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1 - Bipolar disorders beyond major depression and euphoric mania

Published online by Cambridge University Press:  10 August 2009

By
Andreas Marneros  and
Frederick K. Goodwin
Edited by
Andreas Marneros  and
Frederick Goodwin
Andreas Marneros
Affiliation:
Martin-Luther University Halle-Wittenberg, Halle, Germany
Frederick K. Goodwin
Affiliation:
George Washington University Medical Center, Washington, DC, USA
Andreas Marneros
Affiliation:
Martin Luther-Universität Halle-Wittenburg, Germany
Frederick Goodwin
Affiliation:
George Washington University, Washington DC
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Summary

Introduction: knowledge from the past, goals for the future

The last five decades have brought essential changes and developments in psychiatry. One of the most important reasons for these developments is certainly the psychopharmacological revolution. The discovery of antipsychotics, antidepressants, mood stabilizers, and other psychotropic substances has had an enormous impact, not only on many fields of research, treatment, social life, and social politics, but also on ideological aspects and attitudes. Concerning psychiatric research, the psychopharmacological revolution has been an important and sustained stimulus not only for the development of neuroscience, genetics, and pharmacology, but also for psychiatric methodology, the development of new diagnostic concepts, and new research on treatment, prognosis, and rehabilitation. One indirect but fundamental development was the rediscovery and rebirth of old diagnostic, nosological, and phenomenological concepts. For example, new pharmacological experiences led to the rediscovery of the relevance of the unipolar–bipolar dichotomy. The concepts examined by Falret (1854), Baillarger (1854), Kleist (1929, 1953), Neele (1949), Leonhard (1957), and others were confirmed in the new psychopharmacological era, including the nosological refinements made by Jules Angst (1966), Carlo Perris (1966), Winokur and Clayton (1967), and others. But soon the enthusiasm for the new psychopharmacology gave way to an increasing awareness of some limitations. Within broadly defined diagnostic groups like schizophrenia, depression, and bipolar disorder, many patients proved to be non-responders or partial responders.

Keywords

agitated depressionbipolar disordersDSM-IVeuphoriaschizoaffective disordersmixed statesrapid cycling
Type
Chapter
Information
Bipolar Disorders
Mixed States, Rapid Cycling and Atypical Forms
 , pp. 1 - 44
Publisher: Cambridge University Press
Print publication year: 2005

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References

Akiskal, H. S. (1981). Subaffective disorders: dysthymic, cyclothymic and bipolar II disorders in the “border-line” realm. Clin. North Am., 4, 25–46.CrossRefGoogle Scholar
Akiskal, H. S. (1992). The mixed states of bipolar I, II, III. Clin. Neuropsychopharm., 15 (suppl. 1a), 632–3.Google Scholar
Akiskal, H. S. (1997). Overview of chronic depressions and their clinical management. In Dysthymia and the Spectrum of Chronic Depressions, ed. Akiskal, H. S. and Cassano, G. B., pp. 1–34. New York: Guilford Press.
Akiskal, H. S. and Mallya, G. (1987). Criteria for the “soft-bipolar spectrum”: treatment implications. Psychopharm. Bull., 23, 68–73.Google Scholar
Akiskal, H. S. and Puzantian, V. R. (1979). Psychotic forms of depression and mania. Psychiatr. Clin. North Am., 2, 419–39.CrossRefGoogle Scholar
Akiskal, H. S. and Pinto, O. (2000). The soft bipolar spectrum: footnotes to Kraepelin on the interface of hypomania, temperament and depression. In Bipolar Disorders. 100 Years after Manic Depressive Insanity, ed. Marneros, A., and Angst, J., pp. 37–62. Dordrecht: Kluwer Academic Publishers.
Akiskal, H. S., Khani, M. K., and Scott-Strauss, A. (1979). Cyclothymic temperament disorders. Psychiatr. Clin. North Am., 2, 527–54.CrossRefGoogle Scholar
Akiskal, H. S., Hantouche, E. G., Bourgeois, M. L., et al. (1998). Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN). J. Affect. Disord, 50, 175–86.CrossRefGoogle Scholar
Alexander, F. G. and Selesnick, S. T. (1966). The History of Psychiatry. New York: Harper and Row.
American Psychiatric Association (1980). Diagnostic and Statistical Manual of Mental Disorders (DSM-111), 3rd edn. Washington, DC: American Psychiatric Association.
American Psychiatric Association (1987). Diagnostic and Statistical Manual of Mental Disorders (DSM-111R), 3rd edn. Washington, DC: American Psychiatric Association.
American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th edn. (DSM-IV). Washington, DC: American Psychiatric Association.
Angst, J. (1966). Zur Ätiologie und Nososlogie endogener depressiver Psychosen. Eine genetische, soziologische und klinische Studie. Berlin: Springer.CrossRef
Angst, J. (1986). The course of affective disorders. Psychopathology, 119 (suppl. 2), 47–52.CrossRefGoogle Scholar
Angst, J. (1988). Recurrent brief depression. A new concept of mild depression. Psychopharmacology, 96 (suppl.), 123.Google Scholar
Angst, J. (1989). Der Verlauf schizoaffektiver Psychosen. In Schizoaffektive Psychosen. Diagnose, Therapie und Prophylaxe, ed. Marneros, A., pp. 47–54. Berlin: Springer.CrossRef
Angst, J. (1992). Recurrent brief psychiatric syndromes of depression, hypomania, neurasthenia, and anxiety from an epidemiological point of view. Neurol. Psychiatry Brain Res., 1, 5–12.Google Scholar
Angst, J. and Marneros, A. (2001). Bipolarity from ancient to modern times: conception, birth and rebirth. J. Affect. Disord., 67, 3–19.CrossRefGoogle Scholar
Angst, J. and Wicki, W. (1992). The Zurich study. XIII. Recurrent brief anxiety. Eur Arch. Psychiatry Clin. Neurosci., 241, 296–300.CrossRefGoogle Scholar
Angst, J., Gamma, A., Sellaro, R., et al. (2002). Toward validation of atypical depression in the community: results of the Zurich cohort study. J. Affect. Disord., 72, 125–38.CrossRefGoogle Scholar
Arnold, L. M., McElroy, S. L., and Keck, P. E. (2000). The role of gender in mixed mania. Compr. Psychiatry, 2, 83–7.CrossRefGoogle Scholar
Baillarger, J. (1854). De la folie à double forme. Ann. Méd-psychol., 6, 369–89.Google Scholar
Bauer, M. S., Whybrow, P. C., Gyulai, L., Gonnel, J., and Yeh, H. S. (1994). Testing definitions of dysphoric mania and hypomania. Prevalence, clinical characteristics and inter-episode stability. J. Affect. Disord., 32, 201–11.CrossRefGoogle Scholar
Benazzi, F. (1999a). Atypical depression in private practice depressed outpatients: a 203-case study. Compr. Psychiatry, 40, 80–3.Google Scholar
Benazzi, F. (1999b). Prevalence of Bipolar II disorder in atypical depression. Eur. Arch. Psychiatry Clin. Neurosci., 249, 62–5.Google Scholar
Berner, P., Gabriel, E., Katschnig, H., et al. (1983). Diagnosekriterien für schizophrene und affective Psychosen. Vienna: Weltverband für Psychiatrie.
Bourgeois, M., Verdoux, H., and Henry-Demotes Mainard, C. (1995). Manies dysphoriques et états mixtes. L'Encephale, 6, 21–32.Google Scholar
Brieger, P. and Marneros, A. (1999). Komorbidität. In Handbuch der unipolaren und bipolaren Erkrankungen, ed. Marneros, A., pp. 446–83. Stuttgart: Thieme.
Calabrese, J. R. and Delucchi, G. A. (1990). Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder. Am. J. Psychiatry, 147, 431–4.CrossRefGoogle Scholar
Calabrese, J. F., Meltzer, H. Y., and Markovitz, P. J. (1991). Clozapine prophylaxis in rapid cycling bipolar disorder. J. Clin. Psychopharmacol, 11, 396–7.CrossRefGoogle Scholar
Calabrese, J. R., Woyshville, M. J., Kimmel, S. E., and Rapport, D. J. (1993). Predictors of valproate response in bipolar rapid cycling. J. Clin. Psychopharmacol, 13, 280–3.CrossRefGoogle Scholar
Calabrese, J. R., Rapport, D. J., Findling, R. L., et al. (2000). Rapid-cycling bipolar disorder. In Bipolar Disorders. 100 Years after Manic Depressive Insanity, ed. Marneros, A. and Angst, J., pp. 89–109. Dordrecht: Kluwer Academic Publishers.
Campbell, J. D. (1953). Manic-Depressive Disease: Clinical and Psychiatric Significance. Philadelphia: JB Lippincott.
Cassano, G. B., Akiskal, H. S., Savino, M., et al. (1992). Proposed subtypes of bipolar II disorder (with hypomanic episodes or cyclothymia) and with hyperthymic temperament. J. Affect. Disord., 26, 127–40.CrossRefGoogle Scholar
Cassidy, F., Forest, K., Murry, E., and Carroll, B. J. (1998a). A factor analysis of signs and symptoms of mania. Arch. Gen. Psychiatry, 55, 27–32.Google Scholar
Cassidy, F., Murry, E., Forest, K., and Carroll, B. (1998b). Signs and symptoms of mania in pure and mixed episodes. J. Affect. Disord., 50, 187–201.Google Scholar
Cohen, S., Khan, A., and Robinson, J. (1988). Significance of mixed features in acute mania. Compr. Psychiatry, 29, 421–6.CrossRefGoogle Scholar
Coryell, W., Endicott, J., and Keller, M. (1992). Rapid cycling affective disorders: demographics, family history and course. Arch. Gen. Psychiatry, 49, 126–31.CrossRefGoogle Scholar
Cowdry, R., Wehr, T., Zis, A., et al. (1983). Thyroid abnormalities associated with rapid-cycling bipolar illness. Arch. Gen. Psychiattry, 40, 414–20.CrossRefGoogle Scholar
Davidson, J. T., Miller, R. D., Turnbull, C. D., et al. (1982). Atypical depression. Arch. Gen. Psychiatry, 39, 527–34.CrossRefGoogle Scholar
Dehio, H. (1984). Ueber Mischzustände im circulären Irresein. Arch. Psychiatrie, XXVI, 598.Google Scholar
Deister, A., Marneros, A., Rohde, A., Staab, B., and Jünemann, H. (1990). Long-term outcome of affective, schizoaffective, and schizophrenic disorders: a comparison. In Affective and Schizoaffective Disorders, ed. Marneros, A. and Tsuang, M. T., pp. 157–67. Berlin: Springer.CrossRef
Dell'Osso, L., Placidi, G. F., Nassi, R., et al. (1991). The manic depressive mixed state: familial, temperamental and psychopathologic characteristics in 108 female inpatients. Eur. Arch. Psychiatry Clin. Neurosci., 240, 234–9.CrossRefGoogle Scholar
Dilsaver, S. C., Chen, Y. W., Swann, A. C., Shoaib, A. M., and Krajewski, K. J. (1994). Suicidality in patients with pure and depressive mania. Am. J. Psychiatry, 151, 1312–15.CrossRefGoogle Scholar
Dilsaver, S. C., Chen, Y. R., Shoaib, A. M., et al. (1999). Phenomenology of mania: evidence for distinct depressed, dysphoric, and euphoric presentations. Am. J. Psychiatry, 156, 426–30.Google Scholar
Drabkin, I. E. (1950). On Acute Disease and on Chronic Diseases/Caelius Aurelianus. Chicago: University of Chicago Press.
Dunner, D. L., and Fieve, R. R. (1974). Clinical factores in lithium-carbonate prophylaxis failure. Arch. Gen. Psychiatry, 30, 229–33.CrossRefGoogle Scholar
Falret, J. P. (1854). De la folie circularie ou forme de maladie mentale caracterisée par l'alternative régulière de la manie et de la mélancolie. Bull. Acad. Natl Med. (Paris), 19, 382–415.Google Scholar
Fischer-Homberger, E. (1968). Das zirkuläre Irresein. Zürich: Juris.
Fujiwara, Y., Honda, T., Tanaka, Y., Aoki, S., and Kuroda, S. (1998). Comparison of early- and late-onset rapid cycling affective disorders: clinical course and response to pharmacotherapy. J. Clin. Psychopharmacol., 8, 282–8.CrossRefGoogle Scholar
Geller, B., and Luby, J. (1997). Child and adolescent bipolar disorder: a review of the past 10 years. J. Am. Acad. Child Adolesc. Psychiatry, 36, 1168–76.CrossRefGoogle Scholar
Goodwin, F. K. and Jamison, K. R. (1990). Manic-Depressive Illness. New York: Oxford University Press.
Griesinger, W. (1845). Die Pathologie und Therapie der psychischen Krankheiten für Ärzte und Studierende. Stuttgart: Krabbe.
Guislain, J. (1838). Abhandlung über die Phrenopathien oder neues System der Seelenstörungen. Stuttgart: L. F. Rieger.
Heinroth, J. C. A. (1818). Lehrbuch der Störungen des Seelenlebens oder der Seelenstörung und ihrer Behandlung–aus rationaler Siocht. Leipzig: Vogel.
Himmelhoch, J. M. (1979). Mixed states, manic-depressive illness, and the nature of mood. Psych. Clin. North Am., 2, 449–59.Google Scholar
Himmelhoch, J. M. (1992). The sources of characterologic presentations of mixed bipolar states. Clin. Neuropharmacol., 15 (suppl. 1), 630A-1 A.CrossRefGoogle Scholar
Himmelhoch, J. M., Coble, P., Kupfer, D. J., and Ingenito, J. (1976a). Agitated psychotic depression associated with severe hypomanic episodes: a rare syndrome. Am. J. Psychiatry, 133, 765–71.Google Scholar
Himmelhoch, J. M., Mulla, D., Neil, J. F., Detre, T. P. and Kupfer, D. J. (1976b). Incidence and significance of mixed affective states in a bipolar population. Arch. Gen. Psychiatry, 33, 1062–6.Google Scholar
Hippokrates, . (1987). Sämtliche Werke. Munich: H. Lüneburg.
Keck, P. E. Jr., McElroy, S. L., Strakowski, S. M., et al. (1998). 12-month outcome of patients with bipolar disorder following hospitalization for a manic or mixed epiode. Am. J. Psychiatry, 155, 646–52.CrossRefGoogle Scholar
Keller, M. B., Lavori, P. W., Coryell, W., et al. (1986). Differential outcome of pure manic, mixed/cycling, and pure depressive episodes in patients with bipolar illness. J.A.M.A., 255, 3138–42.CrossRefGoogle Scholar
Kilzieh, N. and Akiskal, H. S. (1999). Rapid-cycling bipolar disorder. An overview of research and clinical experience. Psychiatr. Clin. North Am., 22, 585–607.Google Scholar
Kleist, K. (1929). Uber zykloide, paranoide und epileptoide Psychosen und über die Frage der Degenerationspsychosen. Schweiz. Arch. Neurol. Psychiatr., 23, 3–37.Google Scholar
Kleist, K. (1953). Die Gliederung der neuropsychischen Erkrankungen. Monatsschr. Psychiatr. Neurologie, 125, 526–54.CrossRefGoogle Scholar
Kotin, J., and Goodwin, F. K. (1972). Depression during mania: clinical observations and theoretical observations. Am. J. Psychiatry, 129, 55–6.CrossRefGoogle Scholar
Koukopoulos, A. and Koukopoulos, A. (1999). Agitated depression as a mixed state and the problem of melancholia. Psychiatr. Clin. North Am., 22, 547–64.CrossRefGoogle Scholar
Koukopoulos, A., Reginaldi, D., Laddomada, P., et al. (1980). Course of the manic depressive cycle and changes caused by treatments. Pharmacopsychiatry, 13, 156–67.CrossRefGoogle Scholar
Koukopoulos, A., Faedda, G., Proietti, R., et al. (1992). A mixed depressive syndrome. Encéphale, 18, 19–21.CrossRefGoogle Scholar
Koukopoulos, A., Reginaldi, D., Minnai, G., et al. (1995). The long term prophylaxis of affective disorders. In Depression and Mania. From Neurology to Treatment, ed. Gessa, G. L., Fratta, W., Pani, L., and Serra, G., pp. 127–47. New York: Raven Press.
Koukopoulos, A., Sani, G., Koukopoulos, A., and Girardi P. (2000). Cyclicity and manic-depressive illness. In Bipolar Disorders. 100 Years after Manic Depressive Insanity, ed. Marneros, A. and Angst, J., pp. 315–334. Dordrecht: Kluwer Academic Publishers.
Kraepelin, E. (1893). Psychiatrie, 4th edn. Leipzig: J. A. Barth.
Kraepelin, E. (1896). Psychiatrie, 5th edn. Leipzig: J. A. Barth.
Kraepelin, E. (1899). Psychiatrie, 6th edn. Leipzig: J. A. Barth.
Kraepelin, E. (1904). Psychiatrie, 7th edn. Leipzig: J. A. Barth.
Kraepelin, E. (1913). Psychiatrie, Ein Lehrbuch für Studierende und Ärzte., vol. 3. Klinische Psychiatrie, edn. Part 2. Leipzig: J. A. Barth.
Kraepelin, E. (1921). Manic-Depressive Insanity and Paranoia. Edinburgh: E & S Livingstone.
Krüger, S., Cooke, R. G., Spegg, C. C., et al. (2003). Relevance of the catatonic syndrome to the mixed manic episode. J. Affect. Disord., 74, 279–85.CrossRefGoogle Scholar
Lange, J. (1928). Die endogenen und reaktiven Gemuetserkrankungen und die manische-depressive Konstitution. In Geisteskrankheiten, ed. Bumke, O., p. 376. Berlin: Springer.
Leonhard, K. (1957). Aufteilung der endogenen Psychosen. Berlin: Akademie Verlag.
Lish, J. D., Gyulai, L., Resnick, S. M., et al. (1993). A family history study of rapid cycling bipolar disorder. Psychiatr. Res., 48, 37–46.CrossRefGoogle Scholar
Maj, M. (1985). Clinical course and outcome of schizoaffective disorders. Acta Psychiatr. Scand., 72, 542–50.CrossRefGoogle Scholar
Maj, M. and Perris, C. (1985). An approach to the diagnosis and classification of schizoaffective disorders for research purposes. Acta Psychiatr. Scand., 72, 405–13.CrossRefGoogle Scholar
Maj, M., Magliano, L., Pirozzi, R., et al, (1994). Validity of rapid cycling as a course specifier for bipolar disorder. Am. J. Psychiatry, 151, 1015–19.Google Scholar
Marneros, A. (1989). Schizoaffektive Psychosen. Diagnose, Therapie und Prophylaxe. Berlin: Springer.CrossRef
Marneros, A. (1999). Handbuch der unipolaren und bipolaren Erkrankungen. Stuttgart: Thieme.
Marneros, A. (2001). Expanding the group of bipolar disorders. J. Affect. Disord., 62, 39–44.CrossRefGoogle Scholar
Marneros, A. and Angst, J. (eds.) (2000). Bipolar Disorders. 100 Years after Manic Depressive Insanity. Dordrecht: Kluwer Academic Publishers.
Marneros, A. and Pillmann, F. (2004). Brief Psychoses. The Acute and Transient Psychotic Disorders. Cambridge: Cambridge University Press.
Marneros, A. and Tsuang, M. T. (1986). Schizoaffective Psychoses. Berlin: Springer.CrossRef
Marneros, A. and Tsuang, M. T. (1990). Affective and Schizoaffective Disorders. Similarities and Differences. Berlin: Springer.CrossRef
Marneros, A., Deister, A., and Rohde, A. (1986). The Cologne study on schizoaffective disorders and schizophrenia suspecta. In Schizoaffective Psychoses, ed. Marneros, A., and Tsuang, M. T., pp. 123–42. Berlin: Springer.CrossRef
Marneros, A., Deister, A., Rohde, A., et al. (1988a). Long-term course of schizoaffective disorders. Part I: Definitions, methods, frequency of episodes and cycles. Eur. Arch. Psychiatr. Neurol. Sci., 237, 264–75.Google Scholar
Marneros, A., Rohde, A., Deister, A., et al. (1988b). Long-term course of schizoaffective disorders. Part II: Length of cycles, episodes and intervals. Eur. Arch. Psychiatr. Neurol. Sci., 237, 276–82.Google Scholar
Marneros, A., Rohde, A., Deister, A., et al. (1988c). Long-term course of schizoaffective disorders. Part III: Onset, type of episodes and syndrome shift, precipitating factors, suicidality, seasonality, inactivity of illness, and outcome. Eur. Arch. Psychiatr. Neurol. Sci., 237, 283–90.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (1989a). Unipolar and bipolar schizoaffective disorders: a comparative study. I. Premorbid and sociodemographic features. Eur. Arch. Psychiatr. Neurol. Sci., 239, 158–63.Google Scholar
Marneros, A., Rohde, A., and Deister, A. (1989b). Unipolar and bipolar schizoaffective disorders: a comparative study. II. Long-term course. Eur. Arch. Psychiatr. Neurol. Sci., 239, 164–70.Google Scholar
Marneros, A., Deister, A., Rohde, A., et al. (1989c). Unipolar and bipolar schizoaffective disorders: a comparative study. III. Long-term outcome. Eur. Arch. Psychiatr. Neurol. Sci., 239, 171–6.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (1990a). The concept of distinct but voluminous bipolar and unipolar diseases. Part I: The bipolar diseases. Eur. Arch. Psychiatr. Clin. Neurol. Sci., 240, 77–84.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (1990b). The concept of distinct but voluminous bipolar and unipolar diseases. Part III: Unipolar and bipolar comparison. Eur. Arch. Psychiatr. Clin. Neurol. Sci., 240, 90–5.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (1990c). The concept of distinct but voluminous bipolar and unipolar diseases. Part III: Unipolar and bipolar comparison. Eur. Arch. Psychiatry Neurosci., 240, 90–5.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (1991a). Affektive, schizoaffektive und schizophrene Psychosen. Eine vergleichende Langzeitistudie. Berlin: Springer.
Marneros, A., Andreasen, N. C., and Tsuang, M. T. (1991b). Negative Versus Positive Schizophrenia. Berlin: Springer.
Marneros, A., Andreasen, N. C., and Tsuang, M. T. (1995). Psychotic Continuum. Berlin: Springer.CrossRef
Marneros, A., Rohde, A., and Deister, A. (1996a). Bipolar mixed illness. Eur. Neuropsychopharmacol., 6 (suppl. 3), 9.Google Scholar
Marneros, A., Rohde, A., Deister, A., and Fischer, J. (1996b). Die gemischt-bipolar Erkrankung. Nervenarzt, 67 (suppl. 1), 67.Google Scholar
Marneros, A., Deister, A., and Rohde, A. (2000). Bipolar schizoaffective disorders. In Bipolar Disorders. 100 Years after Manic Depressive Insanity, ed. Marneros, A. and Angst, J., pp. 111–25. Dordrecht: Kluwer Academic Publishers.
Marneros, A., Röttig, S., Wenzel, A., Blöink, R., and Brieger, P. (2004). Affective and schizoaffective mixed states. Eur. Arch. Psychiatry Clin. Neurosci., 254, 76–81.CrossRefGoogle Scholar
McElroy, S. L., and Weller, B. (1997). Psychopharmacological treatment of bipolar disorder across the lifespan. In American Psychiatric Press Review of Psychiatry, vol. 16, ed. Dickstein, L. J., Riba, M. B., and Oldham, J. M., pp. 12, 31–85. Washington, DC: American Psychiatric Press.
McElroy, S. L., Keck, P. E., Pope, H. G., et al. (1992). Clinical and research implications of the diagnosis of dysphoric or mixed mania or hypomania. Am. J. Psychiatry, 149, 1633–44.CrossRefGoogle Scholar
McElroy, S. L., Strakowski, S. M., Keck, P. E., et al. (1995). Differences and similarities in mixed and pure mania. Compr. Psychiatry, 36, 187–94.CrossRefGoogle Scholar
McElroy, S. L., Strakowski, S. M., West, S. A., et al. (1997). Phenomenology of adolescent and adult mania in hospitalized patients with bipolar disorder. Am. J. Psychiatry, 154, 44–9.CrossRefGoogle Scholar
McElroy, S. L., Freeman, M. P., and Akiskal, H. S. (2000). The mixed bipolar disorder. In Bipolar Disorders. 100 Years after Manic Depressive Insanity, ed. Marneros, A. and Angst, J., pp. 63–88. Dordrecht: Kluwer Academic Publishers.
Neele, E. (1949). Die phantastischen Psychosen nach ihrem Erscheinungs- und Erbbild. Leipzig: J. A. Barth.
Nunn, C. M. H. (1979). Mixed affective states and the natural history of manic-depressive psychosis. Br. J. Psychiatry, 134, 153–60.CrossRefGoogle Scholar
Nurnberger, J. I. Jr., Guroff, J. J., Hamovit, V., Berrettini, W., and Gershon, E. (1988). A family study of rapid cycling bipolar illness. J. Affect. Disord, 15, 87–91.CrossRefGoogle Scholar
Okuma, T. (1993). Effects of carbamazepine and lithium on affective disorders. Neuropsychobiology, 27, 138–45.CrossRefGoogle Scholar
Parker, G., Roy, K., Mitchell, P., et al. (2002). Atypical depression: a reappraisal. Am. J. Psychiatry, 159, 1470–9.CrossRefGoogle Scholar
Perris, C. A. (1966). Study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses. Acta Psychiatr. Scand, 194 (suppl.), 1–89.Google Scholar
Perugi, G., Akiskal, H. S., Micheli, C., et al. (1997). Clinical subtypes of bipolar mixed states: validating a broader European definition in 143 cases. J. Affect. Disord., 43, 169–80.CrossRefGoogle Scholar
Perugi, G., Akiskal, H. S., Lattanzi, L., et al. (1998). The high prevalence of “soft” bipolar (II) features in atypical depression. Compr. Psychiatry, 39, 63–71.CrossRefGoogle Scholar
Pillmann, F., Arndt, T., Ernt, U.et al. (2000). An analysis of Wernicke's original case records; his contribution to the concept of cycloid psychoses. Idist. Psychiatry, 11, 355–69.CrossRefGoogle Scholar
Pillmann, F., Haring, A., Balzuweit, S., et al. (2002). The concordance of ICD-10 acute and transient psychosis and DSM-IV brief psychotic disorder. Psychol. Med., 68, 525–33.CrossRefGoogle Scholar
Post, R. M., Rubinow, D. R., Uhde, T. W., et al. (1989). Dysphoric mania, clinical and biological correlation. Arch. Gen. Psychiatry, 46, 353–8.CrossRefGoogle Scholar
Prien, R. F., Himmelhoch, J. M., and Kupfer, D. J. (1988). Treatment of mixed mania. J. Affect. Disord., 15, 9–15.CrossRefGoogle Scholar
Quitkin, F. M., Rifkin, A., and Klein, D. F. (1978). Imipramine response in deluded depressive patients. Am. J. Psychiatry, 135, 806–11.CrossRefGoogle Scholar
Quitkin, F. M., Stewart, J. W., McGrath, P. J., et al. (1993). Columbia atypical depression. A subgroup of depressives with better response to MAOI than to tricyclic antidepressants or placebo. Br. J. Psychiatry, 21, 30–4.CrossRefGoogle Scholar
Richarz, F. (1858). Ueber Wesen und Behandlung der Melancholie mit Aufregung (Melancholia agitans). Allg. Ztschr. Psychiatr, 15, 28–65.Google Scholar
Secunda, S. K., Swann, A., Katz, A. M., et al. (1987). Diagnosis and treatment of mixed mania. Am. J. Psychiatry, 144, 96–8.CrossRefGoogle Scholar
Strakowski, S. M., McElroy, S. L., Keck, P. E. Jr., and West, S. A. (1996). Suicidality among patients with mixed and manic bipolar disorder. Am. J. Psychiatry, 153, 674–6.CrossRefGoogle Scholar
Swann, A. C., Secunda, S. K., Katz, M. M., et al. (1995). Specificity of mixed affective states: clinical comparison of dysphoric mania and agitated depression. J. Clin. Psychiatry, 56 (suppl. 3), 6–10.Google Scholar
Swann, A. C., Bowden, C. L., Morris, D., et al. (1997). Depression during mania. Arch. Gen. Psychiatry, 54, 37–42.CrossRef
Tay, L. K. and Dunner, D. L. (1992). A report on three patients with “rapid cycling” unipolar depression. Compr. Psychiatry, 33, 253–5.CrossRefGoogle Scholar
Tohen, M., Waternaux, C. M., and Tsuang, M. T. (1990). Outcome in Mania: a 4-year prospective follow-up of 75 patients utilizing survival analysis. Arch. Gen. Psychiatry, 47, 106–11.CrossRefGoogle Scholar
Tondo, L., Baldessarini, R. J., Hennen, J., and Floris, G. (1998). Lithium maintenance treatment of depression and mania in bipolar I and bipolar II disorders. Am. J. Psychiatry, 155, 638–45.CrossRefGoogle Scholar
van Kappadokien, A. (1847). Ursachen und Symptome der chronischen Krankheiten. Ermerins Fz. Apud kemink et filium.
Wehr, T. A. and Goodwin, F. K. (1979). Rapid cycling in manic-depressives induced by tricyclic antidepressants. Arch. Gen. Psychiatry, 36, 555–9.CrossRefGoogle Scholar
West, E. D. and Dally, P. J. (1959). Effects of iproniazid on depressed syndromes. Br. Med. J., 1, 1491–7.CrossRefGoogle Scholar
Weygandt, W. (1899). Über die Mischzustände des manisch-depressiven Irreseins. Munich: J. F. Lehmann.
Winokur, G., and Clayton, P. J. (1967). Family history studies: I. Two types of affective disorders separated according to genetic and clinical factors. In Recent Advances in Biological Psychiatry, vol. 10, ed. Wortis, J., pp. 35–50. New York: Plenum.CrossRef
Winokur, G., Clayton, P. J., and Reich, T. (1969). Manic Depressive Illness. St. Louis: CV Mosby.
World Health Organization (WHO) (1991). Tenth Revision of the International Classification of Diseases. Clinical Descriptions and Diagnostic Guidelines. Geneva: WHO.
World Health Organization (WHO) (1993). The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. Geneva: WHO.
Wu, L. H. and Dunner, D. L. (1993). Suicide attempts in rapid cycling bipolar disorder patients. J. Affect. Disord., 29, 57–61.CrossRefGoogle Scholar

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