Research was conducted for 2 yr at Marianna, AR, to determine whether the fall-planted cover crops rye, wheat, turnip, and a blend of brown and white mustard (Caliente) would aid weed management programs in conservation-tilled, enhanced, glyphosate-resistant cotton. Wheat and rye easily were established both years and turnip and mustard blend stands were better in the second year. The cover crops alone were more suppressive of Palmer amaranth, pitted morningglory, and goosegrass in 2007 than in 2008. Rye was generally superior to wheat in suppressing the three evaluated weeds. Once herbicides were applied, there were seldom differences among cover crops for a particular herbicide program as a result of the highly efficacious herbicide programs. Cotton yields were not affected by wheat, rye, or the mustard blend, but yields were lowest in plots that followed turnip both years, possibly because of allelopathy. Integration of cover crops, especially cereals, into conservation-tilled, glyphosate-resistant cotton aided early-season weed management and could reduce the selection of glyphosate for herbicide resistance.