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Debate 45A - Should Adjuvant Hysterectomy be Performed for Patients with Locally Advanced Cervical Cancer Treated with Concurrent Chemoradiotherapy?

Yes

from Section V - Cervical Cancer

Published online by Cambridge University Press:  20 July 2023

By
Dib Sassine ,
Alexandra Diggs  and
Yukio Sonoda
Edited by
Dennis S. Chi ,
Nisha Lakhi  and
Nicoletta Colombo
Dennis S. Chi
Affiliation:
Memorial Sloan-Kettering Cancer Center, New York
Nisha Lakhi
Affiliation:
Richmond University Medical Center, Staten Island
Nicoletta Colombo
Affiliation:
University of Milan-Bicocca
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Summary

Adjuvant hysterectomy (AH) following concurrent chemoradiation (CCRT) for the management of locally advanced cervical cancer (LACC) is still subject for debate. While it is still not standard of care to perform adjuvant hysterectomy after CCRT due to limited data supporting this approach, as well as possible increased morbidity, there are practitioners who choose this approach in the hope of decreasing local recurrence, especially in the setting of chemo and radiation-resistant tumors after excluding metastatic disease. In this review we will focus on the available data that supports AH in the management of LACC.

Type
Chapter
Information
50 Big Debates in Gynecologic Oncology , pp. 272 - 274
Publisher: Cambridge University Press
Print publication year: 2023

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References

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Morice, P, et al. Results of the GYNECO 02 study, an FNCLCC phase III trial comparing hysterectomy with no hysterectomy in patients with a (clinical and radiological) complete response after chemoradiation therapy for stage IB2 or II cervical cancer. Oncologist 2012;17(1):64–71.Google Scholar
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Yang, J, et al. Extrafascial hysterectomy after concurrent chemoradiotherapy in locally advanced cervical adenocarcinoma. J Gynecol Oncol 2016;27(4):e40.CrossRefGoogle ScholarPubMed

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