuthbert, B, Insel, T. The data of diagnosis: new approaches to psychiatric classification. Psychiatry. 2010;73(4):311–4.CrossRefGoogle ScholarPubMed
Insel, TR, Cuthbert, BN. Brain disorders? precisely. Science (1979). 2015;348(6234):499500.Google ScholarPubMed
Cuthbert, BN, Insel, TR. Toward new approaches to psychotic disorders: the NIMH Research Domain Criteria project. Schizophr Bull. 2010;36(6):1061–2.CrossRefGoogle ScholarPubMed
Cuthbert, BN, Insel, TR. Toward the future of psychiatric diagnosis: the seven pillars of RDoC. BMC Med. 2013;11(1):18.CrossRefGoogle ScholarPubMed
Cuthbert, BN, Insel, TR. Toward precision medicine in psychiatry: the NIMH research domain criteria project. In Charney, DS, Buxbaum, JD, Sklar, P, Nestler, EJ, editors. Neurobiology of Mental Illness. Oxford: Oxford University Press, 2013:1076–88.Google Scholar
Clark, LA, Cuthbert, B, Lewis-Fernández, R, Narrow, WE, Reed, GM. three approaches to understanding and classifying mental disorder: ICD-11, DSM-5, and the National Institute of Mental Health’s Research Domain Criteria (RDoC). Psychol Sci Public Interest [Internet]. 2017 Nov 1;18(2):72145. Available from: https://doi.org/10.1177/1529100617727266CrossRefGoogle ScholarPubMed
Ahmed, AT, Frye, MA, Rush, AJ, et al. Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders. J Affect Disord [Internet]. 2018 Oct 1;238:17. Available from: https://pubmed.ncbi.nlm.nih.gov/29807322CrossRefGoogle ScholarPubMed
Ban, TA. Thomas A. Ban: RDoC In Historical Perspective: Redefining Mental Illness by Tanya M. Luhrmann. Samuel Gershon’s question. Collated Document Olaf Fjetland. 2017.Google Scholar
Foucher, JR, Gawlik, M, Roth, JN, et al. Wernicke-Kleist-Leonhard phenotypes of endogenous psychoses: a review of their validity. Dialogues Clin Neurosci [Internet]. 2020 Mar;22(1):3749. Available from: https://pubmed.ncbi.nlm.nih.gov/32699504CrossRefGoogle ScholarPubMed
Läge, D, Egli, S, Riedel, M, Strauss, A, Möller, HJ. Combining the categorical and the dimensional perspective in a diagnostic map of psychotic disorders. Eur Arch Psychiatry Clin Neurosci [Internet]. 2011;261(1):310. Available from: https://doi.org/10.1007/s00406-010-0125-yCrossRefGoogle Scholar
Phillips, ML, Kupfer, DJ. Bipolar disorder diagnosis: challenges and future directions. Lancet [Internet]. 2013;381(9878):1663–71. Available from: www.sciencedirect.com/science/article/pii/S0140673613609897CrossRefGoogle ScholarPubMed
Kendler, KS, Zachar, P, Craver, C. What kinds of things are psychiatric disorders? Psychol Med. 2011;41(6):1143–50.CrossRefGoogle ScholarPubMed
Ghaemi, SN. Taking disease seriously: beyond “pragmatic” nosology. In Kendler, KS, Parnas, J, editors, Philosophical Issues in Psychiatry. Vol. II: Nosology. Oxford: Oxford University Press, 2012; 4253.Google Scholar
Möller, H. Development of DSM‐V and ICD‐11: tendencies and potential of new classifications in psychiatry at the current state of knowledge. Psychiatry Clin Neurosci. 2009;63(5):595612.CrossRefGoogle ScholarPubMed
Möller, HJ. Systematic of psychiatric disorders between categorical and dimensional approaches. Eur Arch Psychiatry Clin Neurosci [Internet]. 2008;258(2):4873. Available from: https://doi.org/10.1007/s00406-008-2004-3CrossRefGoogle ScholarPubMed
Möller, HJ, Bandelow, B, Bauer, M, et al. DSM-5 reviewed from different angles: goal attainment, rationality, use of evidence, consequences – part 2: bipolar disorders, schizophrenia spectrum disorders, anxiety disorders, obsessive–compulsive disorders, trauma- and stressor-related disorders, personality disorders, substance-related and addictive disorders, neurocognitive disorders. Eur Arch Psychiatry Clin Neurosci [Internet]. 2015;265(2):87106. Available from: https://doi.org/10.1007/s00406-014-0521-9CrossRefGoogle ScholarPubMed
Fernandez, AV. Reconsidering the affective dimension of depression and mania: towards a phenomenological dissolution of the paradox of mixed states. J Psychopathol. 2014;20(4).Google Scholar
Joober, R, Karama, S. Randomness and nondeterminism: from genes to free will with implications for psychiatry. J Psychiatry Neurosci [Internet]. 2021 Aug 20;46(4):E500–5. Available from: https://pubmed.ncbi.nlm.nih.gov/34415691CrossRefGoogle ScholarPubMed
Soares, JC, Gershon, S. The diagnostic boundaries of bipolar disorder. Bipolar Disord [Internet]. 2000 Mar 1;2(1):12. Available from: https://doi.org/10.1034/j.1399-5618.2000.020101.xCrossRefGoogle ScholarPubMed
Berto, F. There’s Something about Gödel: The Complete Guide to the Incompleteness Theorem. New York: John Wiley & Sons, 2011.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×