Skip to main content Accessibility help
×
Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-23T19:29:24.912Z Has data issue: false hasContentIssue false

Case 12 - “I Am in Hell and I Will Die in Hell”

Treatment-Resistant Depression and Electroconvulsive Therapy

from Section 2 - Mood Disorders

Published online by Cambridge University Press:  31 October 2024

Matthew Gibfried
Affiliation:
Saint Louis University School of Medicine, Missouri
George T. Grossberg
Affiliation:
Saint Louis University School of Medicine, Missouri
Get access

Summary

Major depressive disorder is a serious and life-threatening condition not uncommon to older adults. Only 60-70% of patients respond to an adequate trial of two different antidepressants. Reasonable strategies to address treatment-resistant depression in older adults include adding an antidepressant in another class or adding one or more of many available augmentation agents. When patients have treatment-resistant depression a clinician may need to consider nonpharmacologic therapies for depression such as electroconvulsive therapy or transcranial magnetic stimulation.

Type
Chapter
Information
Clinical Case Studies in Long-Term Care Psychiatry
Navigating Common Mental Health Challenges in Geriatric Care
, pp. 57 - 61
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

References

Dominiak, M., Antosik-Wójcińska, A. Z., Wojnar, M., & Mierzejewski, P. (2021). Electroconvulsive therapy and age: Effectiveness, safety and tolerability in the treatment of major depression among patients under and over 65 years of age. Pharmaceuticals, 14 (6) https://doi.org/10.3390/ph14060582CrossRefGoogle ScholarPubMed
Rosenquist, P. B., Miller, B., & Pillai, A. (2014). The antipsychotic effects of ECT: A review of possible mechanisms. The Journal of ECT, 30 (2), 125131.CrossRefGoogle ScholarPubMed
Rojas, M., Ariza, D., Ortega, Á., Riaño-Garzón, M. E., Chávez-Castillo, M., Pérez, J. L., Cudris-Torres, L., Bautista, M. J., Medina-Ortiz, O., Rojas-Quintero, J., & Bermúdez, V. (2022). Electroconvulsive therapy in psychiatric disorders: A narrative review exploring neuroendocrine–immune therapeutic mechanisms and clinical implications. International Journal of Molecular Sciences, 23 (13). https://doi.org/10.3390/ijms23136918CrossRefGoogle ScholarPubMed
Kelly, M. S., Oliveira-Maia, A. J., Bernstein, M., Stern, A. P., Press, D. Z., Pascual-Leone, A., & Boes, A. D. (2017). Initial response to transcranial magnetic stimulation treatment for depression predicts subsequent response. The Journal of Neuropsychiatry and Clinical Neurosciences, 29 (2), 179. www.ncbi.nlm.nih.gov/pmc/articles/PMC5592731/CrossRefGoogle ScholarPubMed
Mancusi, G., Santovito, M. C., Marrangone, C., Martino, F., Santorelli, M., Miuli, A., Carlo, F. D., Signorelli, M. S., Clerici, M., Pettorruso, M., & Martinotti, G. (2023). Investigating the role of maintenance TMS protocols for major depression: Systematic review and future perspectives for personalized nterventions. Journal of Personalized Medicine, 13 (4). https://doi.org/10.3390/jpm13040697Google Scholar

Further Reading

Bottomley, J. M., LeReun, C., Diamantopoulos, A., Mitchell, S., & Gaynes, B. N. (2020). Vagus nerve stimulation (VNS) therapy in patients with treatment-resistant depression: A systematic review and meta-analysis. Comprehensive Psychiatry, 98, 152156.CrossRefGoogle Scholar
Desai, A., & Grossberg, G. (2018). Psychiatric Consultation in Long-Term Care. A Guide for Healthcare Professionals. 2nd ed. (Cambridge University Press.) pp. 139142.Google Scholar
van Rooij, S. J., Riva-Posse, P., & McDonald, W. M. (2020). The efficacy and safety of neuromodulation treatments in late-life depression. Current Treatment Options in Psychiatry, 7, 337348.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×