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5 - Olfactory Neurogenesis: A Window on Brain Development

from Section I - Neurology, Neurophysiology and Neuropsychology: Olfactory Clues to Brain Development and Disorder

Published online by Cambridge University Press:  17 August 2009

By
Françios Féron ,
Richard McCurdy ,
John McGrath  and
Alan Mackay-Sim
Edited by
Warrick J. Brewer ,
David Castle  and
Christos Pantelis
Foreword by
Peter Doherty
Warrick J. Brewer
Affiliation:
Mental Health Research Institute of Victoria, Melbourne
David Castle
Affiliation:
University of Melbourne
Christos Pantelis
Affiliation:
University of Melbourne
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Summary

Introduction

It is understandable that members of the public are surprised to learn that a biopsy taken from inside the nose may be able to provide clues into neurological and psychiatric disorders. Those with the knowledge of the development of Freudian psychoanalysis may have a particular shudder of recognition at any project that links psychiatry with surgical procedures on the nose. Wilhelm Fliess (1858–1928) was a Berlin-based Ear, Nose and Throat specialist (oto-rhino-laryngologist), who was preoccupied with the influence of biological rhythms on health and disease. He also developed a bizarre theory linking the erectile tissue in the nose with sexuality. Sigmund Freud, the father of psychoanalysis, corresponded with Fliess over many years. They shared a belief that surgery on the nose could interrupt ‘reflex nasal neuroses’, and thus be an effective treatment for various neurotic disorders thought to be connected to sexuality. The details of this theory do not warrant further scrutiny apart from one incidence that became pivotal in the development of psychoanalysis. Freud had sent one of his most celebrated patients (Emma Eckstein) to Fliess for the nasal surgery as a treatment for her ‘psychological’ condition. In an act of gross negligence, Fleiss left a nasal pack in situ after the surgery and did not provide appropriate follow-up or after-care. After much suffering, another surgeon discovered the mistake, and the nasal pack was removed.

Keywords

adult olfactory epitheliumbrain developmentneurodevelopmental disorderolfactory neurogenesisschizophrenia
Type
Chapter
Information
Olfaction and the Brain , pp. 83 - 102
Publisher: Cambridge University Press
Print publication year: 2006

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