It is well known that the classical local projection method as well as residual-based stabilization techniques, as for instancestreamline upwind Petrov-Galerkin (SUPG), are optimal on isotropicmeshes. Here we extend the local projection stabilization for the Navier-Stokes system to anisotropic quadrilateral meshes in two spatial dimensions. Wedescribe the new methodand prove an a priori error estimate. This method leads on anisotropic meshes to qualitatively better convergence behavior than other isotropicstabilization methods.The capability of the methodis illustrated by means of two numerical test problems.