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Chapter 28 - Magnetic resonance spectroscopy in intracranial infection

from Section 4 - Infection, inflammation and demyelination

Published online by Cambridge University Press:  05 March 2013

By
Rakesh K. Gupta
Edited by
Jonathan H. Gillard ,
Adam D. Waldman  and
Peter B. Barker
Jonathan H. Gillard
Affiliation:
University of Cambridge
Adam D. Waldman
Affiliation:
Imperial College London
Peter B. Barker
Affiliation:
The Johns Hopkins University School of Medicine
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Summary

Introduction

Infection of the central nervous system (CNS) can be life threatening and results from an encounter of potentially pathogenic microorganism with a susceptible human host.[1] Early diagnosis is necessary for optimal treatment. Routine diagnostic techniques involve culture of various clinical samples and immunological tests, which may be invasive, time consuming, and may delay definitive management. Non-invasive imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) have established themselves in the diagnosis of various CNS diseases; MRI offering greater inherent sensitivity, specificity, and multiplanar capability, while magnetic resonance spectroscopy (MRS) provides additive metabolic information as an adjunct to MRI.

Although MRS has established itself as a non-invasive diagnostic technique for investigating intracranial lesions, its applications in different types of intracranial infection are less well known because there are very few studies available that correlate MRS with MRI in intracranial infections. This chapter reviews studies of MRS in intracranial infections.

Type
Chapter
Information
Clinical MR Neuroimaging
Physiological and Functional Techniques
 , pp. 426 - 455
Publisher: Cambridge University Press
Print publication year: 2009

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