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2b - Highlighting the Value of Dimensional Conceptualizations and Environmental Influences: Commentary on Issues and New Directions in Personality Disorder Genetics

from Part I - Etiology

Published online by Cambridge University Press:  24 February 2020

By
Susan C. South  and
Amber M. Jarnecke
Edited by
Carl W. Lejuez  and
Kim L. Gratz
Carl W. Lejuez
Affiliation:
University of Kansas
Kim L. Gratz
Affiliation:
University of Toledo, Ohio
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Summary

This commentary reflects on Jang and Choi’s (this volume) chapter summarizing the extent work on behavior and molecular genetic studies of personality disorder (PD). The authors argue that more work needs to be done on refining the PD phenotype, as most work in genetics to date has utilized categorical definitions of PD, even though clinical psychology generally and the field of PDs specifically is moving resolutely toward a dimensional conceptualization (as represented in the alternative model of PDs in the DSM-5). They also argue that the real benefit of both quantitative and measured gene approaches to studying PDs might not be the elucidation of more precise heritability estimates or even the identification of specific genes, but the contribution of environmental influences to maladaptive personality traits.

Keywords

dimensionalalternative modelphenotypeendophenotypegene x environment interaction
Type
Chapter
Information
The Cambridge Handbook of Personality Disorders , pp. 44 - 47
Publisher: Cambridge University Press
Print publication year: 2020

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References

American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders (4th ed., Text Revision). Washington, DC: American Psychiatric Association.Google Scholar
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.Google Scholar
Bornovalova, M. A., Hicks, B. M., Iacono, W. G., & McGue, M. (2013). Longitudinal twin study of borderline personality disorder traits and substance use in adolescence: Developmental change, reciprocal effects, and genetic and environmental influences. Personality Disorders, 4(1), 23–32.Google Scholar
Jang, K. L., Livesley, W. J., Vernon, P. A., & Jackson, D. N. (1996). Heritability of personality disorder traits: A twin study. Acta Psychiatrica Scandinavica, 94(6), 438–444.Google Scholar
Kendler, K. S., Aggen, S. H., Czajkowski, N., Røysamb,  E., Tambs,  K., Torgersen,  S., … Reichborn-Kjennerud,  T. (2008). The structure of genetic and environmental risk factors for DSM-IV personality disorders: A multivariate twin study. Archives of General Psychiatry, 65(12), 1438–1446.Google Scholar
Kendler, K. S., Myers, J. M., & Keyes, C. L. (2011). The relationship between the genetic and environmental influences on common externalizing psychopathology and mental wellbeing.  Twin Research and Human Genetics: The Official Journal of the International Society for Twin Studies, 14(6), 516–523.Google Scholar
Kotov, R., Krueger, R. F., Watson, D., Achenbach, T. M., Althoff, R. R., Bagby, R. M., … Zimmerman, M. (2017). The hierarchical taxonomy of psychopathology: A dimensional alternative to traditional nosologies. Journal of Abnormal Psychology, 126, 454–477.Google Scholar
Krueger, R. F., Derringer, J., Markon, K. E., Watson, D., & Skodol, A. E. (2012). Initial construction of a maladaptive personality trait model and inventory for DSM-5. Psychological Medicine, 42, 1879–1890.Google Scholar
Krueger, R. F., & Markon, K. E. (2014). The role of the DSM-5 personality trait model in moving toward a quantitative and empirically based approach to classifying personality and psychopathology. Annual Review of Clinical Psychology, 10(1), 477–501.Google Scholar
Marigorta, U. M., Rodríguez, J. A., Gibson, G., & Navarro, A. (2018). Replicability and prediction: Lessons and challenges from GWAS. Trends in Genetics, 34(7), 504–517.Google Scholar
Miller, J. D., Lynam, D. R., & Campbell, W. K. (2016). Measures of narcissism and their relations to DSM-5 pathological traits: A critical reappraisal. Assessment, 23(1), 3–9.Google Scholar
Reichborn-Kjennerud, T. (2010). The genetic epidemiology of personality disorders. Dialogues in Clinical Neuroscience, 12(1), 103–114.Google Scholar
Smith, G. T., McCarthy, D. M., & Zapolski, T. C. B. (2009). On the value of homogenous constructs for construct validation, theory testing, and the description of psychopathology. Psychological Assessment, 21(3), 272–284.Google Scholar
South, S. C., & DeYoung, N. J. (2013). Behavior genetics of personality disorders: Informing classification and conceptualization in DSM-5. Personality Disorders: Theory, Research, and Treatment, 4(3), 270–283.CrossRefGoogle ScholarPubMed
South, S. C., Krueger, R. F., Knudsen, G. P., Ystrom, E., Czajkowski, N., Aggen, S. H., … Reichborn-Kjennerud, T. (2017). A population based twin study of DSM-5 maladaptive personality domains. Personality Disorders: Theory, Research, and Treatment, 8(4), 366–375.Google Scholar
Thomas, K. M., Yalch, M. M., Krueger, R. F., Wright, A. G. C., Markon, K. E., & Hopwood, C. J. (2013). The convergent structure of DSM-5 personality trait facets and five-factor model trait domains. Assessment, 20(3), 308–311.CrossRefGoogle ScholarPubMed
Widiger, T. A. (2011). Integrating normal and abnormal personality structure: A proposal for DSM-V. Journal of Personality Disorders, 25(3), 338–363.Google Scholar
Widiger, T. A., Bach, B., Chmielewski, M., Clark, L. A., DeYoung, C., Hopwood, C. J., … Thomas, K. M. (2019). Criterion A of the AMPD in HiTOP. Journal of Personality Assessment, 101(4), 345–355.Google Scholar
Widiger, T. A., & Trull, T. J. (2007). Plate tectonics in the classification of personality disorder: Shifting to a dimensional model. American Psychologist, 62(2), 71–83.Google Scholar
Wright, A. G. C. (2016). On the measure and mismeasure of narcissism: A response to ‘Measures of narcissism and their relations to DSM-5 pathological traits: a critical reappraisal’. Assessment, 23(1), 10–17.Google Scholar
Wright, A. G. C., & Simms, L. J. (2014). On the structure of personality disorder traits: Conjoint analyses of the CAT-PD, PID-5, and NEO-PI-3 trait models. Personality Disorders: Theory, Research, and Treatment, 5(1), 43–54.Google Scholar
Wright, Z. E., Pahlen, S., & Krueger, R. F. (2017). Genetic and environmental influences on Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) maladaptive personality traits and their connections with normative personality traits. Journal of Abnormal Psychology, 126(4), 416–428.Google Scholar

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