Clinical Case Studies in Long-Term Care Psychiatry Navigating Common Mental Health Challenges in Geriatric Care
Book contents
- Clinical Case Studies in Long-Term Care Psychiatry
- Clinical Case Studies in Long-Term Care Psychiatry
- Copyright page
- Contents
- Preface
- Section 1 Neurocognitive Disorders
- Case 2 “I Think I Hit My Head”
- Case 3 “It’s like She’s a Different Person”
- Case 4 “I Am Tired All the Time”
- Case 5 “I Am Okay”
- Case 6 “Leave Me Alone”
- Case 7 “I Am Fine”
- Case 8 “Those Children Are Cute”
- Case 9 “Those Terrible Men Have Left”
- Case 10 “I Saw the Heavenly Gates”
- Case 11 “Leave Me Alone”
- Section 2 Mood Disorders
- Case 13 “My Mom Looks Like a Zombie!”
- Case 14 “My Soul Is in England”
- Case 15 “I Feel Terrible”
- Case 16 “I Don’t Care”
- Case 17 “I Feel Very Lonely”
- Case 18 “I Don’t Feel Right”
- Case 19 “I Am Feeling Great”
- Case 20 “I Am Staying Here Illegally”
- Section 3 Psychotic Disorders
- Case 22 “He Just Won’t Get Up”
- Case 23 “My Body Is Being Taken over by a Fungus!”
- Case 24 “This Is Humiliating”
- Case 25 “I Want to Go Home”
- Case 26 “I Am a Worrier”
- Case 27 “Get out of My House”
- Section 4 Anxiety and Related Disorders
- Case 29 “My Vision Has Been Worsening in the Last Two Weeks”
- Case 30 “I Am Not Addicted to Valium”
- Case 31 “Of Course, I Worry about Him”
- Case 32 “Bombs Are Falling! Run, Run!”
- Section 5 Substance Abuse Disorders
- Section 6 Personality Disorders
- Case 35 “I Cannot Wait to Get out of This Miserable Place”
- Section 7 Miscellaneous Neuropsychiatric Disorders Affecting Patients in Long-Term Care
- Case 37 “Everyone Is Just So Good to Me!”
- Case 38 “Why Do They Say I Have Dementia?”
- Case 39 “I Hate That Guy … I Can’t Get Any Sleep!”
- Case 40 “Just One Kiss”
- Case 41 “I Don’t Feel Well”
- Case 42 “I Like Food”
- Case 43 “I Like the Way She Laughs”
- Case 44 “This Is So Hard”
- Index
- References
Case 8 - “Those Children Are Cute”
Cholinesterase Inhibitors and Memantine
Published online by Cambridge University Press: 31 October 2024
Book contents
- Clinical Case Studies in Long-Term Care Psychiatry
- Clinical Case Studies in Long-Term Care Psychiatry
- Copyright page
- Contents
- Preface
- Section 1 Neurocognitive Disorders
- Case 2 “I Think I Hit My Head”
- Case 3 “It’s like She’s a Different Person”
- Case 4 “I Am Tired All the Time”
- Case 5 “I Am Okay”
- Case 6 “Leave Me Alone”
- Case 7 “I Am Fine”
- Case 8 “Those Children Are Cute”
- Case 9 “Those Terrible Men Have Left”
- Case 10 “I Saw the Heavenly Gates”
- Case 11 “Leave Me Alone”
- Section 2 Mood Disorders
- Case 13 “My Mom Looks Like a Zombie!”
- Case 14 “My Soul Is in England”
- Case 15 “I Feel Terrible”
- Case 16 “I Don’t Care”
- Case 17 “I Feel Very Lonely”
- Case 18 “I Don’t Feel Right”
- Case 19 “I Am Feeling Great”
- Case 20 “I Am Staying Here Illegally”
- Section 3 Psychotic Disorders
- Case 22 “He Just Won’t Get Up”
- Case 23 “My Body Is Being Taken over by a Fungus!”
- Case 24 “This Is Humiliating”
- Case 25 “I Want to Go Home”
- Case 26 “I Am a Worrier”
- Case 27 “Get out of My House”
- Section 4 Anxiety and Related Disorders
- Case 29 “My Vision Has Been Worsening in the Last Two Weeks”
- Case 30 “I Am Not Addicted to Valium”
- Case 31 “Of Course, I Worry about Him”
- Case 32 “Bombs Are Falling! Run, Run!”
- Section 5 Substance Abuse Disorders
- Section 6 Personality Disorders
- Case 35 “I Cannot Wait to Get out of This Miserable Place”
- Section 7 Miscellaneous Neuropsychiatric Disorders Affecting Patients in Long-Term Care
- Case 37 “Everyone Is Just So Good to Me!”
- Case 38 “Why Do They Say I Have Dementia?”
- Case 39 “I Hate That Guy … I Can’t Get Any Sleep!”
- Case 40 “Just One Kiss”
- Case 41 “I Don’t Feel Well”
- Case 42 “I Like Food”
- Case 43 “I Like the Way She Laughs”
- Case 44 “This Is So Hard”
- Index
- References
Summary
Alzheimer’s disease is the most common form of major neurocognitive disorder, causing gradual declines in many areas of cognition. Alzheimer’s disease accounts for 60-70% of cases of dementia worldwide. Donepezil is the prototypical cholinesterase inhibitor and was approved for use in 1996. It is FDA approved for the treatment of mild, moderate, or severe Alzheimer’s disease and is considered a symptomatic treatment for Alzheimer’s disease and some other dementias as it does little to alter the course of the disease. The advantages to maintaining patients on cholinesterase inhibitors include continued slowing of the decline in cognition, delaying need for a higher level of care, and potentially delaying the need for medications to address neuropsychiatric symptoms.
- Type
- Chapter
- Information
- Clinical Case Studies in Long-Term Care PsychiatryNavigating Common Mental Health Challenges in Geriatric Care, pp. 33 - 38Publisher: Cambridge University PressPrint publication year: 2024
References
References
Desai, A., & Grossberg, G. (2017). Psychiatric Consultation in Long-Term Care (A Guide for Healthcare Professionals). 2nd ed. (Cambridge University Press.)CrossRefGoogle Scholar
Sharma, K. (2019). Cholinesterase inhibitors as Alzheimer’s therapeutics. Molecular Medicine Reports, 20 (2), 1479–1487. https://doi.org/10.3892/mmr.2019.10374Google ScholarPubMed
Knorz, A. L., & Quante, A. (2022). Alzheimer’s disease: Efficacy of mono- and combination therapy. A systematic review. Journal of Geriatric Psychiatry and Neurology, 35 (4), 475–486. https://doi.org/10.1177/08919887211044746CrossRefGoogle ScholarPubMed
Deardorff, W. J., & Grossberg, G. T. (2015). A fixed-dose combination of memantine extended-release and donepezil in the treatment of moderate-to-severe Alzheimer’s disease. Drug Design, Development and Therapy, 10, 3267–3279. https://doi.org/10.2147/DDDT.S86463CrossRefGoogle Scholar
Reisberg, B. (1988). Functional assessment staging (FAST). Psychopharmacology bulletin, 24 (4), 653–659. PMID: 3249767.Google ScholarPubMed
Further Reading
Boer, D. D., Nguyen, N., Mao, J., Moore, J., & Sorin, E. J. (2021). A comprehensive review of cholinesterase modeling and simulation. Biomolecules, 11 (4). https://doi.org/10.3390/biom11040580Google ScholarPubMed
DeTure, M. A., & Dickson, D. W. (2019). The neuropathological diagnosis of Alzheimer’s disease. Molecular neurodegeneration, 14 (1), 1–18.CrossRefGoogle ScholarPubMed
Guo, J., Wang, Z., Liu, R., Huang, Y., Zhang, N., & Zhang, R. (2020). Memantine, donepezil, or combination therapy: What is the best therapy for Alzheimer’s disease? A network meta‐analysis. Brain and Behavior, 10 (11). https://doi.org/10.1002/brb3.1831CrossRefGoogle ScholarPubMed
Kobayashi, H., Ohnishi, T., Nakagawa, R., & Yoshizawa, K. (2016). The comparative efficacy and safety of cholinesterase inhibitors in patients with mild‐to‐moderate Alzheimer’s disease: A Bayesian network meta‐analysis. International Journal of Geriatric Psychiatry, 31 (8), 892–904.CrossRefGoogle ScholarPubMed
Walczak-Nowicka, Ł. J., & Herbet, M. (2021). Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis. International Journal of Molecular Sciences, 22 (17). https://doi.org/10.3390/ijms22179290CrossRefGoogle ScholarPubMed