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10.7 - Comorbidity and Dual Pathology in Neurodegenerative Disorders

from 10 - Neurodegeneration

Published online by Cambridge University Press:  08 November 2023

By
James B. Rowe  and
Alexander G. Murley
Edited by
Mary-Ellen Lynall ,
Peter B. Jones  and
Stephen M. Stahl
Mary-Ellen Lynall
Affiliation:
University of Cambridge
Peter B. Jones
Affiliation:
University of Cambridge
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Summary

Descriptions of the aetiology of neurodegenerative disorders often focus on their specific molecular and genetic basis of archetypical phenotypes. Clinical trials usually focus on unequivocal and unconfounded cases, through strict inclusion and exclusion criteria. This is understandable in terms of clarity of didactic teaching, and clinical trial efficiency. However, comorbidity is the norm, not the exception.

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Cambridge Textbook of Neuroscience for Psychiatrists , pp. 572 - 578
Publisher: Cambridge University Press
Print publication year: 2023

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