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Chapter 10 - Hodgkin Lymphoma

from Section III - Mature Lymphoid Neoplasm

Published online by Cambridge University Press:  25 November 2023

By
Xiayuan Liang
Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Hodgkin lymphomas (HLs) encompass two morphologically, immunophenotypically, and clinically distinct subtypes of B-lineage lymphoma – classical Hodgkin lymphoma (cHL) and nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) [1–5]. HLs usually affect lymph nodes. These lymphomas are composed of a small number of large dysplastic mononuclear and multinucleated neoplastic cells (Hodgkin, Reed-Sternberg [RS], and lymphocytic and histiocytic [L&H] cells) set in the background of benign inflammatory elements with or without abundant band-like and/or more diffuse collagen fibrosis [1].

Type
Chapter
Information
Atlas of Pediatric Hematopathology , pp. 90 - 97
Publisher: Cambridge University Press
Print publication year: 2023

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References

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