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25 - Transcranial magnetic stimulation and deep brain stimulation

from Section 4 - Specific modalities of treatment

Published online by Cambridge University Press:  05 May 2013

By
Sarah H. Lisanby  and
Moacyr A. Rosa
Edited by
J. John Mann
Edited in association with
Patrick J. McGrath  and
Steven P. Roose
J. John Mann
Affiliation:
Columbia University, New York
Patrick J. McGrath
Affiliation:
Columbia University, New York
Steven P. Roose
Affiliation:
Columbia University, New York
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Summary

This chapter reviews the basic principles of the clinical application of transcranial magnetic stimulation (TMS) for the treatment of major depression. In October 2008, TMS was approved by the Food and Drug Administration (FDA) in the USA for the treatment of adults with medication-resistant unipolar major depressive disorder (MDD) who have failed one adequate pharmacological trial. The World Federation of Societies of Biological Psychiatry's guidelines endorsed the International Society of Transcranial Stimulation (ISTS) guidelines concerning TMS administration. The original uses of TMS were in the study of the motor cortex and motor pathways, where there is a simple and objective way of measuring the effects of the stimulation in the motor system. The cortical area that has been the main target for the treatment of depression with TMS is the dorsolateral prefrontal cortex (DLPFC).

Keywords

premenstrual syndromemenopause transitionmenstrual cyclepremenstrual dysphoric disorderselective serotonin reuptake inhibitorsmajor depressive disorderfemale sex hormonesdepression
Type
Chapter
Information
Clinical Handbook for the Management of Mood Disorders , pp. 325 - 331
Publisher: Cambridge University Press
Print publication year: 2013

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