A description of the Herschel Space Observatory and the Atacama Large Millimeter Array is presented. Their scientific potential and possible synergistic effects with ELTs is discussed. Herschel is a space-based far-infrared and submillimeter telescope to be launched in 2008 and will offer 3 years of routine science operations. ALMA will become fully operational around 2012 and will co-exist with ELTs. The synergy of being able to observe the same objects with similar angular resolution and sensitivity at long and short wavelengths will contribute to our understanding of astrophysical objects and processes in general.