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2 results

  • Chapter 11 - Ischemic Stroke and Transient Ischemic Attack

  • from Section 3 - Specific Neurological Disorders in Emergency Medicine
  • Edited by Thomas P. Campbell, Allegheny Health Network, Pittsburgh, Kevin M. Kelly, Allegheny Health Network, Pittsburgh
  • Book:
    Handbook of Emergency Neurology
    Published online:
    10 January 2024
    Print publication:
    17 August 2023, pp 137-172

  • Summary

    In the United States, one stroke occurs every 40 seconds on average. Ischemic stroke is a leading cause of serious long-term disability and the fifth leading cause of death. Every year, 795,000 people experience a new or recurrent stroke. In 2018, stroke accounted for 1 of every 19 deaths. Stroke typically occurs suddenly, with symptoms of motor weakness, impaired speech, vision loss, or numbness, and can lead to significant disability. The financial burden of stroke, including direct medical costs and potential wages lost, is greater than $30 billion per year. Time-based acute stroke treatments improve functional outcome and reduce mortality, which makes rapid recognition of stroke of utmost importance.

  • Acute allergic reaction due to the administration of fibrinolytic therapy for ST-segment elevation myocardial infarction: case report and discussion

  • Geoff C. Mills, Robert T. Arntfield, Robert J. Sedran
  • Journal:
    Canadian Journal of Emergency Medicine / Volume 5 / Issue 6 / November 2003
    Published online by Cambridge University Press:
    21 May 2015, pp. 421-423
    Print publication:
    November 2003
    • Article
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  • Although a rare phenomenon, acute allergic reactions to fibrinolytic and heparin therapy have been described in the literature. We report the case of a 63-year-old woman who experienced a severe anaphylactic reaction while undergoing fibrinolytic therapy with tissue plasminogen activator for an ST-segment elevation myocardial infarction. Overall outcome was successful, but patient morbidity was increased because of the reaction and the subsequent therapy administered.