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Postpartum hemorrhage (PPH) is the most common cause of maternal mortality worldwide and uterine atony is the most common cause of PPH. Timely diagnosis and prompt intervention are crucial to manage this potentially life-threatening condition. Early blood product replacement and interventions aimed at reducing bleeding and restoring uterine contractility are key components of treatment. A progression of medical therapy, uterine compression, and surgical intervention may be needed to resolve the PPH. A standardized approach to management of PPH due to atony can help improve outcomes. The Alliance for Innovation on Maternal Health provides information regarding care bundles addressing a multidisciplinary approach to treating PPH and may be a resource for labor and delivery units in their efforts to improve care.
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