Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-28T19:12:05.111Z Has data issue: false hasContentIssue false

Debate 51A - Is Pelvic Exenteration an Option for a Pelvic Recurrence of a Vulvar/Vaginal Melanoma after Previous Radiation Therapy?

Yes

from Section VI - Vaginal and Vulvar Cancer

Published online by Cambridge University Press:  20 July 2023

By
John P. Geisler  and
Kelly J. Manahan
Edited by
Dennis S. Chi ,
Nisha Lakhi  and
Nicoletta Colombo
Dennis S. Chi
Affiliation:
Memorial Sloan-Kettering Cancer Center, New York
Nisha Lakhi
Affiliation:
Richmond University Medical Center, Staten Island
Nicoletta Colombo
Affiliation:
University of Milan-Bicocca
Get access

Summary

Vulvar/vaginal melanomas are uncommon malignancies. Due to the relative infrequency of vulvo-vaginal melanomas, many treatments are used after initial surgical resection. Pelvic radiation may be used in patients who are initially unresectable, have positive lymph nodes or have close margins. Pelvic exenteration after pelvic recurrence of vulvo-vaginal melanomas in a radiated field may be necessary and appropriate in select patients.

Type
Chapter
Information
50 Big Debates in Gynecologic Oncology , pp. 307 - 309
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Boer, FL, et al. Vulvar malignant melanoma: pathogenesis, clinical behaviour and management: review of the literature. Cancer Treat Rev 2019;73:91–103.CrossRefGoogle ScholarPubMed
Saito, T, et al. Japan Society of Gynecologic Oncology guidelines 2015 for the treatment of vulvar cancer and vaginal cancer. Int J Clin Oncol 2018;23:201–234.CrossRefGoogle Scholar
Mert, I, et al. Vulvar/vaginal melanoma: an updated surveillance epidemiology and end results database review, comparison with cutaneous melanoma and significance of racial disparities. Int J Gynecol Cancer 2013;23:1118–1125.CrossRefGoogle ScholarPubMed
Geisler, JP, et al. Pelvic exenteration for malignant melanomas of the vagina or urethra with over 3 mm of invasion. Gynecol Oncol 1995;59:338–341.CrossRefGoogle ScholarPubMed
Frumovitz, M, et al. Primary malignant melanoma of the vagina. Obstet Gynecol 2010;116:1358–1365.CrossRefGoogle ScholarPubMed
Look, KY, et al. Vulvar melanoma reconsidered. Cancer 1993;72:143–146.3.0.CO;2-M>CrossRefGoogle ScholarPubMed
Agrawal, S, et al. The benefits of adjuvant radiation therapy after therapeutic lymphadenectomy for clinically advanced, high-risk, lymph node-metastatic melanoma. Cancer 2009;115:5836–5844.CrossRefGoogle ScholarPubMed
Xing, Y, et al. Contemporary diagnostic imaging modalities for the staging and surveillance of melanoma patients: a meta-analysis. J Natl Cancer Inst 2011;103:129–142.Google Scholar
Rezk, YA, et al. A prospective study of quality of life in patients undergoing pelvic exenteration: interim results. Gynecol Oncol 2013;128:191–197.CrossRefGoogle ScholarPubMed
Schneider, A, et al. Current developments for pelvic exenteration in gynecologic oncology. Curr Opin Obstet Gynecol 2009;21:4–9.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×