Investigations have been made to evaluate the development of Spodoptera littoralis as affected by feeding on a standard artificial diet containing powder of some plant species known to be resistant to the infestation of this insect. Trials were also made to find out whether the effect of these plants facilitate the potency of Bacillus thuringiensis var entomocidus HD-635 vs. the target insect. The results revealed that powders of pomegranate peel, guava leaves and lemon grass, greatly affected the insect development in terms of larval duration, larval and pupal weights, deformities in pupae and moths, percentage of emergence, egg production and hatching. This may be correlated to the chemical constituents of these plants. A marked increase was observed in the potency of B. thuringiensis endotoxin preparation vs. S. littoralis when combined with some of the tested powdered plants or its extracts but in varying degrees.