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Chapter 38 - Neuroimaging of disorders of arousal and other parasomnias

from Section 5 - Neuroimaging of sleep disorders

Published online by Cambridge University Press:  05 March 2013

By
Romy Hoque  and
Lourdes DelRosso
Edited by
Eric Nofzinger ,
Pierre Maquet  and
Michael J. Thorpy
Eric Nofzinger
Affiliation:
University of Pittsburgh
Pierre Maquet
Affiliation:
Université de Liège, Belgium
Michael J. Thorpy
Affiliation:
Sleep-Wake Disorders Center, Montefiore Medical Center, New York
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Summary

This chapter reviews the current neuroimaging literature regarding disorders of arousal and parasomnias, particularly non-rapid eye movement (NREM) parasomnias. During REM sleep the patient exhibited REM behavior disorder (RBD) with mumbling, complex hand movements, and arm/leg jerks. A repeat magnetic resonance imaging (MRI) showed persistent increased T2 weighted image (WI) hyper intense/T1 WI hypo intense lesions in the right mesencephalic/ pontine tegmentum and the right medulla. MRI of the head revealed a T2 WI hyper intense lesion at the pontomesencephalic lesion presumed to be neurosarcoidosis. Imaging modalities when used in combination with clinical electrophysiology (e.g. EEG and PSG) provide better understanding into both structure and function of electrophysiologically verified parasomnias. Future studies combining both electrophysiology and multiple neuroimaging modalities may help in both the assessment of sleep-related dissociative disorders and the development of new treatment modalities.

Keywords

MRI visual inspectionnarcolepsy patientsvoxel-based morphometrymagnetic resonance spectroscopycerebral cortexcortical surface method
Type
Chapter
Information
Neuroimaging of Sleep and Sleep Disorders , pp. 301 - 304
Publisher: Cambridge University Press
Print publication year: 2013

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