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Chapter 13 - Precursor Lymphoblastic Leukemia/Lymphoma

from Section IV - Precursor Hematopoietic Neoplasms and Related Neoplasms

Published online by Cambridge University Press:  25 November 2023

By
Virginia Knez ,
Billie Carstens  and
Xiayuan Liang
Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Precursor lymphoid neoplasms comprise lymphoblastic leukemias (ALLs) and lymphoblastic lymphomas (LBLs), of either B- or T-cell origin. As a general rule, ALLs and LBLs are considered biologically equivalent. The distinction between ALLs and LBLs is arbitrary. Bone marrow or peripheral blood blasts ≥ 25% are defined as ALL. Neoplasms with predominant extramedullary involvement, bone marrow, or peripheral blood blasts < 25% are classified as LBL.

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Chapter
Information
Atlas of Pediatric Hematopathology , pp. 127 - 139
Publisher: Cambridge University Press
Print publication year: 2023

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