Published online by Cambridge University Press: 10 August 2009
Introduction
Karl Kleist, the main creator of the concept of “cycloid psychoses,” wrote in 1928 that many of the cases allocated by Kraepelin into the group of “mixed states” would better be described as “cycloid psychoses.” In Kleist's opinion, cycloid psychoses are bipolar disorders, but do not belong to the category of manic-depressive insanity (Kleist, 1928, 1953). Cycloid psychoses are the essential component of what the World Health Organization (WHO, 1992) defined as “acute and transient psychotic disorder (ATPD)” (ICD-10 F23). We investigated the ATPD by carrying out the Halle Study on Brief and Acute Psychotic Disorder (HASBAP), which is a longitudinal comparative study (Marneros et al., 2000, 2002; Pillmann et al., 2001; 2002a, b; Marneros and Pillmann, 2004). The HASBAP compares patients with acute and transient psychotic disorders with patients diagnosed as having schizophrenia or bipolar schizoaffective disorder, as well as with a mentally healthy control group. In a further step, we now combine the findings of HASBAP with the findings of the Halle Bipolarity Longitudinal Study (HABILOS), already presented in Chapter 1. In this chapter, we longitudinally compare patients diagnosed as having ATPD from the HASBAP with patients diagnosed as having affective or schizoaffective mixed states belonging to the HABILOS group.
Definitions of acute and transient psychotic disorders
As ATPD (ICD-10 F23), the WHO defines psychotic states having an acute or abrupt onset, usually a good prognosis, and typical symptoms. They may or may not be associated with acute stress (Table 9.1).
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