Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-08T08:18:48.540Z Has data issue: false hasContentIssue false

Chapter 19 - Imaging Comorbidities in Epilepsy: Depression

from Part IV - Mapping Consequences of the Disease

Published online by Cambridge University Press:  07 January 2019

Andrea Bernasconi
Affiliation:
Montreal Neurological Institute, McGill University
Neda Bernasconi
Affiliation:
Montreal Neurological Institute, McGill University
Matthias Koepp
Affiliation:
Institute of Neurology, University College London
Get access
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kanner, A. Psychiatric comorbidities through the life of the seizure disorder: a complex relation with a not so complex solution. Epilepsy Currents. 2014;14:323–8.Google Scholar
Fiest, KM, Dykeman, J, Patten, SB et al. Depression in epilepsy: a systematic review and meta-analysis. Neurology. 2013;80:110.CrossRefGoogle ScholarPubMed
Fuller-Thomson, E, Brennenstuhl, S. The association between depression and epilepsy in a nationally representative sample Epilepsia. 2009;50(5):1051–8.CrossRefGoogle Scholar
Kobau, R, Gilliam, F, Thurman, DJ. Prevalence of self-reported epilepsy or seizure disorder and its associations with self-reported depression and anxiety: results from the 2004 Healthstyles Survey. Epilepsia. 2006;47:1915–21.Google Scholar
Kanner, AM, Schachter, SC, Barry, JJ, et al. Depression and epilepsy, pain and psychogenic non-epileptic seizures: clinical and therapeutic perspectives. Epilepsy Behav. 2012;24:169–81.Google Scholar
Mula, M, Jauch, R, Cavanna, A, et al. Interictal dysphoric disorder and periictal dysphoric symptoms in patients with epilepsy. Epilepsia. 2010;51:1139–45.CrossRefGoogle ScholarPubMed
Kanner, AM, Soto, A, Gross-Kanner, H. Prevalence and clinical characteristics of postictal psychiatric symptoms in partial epilepsy Neurology. 2004;62:708–13.Google Scholar
Mula, M, Monaco, F. Ictal and peri-ictal psychopathology. Behav Neurol. 2011;24:21–5.Google Scholar
Forsgren, L, Nyström, L. An incident case-referent study of epileptic seizures in adults. Epilepsy Res. 1990;6:6681.Google Scholar
Hesdorffer, DC, Ishihara, L, Mynepalli, L, et al. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association. Ann Neurol. 2012;72:184–91.Google Scholar
Adelöw, C, Andersson, T, Ahlbom, A, et al. Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy. Neurology. 2012;78:396401.Google Scholar
Malykhin, NV, Coupland, NJ. Hippocampal neuroplasticity in major depressive disorder. Neuroscience. 2015;309:200–13.Google Scholar
Contoreggi, C. Corticotropin releasing hormone and imaging, rethinking the stress axis. Nucl Med Biol. 2015;42:323–39.Google Scholar
Drevets, WC. Prefrontal cortical-amygdalar metabolism in major depression. Ann N Y Acad Sci. 1999;877:614–37.Google Scholar
Quiske, A, Helmstaedter, C, Lux, S, et al. Depression in patients with temporal lobe epilepsy is related to mesial temporal sclerosis. Epilepsy Res. 2000;39:121–5.Google Scholar
Nees, H, Moriarty, J, Kitchen, ND, et al. Psychosocial and neurobehavioral factors related to surgical treatment for partial epilepsy: a multivariate analysis. Epilepsy Behav. 2001;2:135–9.Google Scholar
Baxendale, SA, Thompson, PJ, Duncan, JS. Epilepsy & depression: the effects of comorbidity on hippocampal volume—a pilot study. Seizure. 2005;14:435–8.Google Scholar
Devinsky, O, Barr, WB, Vickrey, BG, et al. Changes in depression and anxiety after resective surgery for epilepsy. Neurology. 2005;65:1744–9.CrossRefGoogle ScholarPubMed
Briellmann, RS, Hopwood, MJ, Jackson, GD. Major depression in temporal lobe epilepsy with hippocampal sclerosis: clinical and imaging correlates. J Neurol Neurosurg Psychiatry. 2007;78:1226–30.Google Scholar
Adams, SJ, O’Brien, TJ, Lloyd, J, et al. Neuropsychiatric morbidity in focal epilepsy. Br J Psychiatry. 2008;192:464–9.Google Scholar
Shamim, S, Hasler, G, Liew, C, et al. Temporal lobe epilepsy, depression, and hippocampal volume. Epilepsia. 2009;50:1067–71.CrossRefGoogle ScholarPubMed
Hecimovic, H, Santos, J, Price, JL, et al. Severe hippocampal atrophy is not associated with depression in temporal lobe epilepsy. Epilepsy Behav. 2014;34:914.Google Scholar
Richardson, EJ, Griffith, HR, Martin, RC, et al. Structural and functional neuroimaging correlates of depression in temporal lobe epilepsy. Epilepsy Behav. 2007;10:242–9.Google Scholar
van Elst, LT, Groffmann, M, Ebert, D, Schulze-Bonhage A. Amygdala volume loss in patients with dysphoric disorder of epilepsy. Epilepsy Behav. 2009;16:105–12.Google Scholar
Salgado, PC, Yasuda, CL, Cendes, F. Neuroimaging changes in mesial temporal lobe epilepsy are magnified in the presence of depression. Epilepsy Behav. 2010;19:422–7.Google Scholar
Butler, T, Blackmon, K, McDonald, CR, et al. Cortical thickness abnormalities associated with depressive symptoms in temporal lobe epilepsy. Epilepsy Behav. 2012;23:64–7.Google Scholar
Doucet, GE, Skidmore, C, Sharan, AD, et al. Functional connectivity abnormalities vary by amygdala subdivision and are associated with psychiatric symptoms in unilateral temporal epilepsy. Brain Cogn. 2013;83:171–82.Google Scholar
Kemmotsu, N, Kucukboyaci, NE, Leyden, KM, et al. Frontolimbic brain networks predict depressive symptoms in temporal lobe epilepsy. Epilepsy Res. 2014;108:1554–63.Google Scholar
Stretton, J, Pope, RA, Winston, GP, et al. Temporal lobe epilepsy and affective disorders: the role of the subgenual anterior cingulate cortex. J Neurol Neurosurg Psychiatry. 2015;86:144–51.Google Scholar
Bilevicius, E, Yasuda, CL, Silva, MS, et al. Antiepileptic drug response in temporal lobe epilepsy: a clinical and MRI morphometry study. Neurology. 2010;75:1695–701.Google Scholar
Jacka, FN, Cherbuin, N, Anstey, KJ, et al. Western diet is associated with a smaller hippocampus: a longitudinal investigation. BMC Med. 2015;13(1):215.Google Scholar
Kerestes, R, Davey, CG, Stephanou, K, et al. Functional brain imaging studies of youth depression: A systematic review. NeuroImage Clin. 2014;4:209–31.Google Scholar
Miller, CH, Hamilton, JP, Sacchet, MD, et al. Meta-analysis of functional neuroimaging of major depressive disorder in youth. JAMA Psychiatry. 2015;72:1045–53.Google Scholar
Kaiser, RH, Andrews-Hanna, JR, Wager, TD, et al. Large-scale network dysfunction in major depressive disorder: a meta-analysis of resting-state functional connectivity JAMA Psychiatry. 2015;72(6):603–11.Google Scholar
Pope, RA, Centeno, M, Flügel, D, et al. Neural correlates of de novo depression following left temporal lobe epilepsy surgery: a voxel based morphometry study of pre-surgical structural MRI. Epilepsy Res. 2014;108:517–25.Google Scholar
Wrench, JM, Wilson, SJ, Bladin, PF, et al. Hippocampal volume and depression: insights from epilepsy surgery. J Neurol Neurosurg Psychiatry. 2009;80:539–44.CrossRefGoogle ScholarPubMed
Paparrigopoulos, T, Ferentinos, P, Brierley, B, et al. Relationship between post-operative depression/anxiety and hippocampal/amygdala volumes in temporal lobectomy for epilepsy. Epilepsy Res. 2008;81:30–5.Google Scholar
Gilliam, FG, Maton, BM, Martin, RC, et al. Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy. Neurology. 2007;68:364–8.Google Scholar
Bromfield, EB, Altshuler, L, Leiderman, DB, et al. Cerebral metabolism and depression in patients with complex partial seizures. Arch Neurol. 1992;49:617–25.Google Scholar
Salzberg, M, Taher, T, Davie, M, et al. Depression in temporal lobe epilepsy surgery patients: an FDG-PET study. Epilepsia. 2006;47:2125–30.Google Scholar
McGinnity, CJ, Koepp, MJ, Hammers, A et al. NMDA receptor binding in focal epilepsies. J Neurol Neurosurg Psychiatry. 2015;86:1150–7.Google Scholar
Bagdy, G, Kecskemeti, V, Rib, P, et al. Serotonin and epilepsy. J Neurochem. 2007;100:857–73.Google Scholar
Drevets, WC, Thase, ME, Moses-Kolko, EL, et al. Serotonin-1A receptor imaging in recurrent depression: replication and literature review. Nucl Med Biol. 2007;34:865–77.Google Scholar
Bhagwagar, Z, Rabiner, EA, Sargent, PA, et al. Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Mol Psychiatry. 2004;9:386–92.Google Scholar
Shively, CA, Friedman, DP, Gage, HD, et al. Behavioral depression and positron emission tomography-determined serotonin 1 A receptor binding potential in cynomolgus monkeys. Arch Gen Psychiatry. 2006;63:396403.Google Scholar
Parsey, RV, Oquendo, MA, Ogden, RT, et al. Altered serotonin 1 A binding in major depression: a [carbonyl-C-11]WAY100635 positron emission tomography study. Biol Psychiatry. 2006;59:106–13.Google Scholar
Moses-Kolko, EL, Price, JC, Thase, ME, et al. Measurement of 5-HT1A receptor binding in depressed adults before and after antidepressant drug treatment using positron emission tomography and [11C]WAY-100635. Synapse. 2007;61:523–30.Google Scholar
Toczek, MT, Carson, RE, Lang, L, et al. PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy. Neurology. 2003;60:749–56.Google Scholar
Savic, I, Lindstrom, P, Gulyas, B, et al. Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology. 2004;62:1343–51.Google Scholar
Merlet, I, Ostrowsky, K, Costes, N, et al. 5-HT1A receptor binding and intracerebral activity in temporal lobe epilepsy: an [18F]MPPF-PET study. Brain. 2004;127:900–13.Google Scholar
Giovacchini, G, Toczek, MT, Bonwetsch, R, et al. 5-HT 1 A receptors are reduced in temporal lobe epilepsy after partial-volume correction. J Nucl Med. 2005;46:1128–35.Google Scholar
Theodore, WH, Martinez, AR, Khan, OI, et al. PET imaging of serotonin 1 A receptors and cerebral glucose metabolism for temporal lobectomy. J Nucl Med. 2012;53:1375–82.CrossRefGoogle ScholarPubMed
Theodore, WH, Hasler, G, Giovacchini, G, et al. Reduced hippocampal 5HT1A PET receptor binding and depression in temporal lobe epilepsy. Epilepsia. 2007;48:1526–30.Google Scholar
Theodore, WH, Wiggs, EA, Martinez, AR, et al. Serotonin 1 A receptors, depression, and memory in temporal lobe epilepsy. Epilepsia. 2012;53:129–33.Google Scholar
Lothe, A, Didelot, A, Hammers, A, et al. Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study. Brain. 2008;131:2765–82.Google Scholar
Sargent, PA, Kjaer, KH, Bench, CJ, et al. Brain serotonin 1 A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment. Arch Gen Psychiatry. 2000;57:174–80.Google Scholar
Theodore, WH, Giovacchini, G, Bonwetsch, R, et al. The effect of antiepileptic drugs on 5-HT1A receptor binding measured by positron emission tomography. Epilepsia. 2006;47:499503.Google Scholar
Hasler, G, Bonwetsch, R, Giovacchini, G, et al. 5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression. Biol Psychiatry. 2007;62:1258–64.Google Scholar
Caspi, A, Sugden, K, Moffitt, TE, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science. 2003;301:386–9.Google Scholar
Stefulj, J, Bordukalo-Niksic, T, Hecimovic, H, et al. Epilepsy and serotonin (5-HT): variation of 5-HT related genes in temporal lobe epilepsy. Neurosci Lett. 2010;478:2931.Google Scholar
Meyer, JH, Houle, S, Sagrati, S, et al. Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes. Arch Gen Psychiatry. 2004;61:1271–9.Google Scholar
Cannon, DM, Ichise, M, Rollis, D, et al. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and C-11 DASB: comparison with bipolar disorder. Biol Psychiatry. 2007;62:870–7.Google Scholar
Parsey, RV, Hastings, RS, Oquendo, MA, et al. Lower serotonin transporter binding potential in the human brain during major depressive episodes. Am J Psychiatry. 2006;163:52–8.Google Scholar
Oquendo, MA, Hastings, RS, Huang, YY, et al. Brain serotonin transporter binding in depressed patients with bipolar disorder using positron emission tomography. Arch Gen Psychiatry. 2007;64:201–8.Google Scholar
Spies, M, Knudsen, GM, Lanzenberger, R, et al. The serotonin transporter in psychiatric disorders: insights from PET imaging. Lancet Psychiatry. 2015;2:743–55.CrossRefGoogle ScholarPubMed
Martinez, A, Finegersh, A, Cannon, DM et al. The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy. Neurology. 2013;80:1465–71.Google Scholar
Alper, K, Schwartz, KA, Kolts, RL, et al. Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports. Biol Psychiatry. 2007;62:345–54.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×