Book contents
- Case Studies in Dementia
- Case Studies in Dementia
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- Introduction to the diagnosis of dementia
- Case 1 Subjective cognitive complaint
- Case 2 Man with subjective complaints but abnormal CSF
- Case 3 When mild cognitive impairment really is Alzheimer's disease
- Case 4 Lost for words
- Case 5 Woman with right-sided numbness
- Case 6 Don't be fooled by a misleadingly high MMSE score
- Case 7 Hemiparesis followed by dementia
- Case 8 Young man with behavioral symptoms
- Case 9 Woman with visual complaints
- Case 10 Difficulty playing tennis
- Case 11 Progressive aphasia complicated by intracerebral bleeding
- Case 12 Progressive difficulty with naming and object identification
- Case 13 A lady with weakness, fasciculations, and failing memory
- Case 14 Progressive difficulty producing speech
- Case 15 Young man with progressive speech impairment and weakness
- Case 16 Personality disintegration – it runs in the family
- Case 17 Woman with complaints about her left arm
- Case 18 The aged brain: when the pieces don't fit
- Case 19 Hypersexuality in a 69-year-old man
- Case 20 Man with fluctuating confusion
- Case 21 Man with post-operative cognitive impairment
- Case 22 Penicillin for dementia in a young man
- Case 23 Thiamine for dementia in a young woman
- Case 24 Dizziness in someone with HIV
- Case 25 Case of young man smoking pot but with a mother who died of dementia
- Case 26 University educated man with childish behavior
- Case 27 Frontotemporal lobar dementia vs. solvent intoxication: A piece that does not fit the puzzle
- Case 28 Man with difficulty keeping pace
- Case 29 Young woman with abnormal movements but no family history
- Case 30 Elderly lady with right-sided visual hallucinations
- Case 31 Woman with gait impairment and difficulty reading
- Case 32 Man with problems with reading and calculating
- Case 33 Man with gait impairment and urine incontinence
- Case 34 Falling before forgetting
- Case 35 Man who stopped drinking
- Case 36 Woman with dementia and hepatic disease
- Case 37 Young woman with recurrent “stroke” attacks
- Case 38 Young man with slow cognitive decline
- Case 39 Young woman with lateralized motor symptoms
- Index
Case 11 - Progressive aphasia complicated by intracerebral bleeding
Published online by Cambridge University Press: 16 May 2011
Book contents
- Case Studies in Dementia
- Case Studies in Dementia
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- Introduction to the diagnosis of dementia
- Case 1 Subjective cognitive complaint
- Case 2 Man with subjective complaints but abnormal CSF
- Case 3 When mild cognitive impairment really is Alzheimer's disease
- Case 4 Lost for words
- Case 5 Woman with right-sided numbness
- Case 6 Don't be fooled by a misleadingly high MMSE score
- Case 7 Hemiparesis followed by dementia
- Case 8 Young man with behavioral symptoms
- Case 9 Woman with visual complaints
- Case 10 Difficulty playing tennis
- Case 11 Progressive aphasia complicated by intracerebral bleeding
- Case 12 Progressive difficulty with naming and object identification
- Case 13 A lady with weakness, fasciculations, and failing memory
- Case 14 Progressive difficulty producing speech
- Case 15 Young man with progressive speech impairment and weakness
- Case 16 Personality disintegration – it runs in the family
- Case 17 Woman with complaints about her left arm
- Case 18 The aged brain: when the pieces don't fit
- Case 19 Hypersexuality in a 69-year-old man
- Case 20 Man with fluctuating confusion
- Case 21 Man with post-operative cognitive impairment
- Case 22 Penicillin for dementia in a young man
- Case 23 Thiamine for dementia in a young woman
- Case 24 Dizziness in someone with HIV
- Case 25 Case of young man smoking pot but with a mother who died of dementia
- Case 26 University educated man with childish behavior
- Case 27 Frontotemporal lobar dementia vs. solvent intoxication: A piece that does not fit the puzzle
- Case 28 Man with difficulty keeping pace
- Case 29 Young woman with abnormal movements but no family history
- Case 30 Elderly lady with right-sided visual hallucinations
- Case 31 Woman with gait impairment and difficulty reading
- Case 32 Man with problems with reading and calculating
- Case 33 Man with gait impairment and urine incontinence
- Case 34 Falling before forgetting
- Case 35 Man who stopped drinking
- Case 36 Woman with dementia and hepatic disease
- Case 37 Young woman with recurrent “stroke” attacks
- Case 38 Young man with slow cognitive decline
- Case 39 Young woman with lateralized motor symptoms
- Index
Summary
This chapter presents the case of a 63-year-old right-handed woman who was referred for language difficulties. Significant deficits were present in executive and visuospatial functions, as well as language. Language was fluent, characterized by frequent semantic paraphasias, jargonophasia, and occasional word finding difficulties, and decreased understanding. The initial clinical diagnostic impression was that of a progressive but primarily focal cognitive disorder involving predominantly language: primary progressive aphasia (PPA). Autopsy confirmed the presence of a large left frontal hematoma with intraventricular spillage. Diffuse staining for b-amyloid was found in meningeal and cortical arteries, consistent with severe cerebral amyloid angiopathy (CAA). The differential diagnosis for PPA includes variants of fronto-temporal dementia (FTD) and atypical Alzheimer's disease (AD). The clinical profile, with the early onset, strong family history, absence of severe memory complaints on history and amnestic deficits on testing, behavioral changes, and a predominance of executive dysfunction, swayed the diagnosis towards FTD.
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- Information
- Case Studies in DementiaCommon and Uncommon Presentations, pp. 71 - 81Publisher: Cambridge University PressPrint publication year: 2011