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Chapter 14 - Acute Treatment of Subarachnoid Haemorrhage

from Part IV - Acute Treatment of Haemorrhagic Stroke

Published online by Cambridge University Press:  15 December 2020

Jeffrey L. Saver
Affiliation:
David Geffen School of Medicine, University of Ca
Graeme J. Hankey
Affiliation:
University of Western Australia, Perth
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Summary

Aneurysmal SAH is a severe disease, and the post-haemorrhage period fraught with potential complications that must be recognized and treated early for favourable outcome. While diagnosis of SAH is often straightforward from clinical history and initial CT, some patients will require cerebrospinal fluid evaluation. The aneurysm must be secured urgently to reduce rerupture and clinical worsening. Endovascular coiling is preferable when feasible, but surgical clipping is sometimes needed based on patient or aneurysmal characteristics, or presence of intraparenchymal haemorrhage requiring evacuation. Treatment of symptomatic hydrocephalus with CSF diversion is also crucial. Patients with aneurysmal SAH should be managed by a team of nurses and physicians with neurocritical care, neuroendovascular, and neurosurgical expertise, preferably in a dedicated neurosciences intensive care unit. Early complications include aneurysmal rebleeding, hydrocephalus, and neurogenic cardiopulmonary injury. In the subacute phase, delayed cerebral ischaemia and hyponatremia are more commonly seen. With optimal multidisciplinary management, many patients can return to their previous level of function only weeks after the aneurysm rupture. Still, most treatments in SAH are based on insufficient evidence, and more collaborative research from the bench to the bedside is necessary to continue improving patient outcomes.

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Stroke Prevention and Treatment
An Evidence-based Approach
, pp. 260 - 288
Publisher: Cambridge University Press
Print publication year: 2020

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References

Akhigbe, T, Zolnourian, A, Bulters, D. (2017). Cholesterol-reducing agents for treatment of aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis of randomized controlled trials. World Neurosurg, 101, 476–85.Google Scholar
Alcalá-Cerra, G, Á, Paternina-Caicedo, Díaz-Becerra, C, Moscote-Salazar, LR, Gutiérrez-Paternina, JJ, Niño-Hernández, LM; en representación del Grupo de Investigación en Ciencias de la Salud y Neurociencias (CISNEURO). (2016). External lumbar cerebrospinal fluid drainage in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis of controlled trials. Neurologia, 31(7), 431–44.Google ScholarPubMed
Badjatia, N, Fernandez, L, Schmidt, JM, Lee, K, Claassen, J, Connolly, ES, Mayer, SA. (2010). Impact of induced normothermia on outcome after subarachnoid hemorrhage: a case-control study. Neurosurgery, 66(4), 696700.Google Scholar
Baharoglu, MI, Germans, MR, Rinkel, GJ, Algra, A, Vermeulen, M, van Gijn, J, et al. (2013). Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 8. CD001245.Google Scholar
Bodily, KD, Cloft, HJ, Lanzino, G, Fiorella, DJ, White, PM, Kallmes, DF. (2011). Stent-assisted coiling in acutely ruptured intracranial aneurysms: a qualitative, systematic review of the literature. AJNR Am J Neuroradiol, 32(7), 1232–6.Google Scholar
Boulouis, G, Labeyrie, MA, Raymond, J, Rodriguez-Régent, C, Lukaszewicz, AC, Bresson, D, et al. (2017). Treatment of cerebral vasospasm following aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis. Eur Radiol, 27(8), 3333–42.CrossRefGoogle ScholarPubMed
Bruder, N, Rabinstein, A. (2011). Cardiovascular and pulmonary complications of aneurysmal subarachnoid hemorrhage. Neurocrit Care, 15(2), 257–69.Google Scholar
Cagnazzo, F, di Carlo DT, Cappucci M, Lefevre PH, Costalat V, Perrini P. (2018). Acutely ruptured intracranial aneurysms treated with flow-diverter stents: a systematic review and meta-analysis. AJNR Am J Neuroradiol, 39(9), 1669–75.Google Scholar
Cagnazzo, F, Gambacciani, C, Morganti, R, Perrini, P. (2017). Aneurysm rebleeding after placement of external ventricular drainage: a systematic review and meta-analysis. Acta Neurochir (Wien), 159(4), 695704.CrossRefGoogle ScholarPubMed
Chang, MM, Raval, RN, Southerland, JJ, Adewumi, DA, Bahjri, KA, Samuel, RK, et al. (2016). Beta blockade and clinical outcomes in aneurysmal subarachnoid hemorrhage. Open Neurol J, 30(10), 155–63.Google Scholar
Chen, S, Luo, J, Reis, C, Manaenko, A, Zhang, J. (2017). Hydrocephalus after subarachnoid hemorrhage: pathophysiology, diagnosis, and treatment. Biomed Res Int, 2017, 8584753.Google ScholarPubMed
Cho, WS, Kim JE Park SQ, Ko JK, Kim DW, Park JC, et al. (2018). Korean Clinical Practice Guidelines for aneurysmal subarachnoid hemorrhage. J Korean Neurosurg Soc, 61(2), 127–66.Google Scholar
Choi, W, Kwon, SC, Lee, WJ, Weon, YC, Choi, B, Lee, H, et al. (2017). Feasibility and safety of mild therapeutic hypothermia in poor-grade subarachnoid hemorrhage: prospective pilot study. J Korean Med Sci, 32(8), 1337–44.Google Scholar
Collen, JF, Jackson, JL, Shorr, AF, Moores, LK. (2008). Prevention of venous thromboembolism in neurosurgery: a metaanalysis. Chest, 134(2), 237–49.Google Scholar
Connolly, ES Jr, Rabinstein, AA, Carhuapoma JR Derdeyn CP, Dion J, Higashida RT, et al. (2012). Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke, 43(6), 1711–37.CrossRefGoogle ScholarPubMed
Dewan, MC, Mocco, J. (2015). Current practice regarding seizure prophylaxis in aneurysmal subarachnoid hemorrhage across academic centers. J Neurointerv Surg, 7(2), 146–9.Google Scholar
Dhakal, LP, Hodge, DO, Nagal, J, Mayes, M, Richie, A, Ng, LK, et al. (2015). Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (SAH) headache and meningismus. Neurocrit Care, 22(3), 414–21.Google Scholar
Diringer, MN, Bleck, TP, Claude Hemphill, J 3rd, Menon D, Shutter L, Vespa P, et al.; Neurocritical Care Society. (2011). Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society’s Multidisciplinary Consensus Conference. Neurocrit Care, 15, 211–40.Google Scholar
Doczi, T, Bende, J, Huszka, E, Kiss, J. (1981). Syndrome of inappropriate secretion of antidiuretic hormone after subarachnoid hemorrhage. Neurosurgery, 9(4), 394–7.CrossRefGoogle ScholarPubMed
Dorai, Z, Hynan, LS, Kopitnik, TA, Samson, D. (2003). Factors related to hydrocephalus after aneurysmal subarachnoid hemorrhage. Neurosurgery, 52(4), 763–9; discussion 769771.CrossRefGoogle ScholarPubMed
Dorhout Mees, SM, Rinkel, GJ, Feigin, VL, Algra, A, van den Bergh, WM, Vermeulen, M, et al. (2007a). Calcium antagonists for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 3. CD000277.Google Scholar
Dorhout Mees, SM, van den Bergh, WM, Algra, A, Rinkel, GJ. (2007b). Antiplatelet therapy for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 4. CD006184.Google Scholar
Dupont, S, Rabinstein, AA. (2013). Extent of acute hydrocephalus after subarachnoid hemorrhage as a risk factor for poor functional outcome. Neurol Res, 35(2), 107110.Google Scholar
Dupont, SA, Wijdicks, EF, Manno, EM, Rabinstein, AA. (2008). Thunderclap headache and normal computed tomographic results: value of cerebrospinal fluid analysis. Mayo Clin Proc, 83(12), 1326–31.Google Scholar
Feigin, VF, Rinkel, GJE, Algra, A, Vermeulen, M, van Gijn, J. (1998). Calcium antagonists in patients with aneurysmal subarachnoid hemorrhage: a systematic review. Neurology, 50, 876–83.Google Scholar
Festic, E, Rabinstein, AA, Freeman, WD, Mauricio, EA, Robinson, MT, Mandrekar, J,et al. (2013). Blood transfusion is an important predictor of hospital mortality among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care, 18(2), 209–15.Google Scholar
Fiorella, D, Arthur, AS, Chiacchierini, R, Emery, E, Molyneux, A, Pierot, L. (2017). How safe and effective are existing treatments for wide-necked bifurcation aneurysms? Literature-based objective performance criteria for safety and effectiveness. Neurointerv Surg, 9(12), 11971201.Google Scholar
Gathier, CS, van den Bergh, WM, van der Jagt, M, Verweij, BH, Dankbaar, JW, Müller, MC, et al.; HIMALAIA Study Group. (2018). Induced hypertension for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a randomized clinical trial. Stroke, 49(1), 7683.CrossRefGoogle ScholarPubMed
Ghodsi, SM, Mohebbi, N, Naderi, S, Anbarloie, M, Aoude, A, Habibi Pasdar, SS. (2015). Comparative efficacy of meloxicam and placebo in vasospasm of patients with subarachnoid hemorrhage. Iran J Pharm Res, 14(1), 125–30.Google Scholar
Gomis, P, Graftieaux, JP, Sercombe, R, Hettler, D, Scherpereel, B, Rousseaux, P. (2010). Randomized, double-blind, placebo-controlled, pilot trial of high-dose methylprednisolone in aneurysmal subarachnoid hemorrhage. J Neurosurg, 112(3), 681–8.Google Scholar
Haley, EC, Kassell, NF, Torner, JC. (1992). The International Cooperative Study on the Timing of Aneurysm Surgery. The North American experience. Stroke, 23(2), 205–14.Google Scholar
Hasan, D, Wijdicks, EF, Vermeulen, M. (1990). Hyponatremia is associated with cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage. Ann Neurol, 27(1), 106–08.CrossRefGoogle ScholarPubMed
Hayashi, K, Hirao, T, Sakai, N, Nagata, I; JR-NET2 Study Group. (2014). Current status of endovascular treatment for vasospasm following subarachnoid hemorrhage: analysis of JR-NET2. Neurol Med Chir (Tokyo), 54(2), 107–12.Google Scholar
Hijdra, A, Vermeulen, M, van Gijn, J, van Crevel, H. (1987). Rerupture of intracranial aneurysms: a clinicoanatomic study. J Neurosurg, 67(1), 2933.Google Scholar
Hillman, J, Fridriksson, S, Nilsson, O, Yu, Z, Saveland, H, Jakobsson, KE. (2002). Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study. J Neurosurg, 97(4), 771–8.Google Scholar
Human, T, Diringer, MN, Allen, M, Zipfel, GJ, Chicoine, M, Dacey, R, et al. (2018). Randomized trial of brief versus extended seizure prophylaxis after aneurysmal subarachnoid hemorrhage. Neurocrit Care, 28, 169–74.CrossRefGoogle ScholarPubMed
Ibrahim, GM, Morgan, BR, Macdonald, RL. (2014). Patient phenotypes associated with outcomes after aneurysmal subarachnoid hemorrhage: a principal component analysis. Stroke, 45(3):, 670–6.Google Scholar
Inzitari, D, Poggesi, A. (2005). Calcium channel blockers and stroke. Aging Clin Exp Res, 17(4 Suppl), 1630.Google Scholar
Kassell, NF, Torner, JC, Haley, EC, Adams, HP. (1990). The International Cooperative Study on the Timing of Aneurysm Surgery. Part 2: surgical results. J Neurosurg, 73(1), 3747.Google Scholar
Kirkpatrick, PJ, Turner, CL, Smith, C, Hutchinson, PJ, Murray, GD; Collaborators, STASH. (2014). Simvastatin in aneurysmal subarachnoid haemorrhage (STASH): a multicentre randomised phase 3 trial. Lancet Neurol, 13(7), 666–75.Google Scholar
Kissoon, NR., Mandrekar, JN, Fugate, JE, Lanzino, G, Wijdicks, EF, Rabinstein, AA. (2015). Positive fluid balance is associated with poor outcomes in subarachnoid hemorrhage. J Stroke and Cerebrovasc Dis, 24(10), 2245–51. Epub 8/19/2015.Google Scholar
Klopfenstein, JD, Kim, LJ, Feiz-Erfan, I, Hott, JS, Goslar, P, Zabramski, JM, et al. (2004). Comparison of rapid and gradual weaning from external ventricular drainage in patients with aneurysmal subarachnoid hemorrhage: a prospective randomized trial. J Neurosurg, 100(2), 225–9.Google Scholar
Kramer, AH, Gurka, MJ, Nathan, B, Dumont, AS, Kassell, NF, Bleck, TP. (2008). Complications associated with anemia and blood transfusion in patients with aneurysmal subarachnoid hemorrhage. Crit Care Med, 36(7), 2070–5.CrossRefGoogle ScholarPubMed
Kramer, CL, Pegoli, M, Mandrekar, J, Lanzino, G, Rabinstein, AA. (2017). Refining the association of fever with functional outcome in aneurysmal subarachnoid hemorrhage. Neurocrit Care, 26(1), 41–7. doi:10.1007/s12028–016–0281–7.Google Scholar
Kshettry, VR, Rosenbaum, BP, Seicean, A, Kelly, ML, Schiltz, NK, Weil, RJ. (2014). Incidence and risk factors associated with in-hospital venous thromboembolism after aneurysmal subarachnoid hemorrhage. J Clin Neurosci., 21(2), 282–6.Google Scholar
Le Roux, PD. (2011). Anemia and transfusion after subarachnoid hemorrhage. Neurocrit Care, 15(2), 342–53.Google Scholar
Lennihan, L, Mayer, SA, Fink, ME, Beckford, A, Paik, MC, Zhang, H, et al. (2000). Effect of hypervolemic therapy on cerebral blood flow after subarachnoid hemorrhage: a randomized controlled trial. Stroke, 31(2), 383–91.CrossRefGoogle Scholar
Levine, J, Kofke, A, Cen, L, Chen, Z, Faerber, J, Elliott, JP, et al. (2010). Red blood cell transfusion is associated with infection and extracerebral complications after subarachnoid hemorrhage. Neurosurgery, 66(2), 312–18; discussion 318.Google Scholar
Lindgren, A, Vergouwen, MD, van der Schaaf, I, Algra, A, Wermer, M, Clarke, MJ, Rinkel, GJ. (2018). Endovascular coiling versus neurosurgical clipping for people with aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 8. CD003085. doi:10.1002/14651858.CD003085.pub3.Google ScholarPubMed
Mack, WJ, Ducruet, AF, Hickman, ZL, Kalyvas, JT, Cleveland, JR, Mocco, J, et al. (2008). Doppler ultrasonography screening of poor-grade subarachnoid hemorrhage patients increases the diagnosis of deep venous thrombosis. Neurol Res, 30(9), 889–92.Google Scholar
Madden, LK, Hill, M, May, TL, Human, T, Guanci, MM, Jacobi, J, et al. (2017).The implementation of targeted temperature management: an evidence-based guideline from the Neurocritical Care Society. Neurocrit Care, 27(3), 468–87. doi:10.1007/s12028–017–0469–5.Google Scholar
Malik, AN, Gross, BA, Rosalind Lai, PM, Moses, ZB, Du, R. (2015). Neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. World Neurosurg, 83(6), 880–5CrossRefGoogle ScholarPubMed
Martini, RP, Deem, S, Brown, M, Souter, MJ, Yanez, ND, Daniel, S, et al. (2012). The association between fluid balance and outcomes after subarachnoid hemorrhage. NeurocritCare, 17(2), 191–8.Google Scholar
Matsuda, M, Watanabe, K, Saito, A, Matsumura, K, Ichikawa, M. (2007). Circumstances, activities, and events precipitating aneurysmal subarachnoid hemorrhage. J Stroke Cerebrovasc Dis, 16(1), 25–9.CrossRefGoogle ScholarPubMed
Matsuda, N, Naraoka, M, Ohkuma, H, Shimamura, N, Ito, K, Asano, K, et al. (2016). Effect of cilostazol on cerebral vasospasm and outcome in patients with aneurysmal subarachnoid hemorrhage: a randomized, double-blind, placebo-controlled trial. Cerebrovasc Dis, 42(1–2), 97105.Google Scholar
McDougall, CG, Spetzler, RF, Zabramski, JM, Partovi, S, Hills, NK, Nakaji, P, et al. (2012). The Barrow Ruptured Aneurysm Trial. J Neurosurg, 116(1), 135–44.Google Scholar
Molyneux, AJ, Birks, J, Clarke, A, Sneade, M, Kerr, RSC. (2015). The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). Lancet, 385(9969), 691–7.Google Scholar
Molyneux, A, Kerr, R, Stratton, I, Sandercock, P, Clarke, M, Shrimpton, J, Holman, R; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. (2002). International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet, 360, 1267–74.Google Scholar
Naidech, AM, Kreiter, KT., Janjua, N, Ostapkovich, N, Parra, A, Commichau, C, et al. (2005). Phenytoin exposure is associated with functional and cognitive disability after subarachnoid hemorrhage. Stroke, 36(3), 583–7.Google Scholar
Naidech, AM, Shaibani, A, Garg, RK, Duran, IM, Liebling, SM, Bassin, SL, et al. (2010). Prospective, randomized trial of higher goal hemoglobin after subarachnoid hemorrhage. Neurocritl Care, 13(3), 313–20.Google Scholar
Neil-Dwyer, G, Walter, P, Cruickshank, JM. (1985). Beta-blockade benefits patients following a subarachnoid haemorrhage. Eur J Clin Pharmacol, 28 Suppl., 2529.Google Scholar
Neil-Dwyer, G, Walter, P, Cruickshank, JM, Doshi, B, O’Gorman, P. (1978). Effect of propranolol and phentolamine on myocardial necrosis after subarachnoid haemorrhage. Br Med J, 2(6143), 990–2.Google Scholar
Nieuwkamp, DJ, Setz, LE, Algra, A, Linn, FH, de Rooij, NK, Rinkel, GJ. (2009). Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol, 8(7), 635–42.Google Scholar
Nyquist, P, Bautista, C, Jichici, D, Burns, J, Chhangani, S, DeFilippis, M, et al. (2016). Prophylaxis of venous thrombosis in neurocritical care patients: an evidence-based guideline: a statement for healthcare professionals from the Neurocritical Care Society. Neurocrit Care, 24(1), 4760.Google Scholar
O’Connor, KL, Westover, MB, Phillips, MT, Iftimia, NA, Buckley, DA, Ogilvy, CS, et al. (2014). High risk for seizures following subarachnoid hemorrhage regardless of referral bias. Neurocrit Care, 21, 476–82.Google Scholar
O’Kelly, CJ, Kulkarni, AV, Austin, PC, Urbach, D, Wallace, MC. (2009). Shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage: incidence, predictors, and revision rates. Clinical article. J Neurosurg, 111(5), 1029–35.Google Scholar
Tsurutani, Ohkuma H. H, Suzuki S. (2001). Incidence and significance of early aneurysmal rebleeding before neurosurgical or neurological management. Stroke, 32(5), 1176–80.Google Scholar
Ohman, J, Heiskanen, O. (1989). Timing of operation for ruptured supratentorial aneurysms: a prospective randomized study. J Neurosurg, 70(1), 5560.Google Scholar
Oliveira-Filho, J, Ezzeddine, MA, Segal, AZ, Buonanno, FS, Chang, Y, Ogilvy, CS, et al. (2001). Fever in subarachnoid hemorrhage: relationship to vasospasm and outcome. Neurology, 56(10), 12991304.Google Scholar
Olson, DM, Zomorodi, M, Britz, GW, Zomorodi, AR, Amato, A, Graffagnino, C. (2013). Continuous cerebral spinal fluid drainage associated with complications in patients admitted with subarachnoid hemorrhage. J Neurosurg, 119(4), 974–80.Google Scholar
Panczykowski, D, Pease, M, Zhao, Y, Weiner, G, Ares, W, Crago, E, et al. (2016). Prophylactic antiepileptics and seizure incidence following subarachnoid hemorrhage: a propensity score-matched analysis. Stroke, 47, 1754–60.CrossRefGoogle ScholarPubMed
Panni, P, Fugate, JE, Rabinstein, AA, Lanzino, G. (2017). Lumbar drainage and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a systematic review. J Neurosurg Sci, 61(6), 665–72.Google Scholar
Pegoli, M, Mandrekar, J, Rabinstein, AA, Lanzino, G. (2015). Predictors of excellent functional outcome in aneurysmal subarachnoid hemorrhage. J Neurosurg, 122(2), 414–18.Google Scholar
Perry, JJ, Alyahya, B, Sivilotti, ML, Bullard, MJ, Emond, M, Sutherland, J, et al. (2015). Differentiation between traumatic tap and aneurysmal subarachnoid hemorrhage: prospective cohort study. BMJ, 350, h568.Google Scholar
Perry, JJ, Stiell, IG, Sivilotti, ML, Bullard, MJ, Symington, C, Worster, A, et al. (2011). Sensitivity of computed tomography performed within six hours of onset of headache for diagnosis of subarachnoid haemorrhage: prospective cohort study. BMJ, 343, d4277.Google Scholar
Perry, JJ, Stiell, IG, Sivilotti, ML, Bullard, MJ, Hohl, CM, Sutherland, J, et al. (2013). Clinical decision rules to rule out subarachnoid hemorrhage for acute headache. JAMA, 310(12), 1248–55.Google Scholar
Rabinstein, AA, Bruder, N. (2011). Management of hyponatremia and volume contraction. Neurocrit Care, 15(2), 354–60.Google Scholar
Rabinstein, AA, Sandhu, K. (2007). Non-infectious fever in the neurological intensive care unit: incidence, causes and predictors. J Neurol Neurosurg Psychiatry, 78(11), 1278–80.Google Scholar
Rawal, S, Alcaide-Leon, P, Macdonald, RL, Rinkel, GJ, Victor, JC, Krings, T, et al. (2017). Meta-analysis of timing of endovascular aneurysm treatment in subarachnoid haemorrhage: inconsistent results of early treatment within 1 day. J Neurol Neurosurg Psychiatry, 88(3), 241–8.Google Scholar
Ray, WZ, Strom, RG, Blackburn, SL, Ashley, WW, Sicard, GA, Rich, KM. (2009). Incidence of deep venous thrombosis after subarachnoid hemorrhage. J Neurosurg, 110(5), 1010–14.Google Scholar
Raya, AK, Diringer, MN. (2014). Treatment of subarachnoid hemorrhage. Crit Care Clin, 30(4), 719–33.CrossRefGoogle ScholarPubMed
Reddy, D, Fallah, A, Petropoulos, JA, Farrokhyar, F, Macdonald, RL, Jichici, D. (2014). Prophylactic magnesium sulfate for aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Neurocrit Care, 21(2), 356–64.CrossRefGoogle ScholarPubMed
Rinkel, GJ, Feigin, VL, Algra, A, van Gijn, J. (2004). Circulatory volume expansion therapy for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 4. CD000483.Google Scholar
Saber, H, Desai, A, Palla, M, Mohamed, W, Seraji-Bozorgzad, N, Ibrahim, M (2018). Efficacy of cilostazol in prevention of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a meta-analysis. J Stroke Cerebrovasc Dis, 27(11), 2979–85.Google Scholar
Senbokuya, N, Kinouchi, H, Kanemaru, K, Ohashi, Y, Fukamachi, A, Yagi, S, et al. (2013). Effects of cilostazol on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a multicenter prospective, randomized, open-label blinded end point trial. J Neurosurg, 118(1), 121–30.CrossRefGoogle ScholarPubMed
Smith, MJ, Le Roux, PD, Elliott, JP, Winn, HR. (2004). Blood transfusion and increased risk for vasospasm and poor outcome after subarachnoid hemorrhage. J Eurosurg, 101(1), 17.Google Scholar
Stein, M., Brokmeier, L., Herrmann, J., Scharbrodt, W, Schreiber, V, Bender, M, et al. (2015). Mean hemoglobin concentration after acute subarachnoid hemorrhage and the relation to outcome, mortality, vasospasm, and brain infarction. J Clin Neurosci, 22(3), 530–4.Google Scholar
Suarez, JI, Martin, RH, Calvillo, E, Bershad, EM, Venkatasubba Rao, CP. (2015). Effect of human albumin on TCD vasospasm, DCI, and cerebral infarction in subarachnoid hemorrhage: the ALISAH study. Acta Neurochir. Suppl, 120, 287–90.Google Scholar
Suarez, JI, Martin, RH, Calvillo, E, Dillon, C, Bershad, EM, Macdonald, RL, et al. (2012). The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke, 43(3), 683–90.Google Scholar
Suzuki, S, Sayama, T, Nakamura, T, Nishimura, H, Ohta, M, Inoue, T, et al. (2011). Cilostazol improves outcome after subarachnoid hemorrhage: a preliminary report. Cerebrovasc Dis, 32(1), 8993.Google Scholar
Tam, AK, Ilodigwe, D, Mocco, J, Mayer, S, Kassell, N, Ruefenacht, D, et al. (2010). Impact of systemic inflammatory response syndrome on vasospasm, cerebral infarction, and outcome after subarachnoid hemorrhage: exploratory analysis of CONSCIOUS-1 database. Neurocrit Care, 13(2), 182–9.Google Scholar
Tartara, A, Galimberti, CA, Manni, R, Parietti, L, Zucca, C, Baasch, H, et al. (1991). Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients. Br J Clin Pharmacol, 32(3), 335–40.Google Scholar
Togashi, K, Joffe, AM, Sekhar, L, Kim, L, Lam, A, Yanez, D, et al. (2015). Randomized pilot trial of intensive management of blood pressure or volume expansion in subarachnoid hemorrhage (IMPROVES). Neurosurgery, 76(2), 125–34; discussion 134–125; quiz 135.Google Scholar
Torner, JC, Nibbelink, DW, Burmeister, LF. (1981). Statistical comparison of end results of a randomised treatment study. In Sahs, AL, Nibbelink, DW, Torner, JC, eds., Aneurysmal Subarachnoid Haemorrhage. Report of the Cooperative Study. Baltimore: Urban & Schwarzenberg, pp. 249–75.Google Scholar
Tso, MK, Ibrahim, GM, Macdonald, RL. (2016). Predictors of shunt-dependent hydrocephalus following aneurysmal subarachnoid hemorrhage. World Neurosurg, 86, 226–32.Google Scholar
Tung, P, Kopelnik, A, Banki, N, Ong, K, Ko, N, Lawton, MT, et al. (2004). Predictors of neurocardiogenic injury after subarachnoid hemorrhage. Stroke, 35(2), 548–51.Google Scholar
van der Bilt, IA, Hasan, D, Vandertop, WP, Wilde, AA, Algra, A, Visser, FC, et al. (2009). Impact of cardiac complications on outcome after aneurysmal subarachnoid hemorrhage: a meta-analysis. Neurology, 72(7), 635–42.Google Scholar
van Donkelaar, CE, Bakker, NA, Veeger, NJ, Uyttenboogaart, M, Metzemaekers, JD, Luijckx, GJ, et al. (2015). Predictive factors for rebleeding after aneurysmal subarachnoid hemorrhage: rebleeding aneurysmal subarachnoid hemorrhage study. Stroke, 46(8), 2100–06. Epub 6/13/2015.Google Scholar
Varelas, PN, Abdelhak, T, Wellwood, J, Shah, I, Hacein-Bey, L, Schultz, L, et al. (2010). Nicardipine infusion for blood pressure control in patients with subarachnoid hemorrhage. Neurocrit Care, 13(2), 190–8.Google Scholar
Venkatraman, A, Khawaja, AM, Gupta, S, Hardas, S, Deveikis, JP, Harrigan, MR, Kumar, G. (2018). Intra-arterial vasodilators for vasospasm following aneurysmal subarachnoid hemorrhage: a meta-analysis. J Neurointerv Surg, 10(4), 380–7.Google Scholar
Vergouwen, MD, Algra, A, Rinkel, GJ. (2012). Endothelin receptor antagonists for aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis update. Stroke, 43(10), 2671–6.Google Scholar
Verma, RK, Kottke, R, Andereggen, L, Weisstanner, C, Zubler, C, Gralla, J, et al. (2013). Detecting subarachnoid hemorrhage: comparison of combined FLAIR/SWI versus CT. Eur J Radiol, 82 1539–45.Google Scholar
Wartenberg, KE, Schmidt, JM, Claassen, J, Temes, RE, Frontera, JA, Ostapkovich, N, et al. (2006). Impact of medical complications on outcome after subarachnoid hemorrhage. Crit Care Med, 34(3), 617–23; quiz 624.CrossRefGoogle ScholarPubMed
Whitfield, PC, Kirkpatrick, PJ. (2001). Timing of surgery for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 2. CD001697.Google Scholar
Wijdicks, EF, Vermeulen, M, ten Haaf, JA, Hijdra, A, Bakker, Wh, van Gijn, J. (1985). Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm. Ann Neurol, 18(2): 211–16.Google Scholar
Yamada, S, Ishikawa, M, Yamamoto, K, Ino, T, Kimura, T, Kobayashi, S. (2015). Aneurysm location and clipping versus coiling for development of secondary normal-pressure hydrocephalus after aneurysmal subarachnoid hemorrhage: Japanese Stroke DataBank. J Neurosurg, 123(6), 1555–61.Google Scholar
Yoneda, H, Shirao, S, Nakagawara, J, Ogasawara, K, Tominaga, T, Suzuki, M. (2014). A prospective, multicenter, randomized study of the efficacy of eicosapentaenoic acid for cerebral vasospasm: the EVAS study. World Neurosurg, 81(2), 309–15.Google Scholar
Zhang, S, Wang, L, Liu, M, Wu, B. (2010). Tirilazad for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev, 2. CD006778.Google Scholar
Zwienenberg-Lee, M, Hartman, J, Rudisill, N, Madden, LK, Smith, K, Eskridge, J, et al. (2008). Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke, 39(6): 1759–65.Google Scholar

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