Book contents
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- 5A DHEA Is an Effective Treatment for Poor Responders
- 5B DHEA Is an Effective Treatment for Poor Responders
- 6A The Addition of LH/hCG to FSH Improves IVF Outcome
- 6B The Addition of LH/hCG to FSH Improves IVF Outcome
- 7A Acupuncture Is a Useful Adjuvant for Fertility Treatment
- 7B Acupuncture Is a Useful Adjuvant for Fertility Treatment
- 8A There Is a Role for Pre-conceptional Treatment with CoQ10
- 8B There Is a Role for Pre-conceptional Treatment with CoQ10
- 9A There Is a Role for Pre-conceptional Treatment with Vitamin D
- 9B There Is a Role for Pre-conception Treatment with Vitamin D
- 10A Natural Killer Cell Assay in the Blood Is a Useless Investigation
- 10B Natural Killer Cell Assay in the Blood Is a Useless Investigation
- 11A Intralipid Therapy Has a Place in Infertility Treatment
- 11B Intralipid Therapy Has a Place in Infertility Treatment
- 12A The Endometrial Scratch Has Had Its Day
- 12B The Endometrial Scratch Has Had Its Day
- 13A Corticosteroid Therapy Is Useful in Assisting Implantation
- 13B Corticosteroid Therapy Is Useful in Assisting Implantation
- Section III The Best Policy
- Section IV Embryology
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- Index
- References
8A - There Is a Role for Pre-conceptional Treatment with CoQ10
For
from Section II - IVF Add-ons
Published online by Cambridge University Press: 25 November 2021
- 50 Big Debates in Reproductive Medicine
- Series page
- 50 Big Debates in Reproductive Medicine
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section I Limits for IVF
- Section II IVF Add-ons
- 5A DHEA Is an Effective Treatment for Poor Responders
- 5B DHEA Is an Effective Treatment for Poor Responders
- 6A The Addition of LH/hCG to FSH Improves IVF Outcome
- 6B The Addition of LH/hCG to FSH Improves IVF Outcome
- 7A Acupuncture Is a Useful Adjuvant for Fertility Treatment
- 7B Acupuncture Is a Useful Adjuvant for Fertility Treatment
- 8A There Is a Role for Pre-conceptional Treatment with CoQ10
- 8B There Is a Role for Pre-conceptional Treatment with CoQ10
- 9A There Is a Role for Pre-conceptional Treatment with Vitamin D
- 9B There Is a Role for Pre-conception Treatment with Vitamin D
- 10A Natural Killer Cell Assay in the Blood Is a Useless Investigation
- 10B Natural Killer Cell Assay in the Blood Is a Useless Investigation
- 11A Intralipid Therapy Has a Place in Infertility Treatment
- 11B Intralipid Therapy Has a Place in Infertility Treatment
- 12A The Endometrial Scratch Has Had Its Day
- 12B The Endometrial Scratch Has Had Its Day
- 13A Corticosteroid Therapy Is Useful in Assisting Implantation
- 13B Corticosteroid Therapy Is Useful in Assisting Implantation
- Section III The Best Policy
- Section IV Embryology
- Section V Ethics and Statistics
- Section VI Male-factor Infertility
- Section VII Genetics
- Section VIII Ovarian Stimulation
- Section IX Hormones and the Environment
- Index
- References
Summary
Making evidence-based decisions with a common primary outcome measure is a key tenet of ethical and effective clinical practice in ART in a rapidly evolving scientific landscape. However, interpretation of the evidence must be underpinned by sound biological reasoning, and this is especially true when it comes to adjunct antioxidant supplementation in IVF. Furthermore, study design for assessing natural compounds is typically based on protocols established to assess drug-based therapies that often fail to effectively evaluate efficacy of individual nutrients that occur naturally in vivo and often groups study patients together with many differing aetiologies. Finally, the gold standard in terms of IVF outcome measure is live birth rate (LBR), but it is vital that we move beyond this narrow perspective and consider obstetric and child health outcomes. With this in mind I will describe the role for pre-conceptional treatment with CoQ10.
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- Information
- 50 Big Debates in Reproductive Medicine , pp. 40 - 43Publisher: Cambridge University PressPrint publication year: 2021