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Case 23 - The peace keeper with a left breast mass

Published online by Cambridge University Press:  19 October 2021

By
Diem Nguyen  and
Brenda Jensen
Edited by
Takesha Cooper ,
Gerald Maguire  and
Stephen Stahl
Takesha Cooper
Affiliation:
University of California, Riverside
Gerald Maguire
Affiliation:
University of California, Riverside
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Pretest self-assessment question (answer at the end of the case)

Type
Chapter
Information
Case Studies: Stahl's Essential Psychopharmacology , pp. 269 - 278
Publisher: Cambridge University Press
Print publication year: 2021

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References

Aydin, M, Ilhan, BC, Calisir, S, et al. Continuing clozapine treatment with lithium in schizophrenic patients with neutropenia or leukopenia: brief review of literature with case reports. Ther Adv Psychopharmacol 2016; 6: 33–8. https://doi.org/10.1177/2045125315624063CrossRefGoogle ScholarPubMed
Barreto, JN, Leung, JG, Philbrick, KL, et al. Clozapine therapy throughout myelosuppressive chemotherapy: regulations without standardization. Psychooncology 2015; 24:1581–5. https://doi.org/10.1002/pon.3779CrossRefGoogle ScholarPubMed
Clozapine REMS Program. 2020. Available from https://www.clozapinerems.com/CpmgClozapineUI/home.u (accessed March 26, 2021).Google Scholar
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de Berardis, D, Rapini, G, Olivieri, L, et al. Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine. Ther Adv Drug Saf 2018; 9: 237–56. https://doi.org/10.1177/2042098618756261CrossRefGoogle ScholarPubMed
Ghaznavi, S, Nakic, M, Rao, P, et al. Rechallenging with clozapine following neutropenia: treatment options for refractory schizophrenia. Am J Psychiatry 2008; 165:813–18. https://doi.org/10.1176/appi.ajp.2008.07111823CrossRefGoogle ScholarPubMed
Grainger, BT, Arcasoy, MO, Kenedi, CA. Feasibility of myelosuppressive chemotherapy in psychiatric patients on clozapine: a systematic review of the literature. Eur J Haematol 2019; 103:277–86. https://doi.org/10.1111/ejh.13285CrossRefGoogle ScholarPubMed
Lally, J, Malik, S, Whiskey, E, et al. Clozapine-associated agranulocytosis treatment with granulocyte colony-stimulating factor/granulocyte-macrophage colony-stimulating factor: a systematic review. J Clin Psychopharmacol 2017; 37:441–6. https://doi.org/10.1097/JCP.0000000000000715Google ScholarPubMed
Masuda, T, Misawa, F, Takase, M, et al. Association with hospitalization and all-cause discontinuation among patients with schizophrenia on clozapine vs other oral second-generation antipsychotics: a systematic review and meta-analysis of cohort studies. JAMA Psychiatry 2019; 76:1052–62. https://doi.org/10.1001/jamapsychiatry.2019.1702CrossRefGoogle ScholarPubMed
Meyer, J, Stahl, SM. Clozapine Handbook. New York, NY: Cambridge University Press, 2019.CrossRefGoogle Scholar

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