This article integrates field, powder X-ray diffraction and microstructural data to constrain deformation mechanisms in and the rheology of granite-derived fault rocks exposed along the SE side of the crustal-scale, strike-slip Kellyland fault zone. Deformation in this area of the Kellyland fault zone localized during cooling and is marked by (1) foliated granite, (2) a ∼50 m wide band of pulverized foliated granite, (3) a ∼2.8 m wide breccia zone hosting coeval shear zones, and (4) a >100 m wide ultramylonite zone. The earliest fabric in the foliated granite is defined by elongated quartz grains, and quartz dislocation creep was the rate-controlling deformation mechanism. Seismogenic deformation initiated when recorded flow stresses reached 96–104 MPa at temperatures of 400–450 °C and is marked by coeval pulverization and formation of breccia. Interseismic viscous creep at similar flow stresses is recorded by mutual cross-cutting relationships between breccia-hosted shear zones, brittle fractures and pseudotachylyte. Field and microstructural observations indicate that breccia-hosted shear zones are low-strain equivalents of the >100 m wide ultramylonite zone, and seismogenic deformation abated as the ultramylonite formed. The rheology of ultramylonites was governed by grain-size-sensitive creep at 112–124 MPa flow stresses. Hence, from the onset of seismogenesis, the Kellyland fault zone was likely a constant-stress system wherein the rate-controlling mechanism shifted from episodic seismogenic slip and interseismic viscous creep to steady state grain-size-sensitive creep in ultramylonites derived from brittle fault rocks. Flow stresses recorded by these rocks also imply that the whole zone was relatively weak if the brittle–viscous transition and uppermost viscous zone are the strongest part of the crust.